Rats, Inbred BB

"Rats, Inbred BB" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A strain of Rattus norvegicus which is a model for spontaneous insulin-dependent diabetes mellitus (DIABETES MELLITUS, INSULIN-DEPENDENT).

Descriptor ID	D011913
MeSH Number(s)	B01.050.050.199.520.760.090 B01.050.150.900.649.313.992.635.505.700.400.090
Concept/Terms	Rats, Inbred BB Rats, Inbred BB BB Rat, Inbred BB Rats, Inbred Inbred BB Rat Inbred BB Rats Rat, Inbred BB Rats, BB BB Rat BB Rats Rat, BB BB Wistar Rats Rats, BB Wistar Wistar Rats, BB Bio-Breeding Inbred Rats Bio Breeding Inbred Rats Bio-Breeding Inbred Rat Inbred Rat, Bio-Breeding Inbred Rats, Bio-Breeding Rat, Bio-Breeding Inbred Rats, Bio-Breeding Inbred

Below are MeSH descriptors whose meaning is more general than "Rats, Inbred BB".

Organisms [B]
Eukaryota [B01]
Animals [B01.050]
Animal Population Groups [B01.050.050]
Animals, Laboratory [B01.050.050.199]
Animals, Inbred Strains [B01.050.050.199.520]
Rats, Inbred Strains [B01.050.050.199.520.760]
Rats, Inbred BB [B01.050.050.199.520.760.090]
Chordata [B01.050.150]
Vertebrates [B01.050.150.900]
Mammals [B01.050.150.900.649]
Eutheria [B01.050.150.900.649.313]
Rodentia [B01.050.150.900.649.313.992]
Muridae [B01.050.150.900.649.313.992.635]
Murinae [B01.050.150.900.649.313.992.635.505]
Rats [B01.050.150.900.649.313.992.635.505.700]
Rats, Inbred Strains [B01.050.150.900.649.313.992.635.505.700.400]
Rats, Inbred BB [B01.050.150.900.649.313.992.635.505.700.400.090]

Below are MeSH descriptors whose meaning is related to "Rats, Inbred BB".

Below are MeSH descriptors whose meaning is more specific than "Rats, Inbred BB".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Rats, Inbred BB" by people in this website by year, and whether "Rats, Inbred BB" was a major or minor topic of these publications.

Bar chart showing 41 publications over 15 distinct years, with a maximum of 8 publications in 1996

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	1	2
1996	1	7	8
1997	0	4	4
1998	0	3	3
1999	1	4	5
2001	1	5	6
2003	0	1	1
2004	1	2	3
2005	1	0	1
2006	0	2	2
2007	0	1	1
2009	0	1	1
2010	0	2	2
2017	0	1	1
2021	0	1	1

Below are the most recent publications written about "Rats, Inbred BB" by people in Profiles.

Bogdani M, Faxius L, Fex M, Ramelius A, Wernersson A, Mordes JP, Blankenhorn EP, Lernmark ?. The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats. Front Endocrinol (Lausanne). 2021; 12:629242.

View in: PubMed
Filion TM, Skelly JD, Huang H, Greiner DL, Ayers DC, Song J. Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue. Stem Cell Res Ther. 2017 03 11; 8(1):65.

View in: PubMed
Bortell R, Yang C. The BB rat as a model of human type 1 diabetes. Methods Mol Biol. 2012; 933:31-44.

View in: PubMed
Kruger AJ, Yang C, Lipson KL, Pino SC, Leif JH, Hogan CM, Whalen BJ, Guberski DL, Lee Y, Unger RH, Greiner DL, Rossini AA, Bortell R. Leptin treatment confers clinical benefit at multiple stages of virally induced type 1 diabetes in BB rats. Autoimmunity. 2011 Mar; 44(2):137-48.

View in: PubMed
Kaldunski M, Jia S, Geoffrey R, Basken J, Prosser S, Kansra S, Mordes JP, Lernmark A, Wang X, Hessner MJ. Identification of a serum-induced transcriptional signature associated with type 1 diabetes in the BioBreeding rat. Diabetes. 2010 Oct; 59(10):2375-85.

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Lien E, Zipris D. The role of Toll-like receptor pathways in the mechanism of type 1 diabetes. Curr Mol Med. 2009 Feb; 9(1):52-68.

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Wallis RH, Wang K, Dabrowski D, Marandi L, Ning T, Hsieh E, Paterson AD, Mordes JP, Blankenhorn EP, Poussier P. A novel susceptibility locus on rat chromosome 8 affects spontaneous but not experimentally induced type 1 diabetes. Diabetes. 2007 Jun; 56(6):1731-6.

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Hillebrands JL, Whalen B, Visser JT, Koning J, Bishop KD, Leif J, Rozing J, Mordes JP, Greiner DL, Rossini AA. A regulatory CD4+ T cell subset in the BB rat model of autoimmune diabetes expresses neither CD25 nor Foxp3. J Immunol. 2006 Dec 01; 177(11):7820-32.

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Beaudette-Zlatanova BC, Whalen B, Zipris D, Yagita H, Rozing J, Groen H, Benjamin CD, Hunig T, Drexhage HA, Ansari MJ, Leif J, Mordes JP, Greiner DL, Sayegh MH, Rossini AA. Costimulation and autoimmune diabetes in BB rats. Am J Transplant. 2006 May; 6(5 Pt 1):894-902.

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Blankenhorn EP, Rodemich L, Martin-Fernandez C, Leif J, Greiner DL, Mordes JP. The rat diabetes susceptibility locus Iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection. Diabetes. 2005 Apr; 54(4):1233-7.

View in: PubMed

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