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John Mordes to Rats, Inbred BB

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This is a "connection" page, showing publications John Mordes has written about Rats, Inbred BB.
John Mordes
Connection Strength
1.575
Rats, Inbred BB
  1. Blankenhorn EP, Rodemich L, Martin-Fernandez C, Leif J, Greiner DL, Mordes JP. The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection. Diabetes. 2005 Apr; 54(4):1233-7.
    View in: PubMed
    Score: 0.234
  2. Mordes JP, Bortell R, Blankenhorn EP, Rossini AA, Greiner DL. Rat models of type 1 diabetes: genetics, environment, and autoimmunity. ILAR J. 2004; 45(3):278-91.
    View in: PubMed
    Score: 0.215
  3. Mordes JP, Bortell R, Doukas J, Rigby M, Whalen B, Zipris D, Greiner DL, Rossini AA. The BB/Wor rat and the balance hypothesis of autoimmunity. Diabetes Metab Rev. 1996 Jul; 12(2):103-9.
    View in: PubMed
    Score: 0.128
  4. Mordes JP, Desemone J, Rossini AA. The BB rat. Diabetes Metab Rev. 1987 Jul; 3(3):725-50.
    View in: PubMed
    Score: 0.069
  5. Whalen BJ, Mordes JP, Rossini AA. The BB rat as a model of human insulin-dependent diabetes mellitus. Curr Protoc Immunol. 2001 May; Chapter 15:15.3.1-15.3.15.
    View in: PubMed
    Score: 0.045
  6. Bogdani M, Faxius L, Fex M, Ramelius A, Wernersson A, Mordes JP, Blankenhorn EP, Lernmark ?. The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats. Front Endocrinol (Lausanne). 2021; 12:629242.
    View in: PubMed
    Score: 0.044
  7. Martin AM, Maxson MN, Leif J, Mordes JP, Greiner DL, Blankenhorn EP. Diabetes-prone and diabetes-resistant BB rats share a common major diabetes susceptibility locus, iddm4: additional evidence for a "universal autoimmunity locus" on rat chromosome 4. Diabetes. 1999 Nov; 48(11):2138-44.
    View in: PubMed
    Score: 0.040
  8. Iwakoshi NN, Greiner DL, Rossini AA, Mordes JP. Diabetes prone BB rats are severely deficient in natural killer T cells. Autoimmunity. 1999; 31(1):1-14.
    View in: PubMed
    Score: 0.038
  9. Doukas J, Majno G, Mordes JP. Anti-endothelial cell autoantibodies in BB rats with spontaneous and induced IDDM. Diabetes. 1996 Sep; 45(9):1209-16.
    View in: PubMed
    Score: 0.032
  10. Mordes JP, Schirf B, Roipko D, Greiner DL, Weiner H, Nelson P, Rossini AA. Oral insulin does not prevent insulin-dependent diabetes mellitus in BB rats. Ann N Y Acad Sci. 1996 Feb 13; 778:418-21.
    View in: PubMed
    Score: 0.031
  11. Rossini AA, Handler ES, Mordes JP, Greiner DL. Human autoimmune diabetes mellitus: lessons from BB rats and NOD mice--Caveat emptor. Clin Immunol Immunopathol. 1995 Jan; 74(1):2-9.
    View in: PubMed
    Score: 0.029
  12. Doukas J, Cutler AH, Mordes JP. Polyinosinic:polycytidylic acid is a potent activator of endothelial cells. Am J Pathol. 1994 Jul; 145(1):137-47.
    View in: PubMed
    Score: 0.028
  13. Cris? L, Sarkar P, Waite DJ, Friedrich FH, Rajan TV, Mordes JP, Handler ES, Thiele HG, Rossini AA, et al. An RT6a gene is transcribed and translated in lymphopenic diabetes-prone BB rats. Diabetes. 1993 May; 42(5):688-95.
    View in: PubMed
    Score: 0.026
  14. Kitagawa Y, Desemone J, Mordes JP. Pancreas-specific venular labeling by monastral blue B in the BB rat: modulation by prostaglandins and their inhibitors. Immunopharmacology. 1993 May-Jun; 25(3):229-38.
    View in: PubMed
    Score: 0.026
  15. Cris? L, Mordes JP, Rossini AA. Autoimmune diabetes mellitus in the BB rat. Diabetes Metab Rev. 1992 Apr; 8(1):4-37.
    View in: PubMed
    Score: 0.024
  16. Thomas VA, Woda BA, Handler ES, Greiner DL, Mordes JP, Rossini AA. Altered expression of diabetes in BB/Wor rats by exposure to viral pathogens. Diabetes. 1991 Feb; 40(2):255-8.
