Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.

Descriptor ID	D007141
MeSH Number(s)	D12.644.541.500.697 D12.776.124.486.485.538.500 D12.776.124.486.485.680.697 D12.776.124.790.651.538.500 D12.776.124.790.651.680.660 D12.776.377.715.548.538.500 D12.776.377.715.548.680.660
Concept/Terms	Immunoglobulin Fc Fragments Immunoglobulin Fc Fragments Fc Fragments, Immunoglobulin Immunoglobulins, Fc Fragment Fc Fragment Immunoglobulins Fragment Immunoglobulins, Fc Immunoglobulin Fc Fragment Fc Fragment, Immunoglobulin Immunoglobulins, Fc Fc Fragments Fc Immunoglobulins

Below are MeSH descriptors whose meaning is more general than "Immunoglobulin Fc Fragments".

Below are MeSH descriptors whose meaning is related to "Immunoglobulin Fc Fragments".

Below are MeSH descriptors whose meaning is more specific than "Immunoglobulin Fc Fragments".