Anemia, Sickle Cell

"Anemia, Sickle Cell" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S.

Descriptor ID	D000755
MeSH Number(s)	C15.378.071.141.150.150 C15.378.420.155 C16.320.070.150 C16.320.365.155
Concept/Terms	Anemia, Sickle Cell Anemia, Sickle Cell Anemias, Sickle Cell Sickle Cell Anemias Hemoglobin S Disease Disease, Hemoglobin S Hemoglobin S Diseases Sickle Cell Anemia Sickle Cell Disorders Cell Disorder, Sickle Cell Disorders, Sickle Sickle Cell Disorder Sickling Disorder Due to Hemoglobin S HbS Disease Sickle Cell Disease Cell Disease, Sickle Cell Diseases, Sickle Sickle Cell Diseases

Below are MeSH descriptors whose meaning is more general than "Anemia, Sickle Cell".

Diseases [C]
Hemic and Lymphatic Diseases [C15]
Hematologic Diseases [C15.378]
Anemia [C15.378.071]
Anemia, Hemolytic [C15.378.071.141]
Anemia, Hemolytic, Congenital [C15.378.071.141.150]
Anemia, Sickle Cell [C15.378.071.141.150.150]
Hemoglobinopathies [C15.378.420]
Anemia, Sickle Cell [C15.378.420.155]
Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
Genetic Diseases, Inborn [C16.320]
Anemia, Hemolytic, Congenital [C16.320.070]
Anemia, Sickle Cell [C16.320.070.150]
Hemoglobinopathies [C16.320.365]
Anemia, Sickle Cell [C16.320.365.155]

Below are MeSH descriptors whose meaning is related to "Anemia, Sickle Cell".

Below are MeSH descriptors whose meaning is more specific than "Anemia, Sickle Cell".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Anemia, Sickle Cell" by people in this website by year, and whether "Anemia, Sickle Cell" was a major or minor topic of these publications.

Bar chart showing 59 publications over 22 distinct years, with a maximum of 5 publications in 2022 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1997	2	0	2
2004	0	1	1
2005	1	2	3
2006	2	0	2
2008	3	0	3
2009	2	0	2
2010	1	1	2
2011	1	1	2
2012	3	0	3
2014	3	0	3
2016	1	0	1
2017	2	0	2
2018	3	0	3
2019	1	2	3
2020	3	0	3
2021	3	1	4
2022	5	0	5
2023	2	0	2
2024	4	1	5
2025	3	1	4
2026	2	1	3

Below are the most recent publications written about "Anemia, Sickle Cell" by people in Profiles.

Zeng AGX, Nagree MS, Jakobsen NA, Shah S, Varesi A, Kang JRW, Murison A, Cheong JG, Turkalj S, Zhang X, Radtke FA, Abera TA, Lim INX, Jin L, Ara?jo J, Aguilar-Navarro AG, Parris D, McLeod J, Kim H, Lee HS, Zhang L, Boulanger M, Bader E, Gbeha E, Parkhurst CN, Wagenblast E, Flores-Figueroa E, Wang B, Schwartz GW, Shultz LD, Nam AS, Grimes HL, Josefowicz SZ, Awadalla P, Vyas P, Dick JE, Xie SZ. Human haematopoietic stem cells remember inflammatory stress. Nature. 2026 Jul; 655(8122):458-467.

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Blakey AO, Maurillo AF, Amaro CM, Kavanagh PL, Garg A, Drainoni ML, Long K. Moving on Up: Shifting Sickle Cell Disease Management During Adolescence in Preparation for Adulthood. Pediatr Blood Cancer. 2026 Aug; 73(8):e70317.

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Montano-Campos JF, Adair JE, Basu A, Kyeyune RB, Bayigga L, Kityo-Mutuluuza C, Hansen R. Cost-effectiveness of gene therapy for sickle cell disease in Uganda: tailoring high-income evidence to Uganda's context. Gene Ther. 2026 Mar; 33(2):109-117.

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Burrowes SA, Jones KC, Williams CJ, Neri CM, Klings ES, Bellamy SL, Walkey AJ, Drainoni ML, Cohen RT. Supportive noninvasive ventilation for acute chest syndrome prevention in hospitalized children with sickle cell disease: Determinants of implementation. J Hosp Med. 2026 Feb; 21(2):152-163.

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DeBaun MR, Staples-Horne M, Sadacharan R, Braverman P, Shah N, Strouse J, Orsini D, Lee CD, Barnert ES. Implementing ASH's guidelines for acute medical care for incarcerated children and adults with sickle cell disease. Blood Adv. 2025 Jun 10; 9(11):2744-2750.

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Zhang Z, Yildirim M, Keskinocak P, Dasthagirisaheb YBS, Hinderstein S, Tran K, Crockett M, Burns M, Johnson H, Popstefanija M, Madoff LC, Pelton SI, Yildirim I. Serotype specific pneumococcal vaccine effectiveness in children with sickle cell disease: A two-decade analysis. Vaccine. 2025 May 22; 56:127193.

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Lee JM, Zeng J, Liu P, Nguyen MA, Suchenski Loustaunau D, Bauer DE, Kurt Yilmaz N, Wolfe SA, Schiffer CA. Direct delivery of Cas-embedded cytosine base editors as ribonucleoprotein complexes for efficient and accurate editing of clinically relevant targets. Nucleic Acids Res. 2025 01 07; 53(1).

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Zeng J, Nguyen MA, Liu P, da Silva LF, Levesque S, Lin LY, Justus DG, Petri K, Clement K, Porter SN, Verma A, Neri NR, Rosanwo T, Ciuculescu MF, Abriss D, Mintzer E, Maitland SA, Demirci S, Cha HJ, Orkin SH, Tisdale JF, Williams DA, Zhu LJ, Pruett-Miller SM, Pinello L, Joung JK, Pattanayak V, Manis JP, Armant M, Pellin D, Brendel C, Wolfe SA, Bauer DE. Gene editing without ex?vivo culture evades genotoxicity in human hematopoietic stem cells. Cell Stem Cell. 2025 Feb 06; 32(2):191-208.e11.

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Blakey AO, Amaro CM, Eilenberg JS, Brochier A, Kavanagh PL, Garg A, Drainoni ML, Long K. Characterizing medical decision-making in sickle cell disease during childhood: Qualitative perspectives of caregivers. Pediatr Blood Cancer. 2024 Dec; 71(12):e31307.

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Cohen RT, Burrowes SAB, Williams CJ, Neri CM, Klings ES, Jones KC, Walkey AJ, Drainoni ML. SNAP: Supportive non-invasive ventilation for acute chest syndrome prevention for hospitalized children with sickle cell disease: Perspectives of patients, parents, and the healthcare team. Pediatr Blood Cancer. 2024 Sep; 71(9):e31142.

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