    View in: PubMed
    Score: 0.022
  17. Rossini AA, Handler ES, Greiner DL, Mordes JP. Insulin dependent diabetes mellitus hypothesis of autoimmunity. Autoimmunity. 1991; 8(3):221-35.
    View in: PubMed
    Score: 0.022
  18. Kaldunski M, Jia S, Geoffrey R, Basken J, Prosser S, Kansra S, Mordes JP, Lernmark A, Wang X, Hessner MJ. Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat. Diabetes. 2010 Oct; 59(10):2375-85.
    View in: PubMed
    Score: 0.021
  19. Markholst H, Klaff LJ, Kl?ppel G, Lernmark A, Mordes JP, Palmer J. Lack of systematically found insulin autoantibodies in spontaneously diabetic BB rats. Diabetes. 1990 Jun; 39(6):720-7.
    View in: PubMed
    Score: 0.021
  20. Angelillo M, Greiner DL, Mordes JP, Handler ES, Nakamura N, McKeever U, Rossini A. Absence of RT6+ T cells in diabetes-prone biobreeding/Worcester rats is due to genetic and cell developmental defects. J Immunol. 1988 Dec 15; 141(12):4146-51.
    View in: PubMed
    Score: 0.019
  21. Gottlieb PA, Rossini AA, Mordes JP. Approaches to prevention and treatment of IDDM in animal models. Diabetes Care. 1988 Nov-Dec; 11 Suppl 1:29-36.
    View in: PubMed
    Score: 0.019
  22. Wallis RH, Wang K, Dabrowski D, Marandi L, Ning T, Hsieh E, Paterson AD, Mordes JP, Blankenhorn EP, Poussier P. A novel susceptibility locus on rat chromosome 8 affects spontaneous but not experimentally induced type 1 diabetes. Diabetes. 2007 Jun; 56(6):1731-6.
    View in: PubMed
    Score: 0.017
  23. Greiner DL, Mordes JP, Handler ES, Nakamura N, Angelillo M, Rossini AA. Prothymocyte development in diabetes-prone BB rats: description of a defect that predisposes to immune abnormalities. Transplant Proc. 1987 Feb; 19(1 Pt 2):976-8.
    View in: PubMed
    Score: 0.017
  24. Mordes JP, Gallina DL, Handler ES, Greiner DL, Nakamura N, Pelletier A, Rossini AA. Transfusions enriched for W3/25+ helper/inducer T lymphocytes prevent spontaneous diabetes in the BB/W rat. Diabetologia. 1987 Jan; 30(1):22-6.
    View in: PubMed
    Score: 0.017
  25. Hillebrands JL, Whalen B, Visser JT, Koning J, Bishop KD, Leif J, Rozing J, Mordes JP, Greiner DL, Rossini AA. A regulatory CD4+ T cell subset in the BB rat model of autoimmune diabetes expresses neither CD25 nor Foxp3. J Immunol. 2006 Dec 01; 177(11):7820-32.
    View in: PubMed
    Score: 0.016
  26. Mordes JP, Handler ES, Like AA, Nakano K, Rossini AA. Irradiated lymphocytes do not adoptively transfer diabetes or prevent spontaneous disease in the BB/W rat. Metabolism. 1986 Jun; 35(6):552-4.
    View in: PubMed
    Score: 0.016
  27. Beaudette-Zlatanova BC, Whalen B, Zipris D, Yagita H, Rozing J, Groen H, Benjamin CD, Hunig T, Drexhage HA, Ansari MJ, Leif J, Mordes JP, Greiner DL, Sayegh MH, Rossini AA. Costimulation and autoimmune diabetes in BB rats. Am J Transplant. 2006 May; 6(5 Pt 1):894-902.
    View in: PubMed
    Score: 0.016
  28. Greiner DL, Handler ES, Nakano K, Mordes JP, Rossini AA. Absence of the RT-6 T cell subset in diabetes-prone BB/W rats. J Immunol. 1986 Jan; 136(1):148-51.
    View in: PubMed
    Score: 0.015
  29. Malhotra A, Mordes JP, McDermott L, Schaible TF. Abnormal cardiac biochemistry in spontaneously diabetic Bio-Breeding/Worcester rat. Am J Physiol. 1985 Nov; 249(5 Pt 2):H1051-5.
