"Integrin alpha4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin alpha subunit that is unique in that it does not contain an I-domain, and its proteolytic cleavage site is near the middle of the extracellular portion of the polypeptide rather than close to the membrane, as in other integrin alpha subunits.
| Descriptor ID |
D039441
|
| MeSH Number(s) |
D12.776.543.750.705.408.100.450
|
| Concept/Terms |
Integrin alpha4- Integrin alpha4
- CD49d Antigens
- Antigens, CD49d
- CD49d Antigen
- alpha4 Integrin
- Integrin, alpha4
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha4".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha4".
This graph shows the total number of publications written about "Integrin alpha4" by people in this website by year, and whether "Integrin alpha4" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Integrin alpha4" by people in Profiles.
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Zhang X, Weissman SM, Newburger PE. Long intergenic non-coding RNA HOTAIRM1 regulates cell cycle progression during myeloid maturation in NB4 human promyelocytic leukemia cells. RNA Biol. 2014; 11(6):777-87.
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Juillerat P, Wasan SK, Fowler SA, Friedman S, Pabby VK, Coukas JA, Barto AE, Pellish R, Germansky KA, Cheifetz AS, Korzenik JR, Farraye FA, Yajnik V. Efficacy and safety of natalizumab in Crohn's disease patients treated at 6 Boston academic hospitals. Inflamm Bowel Dis. 2013 Oct; 19(11):2457-63.
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Gan Y, Liu R, Wu W, Bomprezzi R, Shi FD. Antibody to a4 integrin suppresses natural killer cells infiltration in central nervous system in experimental autoimmune encephalomyelitis. J Neuroimmunol. 2012 Jun 15; 247(1-2):9-15.
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Ansari AA, Reimann KA, Mayne AE, Takahashi Y, Stephenson ST, Wang R, Wang X, Li J, Price AA, Little DM, Zaidi M, Lyles R, Villinger F. Blocking of a4?7 gut-homing integrin during acute infection leads to decreased plasma and gastrointestinal tissue viral loads in simian immunodeficiency virus-infected rhesus macaques. J Immunol. 2011 Jan 15; 186(2):1044-59.
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Messmer-Blust AF, Balasubramanian S, Gorbacheva VY, Jeyaratnam JA, Vestal DJ. The interferon-gamma-induced murine guanylate-binding protein-2 inhibits rac activation during cell spreading on fibronectin and after platelet-derived growth factor treatment: role for phosphatidylinositol 3-kinase. Mol Biol Cell. 2010 Jul 15; 21(14):2514-28.