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Model systems for flavoenzyme activity. The effects of specific hydrogen bonds on the 13C and 1H NMR of flavins.
Pitch Perception
Multiple proteolytic events in caspase-6 self-activation impact conformations of discrete structural regions.
Allosteric inhibition of the NS2B-NS3 protease from dengue virus.
Caspase-9 CARD?:?core domain interactions require a properly formed active site.
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Caspase-9 CARD?:?core domain interactions require a properly formed active site.
Huber KL, Serrano BP, Hardy JA. Caspase-9 CARD?:?core domain interactions require a properly formed active site. Biochem J. 2018 03 29; 475(6):1177-1196.
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subject areas
Amino Acid Sequence
Amino Acid Substitution
Caspase 9
Caspase Activation and Recruitment Domain
Catalytic Domain
Enzyme Activation
Humans
Models, Molecular
Mutation, Missense
Protein Binding
Protein Folding
Protein Multimerization
authors with profiles
Jeanne A Hardy BS, PhD