    View in: PubMed
    Score: 0.015
  30. Handler ES, Mordes JP, Seals J, Koevary S, Like AA, Nakano K, Rossini AA. Diabetes in the Bio-Breeding/Worcester rat. Induction and acceleration by spleen cell-conditioned media. J Clin Invest. 1985 Oct; 76(4):1692-4.
    View in: PubMed
    Score: 0.015
  31. Todd DJ, Forsberg EM, Greiner DL, Mordes JP, Rossini AA, Bortell R. Deficiencies in gut NK cell number and function precede diabetes onset in BB rats. J Immunol. 2004 May 01; 172(9):5356-62.
    View in: PubMed
    Score: 0.014
  32. Hornum L, DeScipio C, Markholst H, Troutman SA, Novak S, Leif J, Greiner D, Mordes JP, Blankenhorn EP. Comparative mapping of rat Iddm4 to segments on HSA7 and MMU6. Mamm Genome. 2004 Jan; 15(1):53-61.
    View in: PubMed
    Score: 0.013
  33. Zipris D, Hillebrands JL, Welsh RM, Rozing J, Xie JX, Mordes JP, Greiner DL, Rossini AA. Infections that induce autoimmune diabetes in BBDR rats modulate CD4+CD25+ T cell populations. J Immunol. 2003 Apr 01; 170(7):3592-602.
    View in: PubMed
    Score: 0.013
  34. Bortell R, Moss J, McKenna RC, Rigby MR, Niedzwiecki D, Stevens LA, Patton WA, Mordes JP, Greiner DL, Rossini AA. Nicotinamide adenine dinucleotide (NAD) and its metabolites inhibit T lymphocyte proliferation: role of cell surface NAD glycohydrolase and pyrophosphatase activities. J Immunol. 2001 Aug 15; 167(4):2049-59.
    View in: PubMed
    Score: 0.011
  35. Whalen BJ, Marounek J, Weiser P, Appel MC, Greiner DL, Mordes JP, Rossini AA. BB rat thymocytes cultured in the presence of islets lose their ability to transfer autoimmune diabetes. Diabetes. 2001 May; 50(5):972-9.
    View in: PubMed
    Score: 0.011
  36. Bortel R, Waite DJ, Whalen BJ, Todd D, Leif JH, Lesma E, Moss J, Mordes JP, Rossini AA, Greiner DL. Levels of Art2+ cells but not soluble Art2 protein correlate with expression of autoimmune diabetes in the BB rat. Autoimmunity. 2001 May; 33(3):199-211.
    View in: PubMed
    Score: 0.011
  37. Zipris D, Leif J, Deluca D, Lin MY, Mordes JP, Rossini AA, Greiner DL, Whalen BJ. Fetal thymi from diabetes-prone but not diabetes-resistant BB/Wor rats fail to generate mature ART2+ T-cells in organ culture. Cell Mol Biol (Noisy-le-grand). 2001 Feb; 47(1):65-74.
    View in: PubMed
    Score: 0.011
  38. Whalen BJ, Love LC, Mordes JP, Rossini AA, Greiner DL. Intravital dye-labeled diabetogenic rat T cells retain dye, home to the pancreas, and induce diabetes. Transplant Proc. 1999 May; 31(3):1611-4.
    View in: PubMed
    Score: 0.010
  39. Whalen BJ, Weiser P, Marounek J, Rossini AA, Mordes JP, Greiner DL. Recapitulation of normal and abnormal BioBreeding rat T cell development in adult thymus organ culture. J Immunol. 1999 Apr 01; 162(7):4003-12.
    View in: PubMed
    Score: 0.010
  40. Martin AM, Blankenhorn EP, Maxson MN, Zhao M, Leif J, Mordes JP, Greiner DL. Non-major histocompatibility complex-linked diabetes susceptibility loci on chromosomes 4 and 13 in a backcross of the DP-BB/Wor rat to the WF rat. Diabetes. 1999 Jan; 48(1):50-8.
    View in: PubMed
    Score: 0.010
  41. Lesma E, Moss J, Brewer HB, Bortell R, Greiner D, Mordes J, Rossini AA. Characterization of high density lipoprotein-bound and soluble RT6 released following administration of anti-RT6.1 monoclonal antibody. J Immunol. 1998 Aug 01; 161(3):1212-9.
