"Yolk Sac" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The first of four extra-embryonic membranes to form during EMBRYOGENESIS. In REPTILES and BIRDS, it arises from endoderm and mesoderm to incorporate the EGG YOLK into the DIGESTIVE TRACT for nourishing the embryo. In placental MAMMALS, its nutritional function is vestigial; however, it is the source of INTESTINAL MUCOSA; BLOOD CELLS; and GERM CELLS. It is sometimes called the vitelline sac, which should not be confused with the VITELLINE MEMBRANE of the egg.
Descriptor ID |
D015017
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MeSH Number(s) |
A10.615.284.981 A16.254.750.981 A16.331.800
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Concept/Terms |
Yolk Sac- Yolk Sac
- Sac, Yolk
- Sacs, Yolk
- Yolk Sacs
- Vitelline Sac of Embryo
- Embryo Vitelline Sac
- Embryo Vitelline Sacs
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Below are MeSH descriptors whose meaning is more general than "Yolk Sac".
Below are MeSH descriptors whose meaning is more specific than "Yolk Sac".
This graph shows the total number of publications written about "Yolk Sac" by people in this website by year, and whether "Yolk Sac" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 |
2007 | 0 | 1 | 1 |
2013 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Yolk Sac" by people in Profiles.
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Nandadasa S, Kraft CM, Wang LW, O'Donnell A, Patel R, Gee HY, Grobe K, Cox TC, Hildebrandt F, Apte SS. Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis. Nat Commun. 2019 02 27; 10(1):953.
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Blackburn DG, Anderson KE, Lo AR, Marquez EC, Callard IP. Placentation in watersnakes II: Placental ultrastructure in Nerodia erythrogaster (Colubridae: Natricinae). J Morphol. 2017 05; 278(5):675-688.
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Rhee S, Guerrero-Zayas MI, Wallingford MC, Ortiz-Pineda P, Mager J, Tremblay KD. Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development. PLoS One. 2013; 8(3):e58828.
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Rivera RM, Stein P, Weaver JR, Mager J, Schultz RM, Bartolomei MS. Manipulations of mouse embryos prior to implantation result in aberrant expression of imprinted genes on day 9.5 of development. Hum Mol Genet. 2008 Jan 01; 17(1):1-14.
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Yang X, Castilla LH, Xu X, Li C, Gotay J, Weinstein M, Liu PP, Deng CX. Angiogenesis defects and mesenchymal apoptosis in mice lacking SMAD5. Development. 1999 Apr; 126(8):1571-80.