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Impact of modifications of heterocyclic bases in CpG dinucleotides on their immune-modulatory activity.
Inhibitory oligonucleotides block the induction of AP-1 transcription factor by stimulatory CpG oligonucleotides in B cells.
Immunostimulatory potential of silencing RNAs can be mediated by a non-uridine-rich toll-like receptor 7 motif.
CpG oligodeoxynucleotides augment the murine immune response to the Yersinia pestis F1-V vaccine in bubonic and pneumonic models of plague.
Now I know my CpGs.
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Now I know my CpGs.
Krieg AM. Now I know my CpGs. Trends Microbiol. 2001 Jun; 9(6):249-52.
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PubMed
subject areas
Animals
Cell Division
CpG Islands
DNA, Bacterial
DNA-Binding Proteins
Endosomes
Humans
Receptors, Cell Surface
Toll-Like Receptor 9
authors with profiles
Arthur M Krieg MD