    View in: PubMed
    Score: 0.009
  42. Iwakoshi NN, Goldschneider I, Tausche F, Mordes JP, Rossini AA, Greiner DL. High frequency apoptosis of recent thymic emigrants in the liver of lymphopenic diabetes-prone BioBreeding rats. J Immunol. 1998 Jun 15; 160(12):5838-50.
    View in: PubMed
    Score: 0.009
  43. Malkani S, Nompleggi D, Hansen JW, Greiner DL, Mordes JP, Rossini AA. Dietary cow's milk protein does not alter the frequency of diabetes in the BB rat. Diabetes. 1997 Jul; 46(7):1133-40.
    View in: PubMed
    Score: 0.009
  44. Whalen BJ, Doukas J, Mordes JP, Rossini AA, Greiner DL. Induction of insulin-dependent diabetes mellitus in PVG.RT1u rats. Transplant Proc. 1997 May; 29(3):1684-5.
    View in: PubMed
    Score: 0.008
  45. Greiner DL, Malkani S, Kanaitsuka T, Bortell R, Doukas J, Rigby M, Whalen B, Stevens LA, Moss J, Mordes JP, Rossini AA. The T cell marker RT6 in a rat model of autoimmune diabetes. Adv Exp Med Biol. 1997; 419:209-16.
    View in: PubMed
    Score: 0.008
  46. Rigby MR, Bortell R, Greiner DL, Czech MP, Klarlund JK, Mordes JP, Rossini AA. The rat T-cell surface protein RT6 is associated with src family tyrosine kinases and generates an activation signal. Diabetes. 1996 Oct; 45(10):1419-26.
    View in: PubMed
    Score: 0.008
  47. Rigby MR, Bortell R, Stevens LA, Moss J, Kanaitsuka T, Shigeta H, Mordes JP, Greiner DL, Rossini AA. Rat RT6.2 and mouse Rt6 locus 1 are NAD+: arginine ADP ribosyltransferases with auto-ADP ribosylation activity. J Immunol. 1996 Jun 01; 156(11):4259-65.
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    Score: 0.008
  48. Waite DJ, Appel MC, Handler ES, Mordes JP, Rossini AA, Greiner DL. Ontogeny and immunohistochemical localization of thymus-dependent and thymus-independent RT6+ cells in the rat. Am J Pathol. 1996 Jun; 148(6):2043-56.
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    Score: 0.008
  49. Zipris D, Greiner DL, Malkani S, Whalen B, Mordes JP, Rossini AA. Cytokine gene expression in islets and thyroids of BB rats. IFN-gamma and IL-12p40 mRNA increase with age in both diabetic and insulin-treated nondiabetic BB rats. J Immunol. 1996 Feb 01; 156(3):1315-21.
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    Score: 0.008
  50. Whalen BJ, Rossini AA, Mordes JP, Greiner DL. DR-BB rat thymus contains thymocyte populations predisposed to autoreactivity. Diabetes. 1995 Aug; 44(8):963-7.
    View in: PubMed
    Score: 0.007
  51. Whalen BJ, Greiner DL, Mordes JP, Rossini AA. Adoptive transfer of autoimmune diabetes mellitus to athymic rats: synergy of CD4+ and CD8+ T cells and prevention by RT6+ T cells. J Autoimmun. 1994 Dec; 7(6):819-31.
    View in: PubMed
    Score: 0.007
  52. Doukas J, Mordes JP, Swymer C, Niedzwiecki D, Mason R, Rozing J, Rossini AA, Greiner DL. Thymic epithelial defects and predisposition to autoimmune disease in BB rats. Am J Pathol. 1994 Dec; 145(6):1517-25.
    View in: PubMed
    Score: 0.007
  53. Battan R, Mordes JP, Abreau S, Greiner DL, Handler ES, Rossini AA. Evidence that intrathymic islet transplantation does not prevent diabetes or subsequent islet graft destruction in RT6-depleted, diabetes-resistant BioBreeding/Worcester rats. Transplantation. 1994 Mar 15; 57(5):731-6.
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    Score: 0.007
  54. Sarkar P, Cris? L, McKeever U, Bortell R, Handler E, Mordes JP, Waite D, Schoenbaum A, Haag F, Koch-Nolte F, et al. Loss of RT6 message and most circulating T cells after thymectomy of diabetes prone BB rats. Autoimmunity. 1994; 18(1):15-22.
