"Cycloleucine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino acid formed by cyclization of leucine. It has cytostatic, immunosuppressive and antineoplastic activities.
| Descriptor ID |
D003515
|
| MeSH Number(s) |
D02.455.426.392.368.450.350 D12.125.072.170
|
| Concept/Terms |
Cycloleucine- Cycloleucine
- 1-Aminocyclopentanecarboxylic Acid
- 1 Aminocyclopentanecarboxylic Acid
- Acid, 1-Aminocyclopentanecarboxylic
- Aminocyclopentanecarboxylic Acid
- Acid, Aminocyclopentanecarboxylic
|
Below are MeSH descriptors whose meaning is more general than "Cycloleucine".
Below are MeSH descriptors whose meaning is more specific than "Cycloleucine".
This graph shows the total number of publications written about "Cycloleucine" by people in this website by year, and whether "Cycloleucine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cycloleucine" by people in Profiles.
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Winder DG, Conn PJ. Metabotropic glutamate receptor (mGluR)-mediated potentiation of cyclic AMP responses does not require phosphoinositide hydrolysis: mediation by a group II-like mGluR. J Neurochem. 1995 Feb; 64(2):592-9.
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Chung DS, Winder DG, Conn PJ. 4-Bromohomoibotenic acid selectively activates a 1-aminocyclopentane-1S,3R-dicarboxylic acid-insensitive metabotropic glutamate receptor coupled to phosphoinositide hydrolysis in rat cortical slices. J Neurochem. 1994 Jul; 63(1):133-9.
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Winder DG, Smith T, Conn PJ. Pharmacological differentiation of metabotropic glutamate receptors coupled to potentiation of cyclic adenosine monophosphate responses and phosphoinositide hydrolysis. J Pharmacol Exp Ther. 1993 Aug; 266(2):518-25.
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Winder DG, Conn PJ. Activation of metabotropic glutamate receptors increases cAMP accumulation in hippocampus by potentiating responses to endogenous adenosine. J Neurosci. 1993 Jan; 13(1):38-44.
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Winder DG, Conn PJ. Activation of metabotropic glutamate receptors in the hippocampus increases cyclic AMP accumulation. J Neurochem. 1992 Jul; 59(1):375-8.
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Prince DL, Kotin RM, Dubin DT. Evidence that the methylation inhibitor cycloleucine causes accumulation of a discrete ribosomal RNA precursor in hamster mitochondria. Mol Biol Rep. 1986; 11(1):51-5.