Comorbidity

"Comorbidity" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The presence of co-existing or additional diseases with reference to an initial diagnosis or with reference to the index condition that is the subject of study. Comorbidity may affect the ability of affected individuals to function and also their survival; it may be used as a prognostic indicator for length of hospital stay, cost factors, and outcome or survival.

Descriptor ID	D015897
MeSH Number(s)	N05.715.350.225 N06.850.490.687
Concept/Terms	Comorbidity Comorbidity Comorbidities

Below are MeSH descriptors whose meaning is more general than "Comorbidity".

Health Care [N]
Health Care Quality, Access, and Evaluation [N05]
Quality of Health Care [N05.715]
Epidemiologic Factors [N05.715.350]
Comorbidity [N05.715.350.225]
Environment and Public Health [N06]
Public Health [N06.850]
Epidemiologic Factors [N06.850.490]
Comorbidity [N06.850.490.687]

Below are MeSH descriptors whose meaning is related to "Comorbidity".

Below are MeSH descriptors whose meaning is more specific than "Comorbidity".

Comorbidity
Multimorbidity

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Comorbidity" by people in this website by year, and whether "Comorbidity" was a major or minor topic of these publications.

Bar chart showing 837 publications over 30 distinct years, with a maximum of 58 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	6	8
1997	0	8	8
1998	0	16	16
1999	0	6	6
2000	0	5	5
2001	0	7	7
2002	0	14	14
2003	1	23	24
2004	1	18	19
2005	0	27	27
2006	0	30	30
2007	1	36	37
2008	1	31	32
2009	0	37	37
2010	1	38	39
2011	0	37	37
2012	0	42	42
2013	0	42	42
2014	4	54	58
2015	2	47	49
2016	1	53	54
2017	0	45	45
2018	0	45	45
2019	2	38	40
2020	1	37	38
2021	1	25	26
2022	0	11	11
2023	0	10	10
2024	2	15	17
2025	0	14	14

Below are the most recent publications written about "Comorbidity" by people in Profiles.

Lee JA, Pakpahan R, Amante DJ, Gerber BS, Yang L. Comorbidity prevalence and incidence in cancer survivors: a longitudinal All of Us study. JNCI Cancer Spectr. 2025 Nov 03; 9(6).

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Gale CP, Hurst JR, Hawkins NM, Bourbeau J, Han MK, Lam CSP, Marciniuk DD, Price D, Stolz D, Gluckman T, Zieroth S, Nadarajah R, Young RP, Singh D, Martinez FJ, Berg DD, Bhutani M. Identification and management of cardiopulmonary risk in patients with chronic obstructive pulmonary disease: a multidisciplinary consensus and modified Delphi study. Eur J Prev Cardiol. 2025 Oct 28; 32(15):1445-1460.

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Elmoursi A, DiGiacomo DV, Farmer JR, Barmettler S. Hepatic Manifestations in Common Variable Immunodeficiency Associated With Mortality and Worse Hospital Outcomes in Nationwide Analysis Using National Readmission Database. J Allergy Clin Immunol Pract. 2025 Nov; 13(11):3118-3128.e3.

View in: PubMed
Sinha P, Karoly M, Padmapriyadarsini C, Paradkar M, Mave V, Gupte N, Gupta A, Dauphinais M, Babu SP, Gaikwad S, Cox SR, Golub J, Cintron C, Thangakunam B, Ezhumalai K, Ponnuraja C, Tornheim JA, Christopher DJ, Viswanathan V, Ellner JJ, Kornfeld H, Horsburgh CR, Shivakumar SVBY, Salgame P, Bollinger RC, Sarkar S, Gupte AN. Contribution of Key Comorbidities to Unfavorable Treatment Outcomes Among Adults With Drug-Sensitive Pulmonary TB in India: A Prospective Cohort Analysis. Chest. 2026 Jan; 169(1):64-72.

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Kim J, Kim B, Han KD, Kwon S, Shin DW, Min JH. Risk of depression in chronic immune-mediated neuropathies: A nationwide cohort study in South Korea. J Affect Disord. 2026 Jan 01; 392:120204.

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Oyinbo AG, Tisminetzky M, Baek J, Castaneda-Avila MA, DuMontier C, Ramanathan M, Lapane KL, Epstein MM. Patterns of multimorbidity in older adults with multiple myeloma: An analysis of SEER-Medicare. PLoS One. 2025; 20(8):e0330331.

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Karsberg S, Najavits L, Pedersen MU, Elklit A, Vang ML. Trauma and ICD-11 PTSD in substance use disorder treatment: a Danish multi-site study. BMC Psychiatry. 2025 Aug 07; 25(1):770.

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Choi H, Han K, Jung JH, De Soyza A, Kim H, Shin DW, Lee H. Impact of rheumatoid arthritis, seropositivity and disease-modifying anti-rheumatic drugs on mortality risk in bronchiectasis. Ther Adv Respir Dis. 2025 Jan-Dec; 19:17534666251360071.

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Helm A, Kachadoorian E, Shaffer PM, Hall OT, Smelson D. Clinical Characteristics of Patients With and Without Chronic Pain Seeking Behavioral Health Treatment for Co-Occurring Opioid Use and Mental Health Disorders. Subst Use Addctn J. 2026 Jan; 47(1):179-185.

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Yang Y, Br?nn E, Zhou J, Wei D, Bergstedt J, Fang F, Valdimarsd?ttir UA, Bertone-Johnson E, Lu D. Premenstrual disorders and risk of cardiovascular diseases. Nat Cardiovasc Res. 2025 Aug; 4(8):1001-1010.

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