    View in: PubMed
    Score: 0.007
  55. Jiang Z, Makowiecki J, Mordes JP, Woda BA. Cytolysin gene expression in the islets of diabetic BioBreeding/Worcester rats. J Immunol. 1994 Jan 01; 152(1):322-9.
    View in: PubMed
    Score: 0.007
  56. Waite DJ, Handler ES, Mordes JP, Rossini AA, Greiner DL. The RT6 rat lymphocyte alloantigen circulates in soluble form. Cell Immunol. 1993 Nov; 152(1):82-95.
    View in: PubMed
    Score: 0.007
  57. Tafuri A, Bowers WE, Handler ES, Appel M, Lew R, Greiner D, Mordes JP, Rossini AA. High stimulatory activity of dendritic cells from diabetes-prone BioBreeding/Worcester rats exposed to macrophage-derived factors. J Clin Invest. 1993 May; 91(5):2040-8.
    View in: PubMed
    Score: 0.006
  58. Gottlieb PA, Handler ES, Appel MC, Greiner DL, Mordes JP, Rossini AA. Insulin treatment prevents diabetes mellitus but not thyroiditis in RT6-depleted diabetes resistant BB/Wor rats. Diabetologia. 1991 May; 34(5):296-300.
    View in: PubMed
    Score: 0.006
  59. Woda BA, Handler ES, Greiner DL, Reynolds C, Mordes JP, Rossini AA. T-lymphocyte requirement for diabetes in RT6-depleted diabetes-resistant BB rats. Diabetes. 1991 Apr; 40(4):423-8.
    View in: PubMed
    Score: 0.006
  60. McKeever U, Mordes JP, Greiner DL, Appel MC, Rozing J, Handler ES, Rossini AA. Adoptive transfer of autoimmune diabetes and thyroiditis to athymic rats. Proc Natl Acad Sci U S A. 1990 Oct; 87(19):7618-22.
    View in: PubMed
    Score: 0.005
  61. Abend S, Cormier J, Appel MC, Lueprasitsakul W, Alex S, Mordes JP, Usadel KH, Handler ES, Rossini AA, Braverman LE. The effect of ciamexone on lymphocytic thyroiditis and insulin-dependent diabetes mellitus in the BB/Wor rat. Immunopharmacology. 1990 May-Jun; 19(3):163-8.
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    Score: 0.005
  62. Lefkowith J, Schreiner G, Cormier J, Handler ES, Driscoll HK, Greiner D, Mordes JP, Rossini AA. Prevention of diabetes in the BB rat by essential fatty acid deficiency. Relationship between physiological and biochemical changes. J Exp Med. 1990 Mar 01; 171(3):729-43.
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    Score: 0.005
  63. Driscoll HK, Gottlieb PA, Mordes JP, Matschinsky FM, Rossini AA. Plasma from BB/Wor rats increases insulin secretion by perfused rat pancreas. Endocrinology. 1990 Feb; 126(2):1241-9.
    View in: PubMed
    Score: 0.005
  64. Handler ES, Mordes JP, McKeever U, Nakamura N, Bernhard J, Greiner DL, Rossini AA. Effects of irradiation on diabetes in the BB/Wor rat. Autoimmunity. 1989; 4(1-2):21-30.
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    Score: 0.005
  65. Rossini AA, Mordes JP, Greiner DL. The pathogenesis of autoimmune diabetes mellitus. Curr Opin Immunol. 1989-1990 Apr; 2(4):598-603.
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    Score: 0.005
  66. Greiner DL, Angelillo M, Mordes JP, Handler ES, Mojcik CF, Nakamura N, Rossini AA. Regulatory T cell control of autoimmune destruction of beta cells in the BB rat. Adv Exp Med Biol. 1988; 246:379-85.
    View in: PubMed
    Score: 0.004
  67. Greiner DL, Mordes JP, Handler ES, Angelillo M, Nakamura N, Rossini AA. Depletion of RT6.1+ T lymphocytes induces diabetes in resistant biobreeding/Worcester (BB/W) rats. J Exp Med. 1987 Aug 01; 166(2):461-75.
    View in: PubMed
    Score: 0.004
  68. Burstein D, Handler ES, Schindler J, Seals J, Mordes JP, Rossini AA. Effect of interleukin-2 on diabetes in the BB/Wor rat. Diabetes Res. 1987 Aug; 5(4):163-7.
    View in: PubMed
    Score: 0.004
Connection Strength

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Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.