Interleukin-1 Receptor-Like 1 Protein

"Interleukin-1 Receptor-Like 1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A receptor for INTERLEUKIN-33 that is related structurally to the interleukin-1 receptor. It contains three extracellular IMMUNOGLOBULIN-LIKE DOMAIN regions and associates with INTERLEUKIN-1 RECEPTOR ACCESSORY PROTEIN upon binding IL-33 to initiate signaling. It may function in the response of HELPER T CELLS to INFLAMMATION.

Descriptor ID	D000072179
MeSH Number(s)	D12.776.543.750.705.852.420.300.375
Concept/Terms	Interleukin-1 Receptor-Like 1 Protein Interleukin-1 Receptor-Like 1 Protein Interleukin 1 Receptor Like 1 Protein Interleukin 1 Receptor-Related Protein Interleukin 1 Receptor Related Protein Interleukin-33 Receptor Interleukin 33 Receptor Receptor, Interleukin-33 IL1RL1 Protein

Below are MeSH descriptors whose meaning is more general than "Interleukin-1 Receptor-Like 1 Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Membrane Proteins [D12.776.543]
Receptors, Cell Surface [D12.776.543.750]
Receptors, Immunologic [D12.776.543.750.705]
Receptors, Cytokine [D12.776.543.750.705.852]
Receptors, Interleukin [D12.776.543.750.705.852.420]
Receptors, Interleukin-1 [D12.776.543.750.705.852.420.300]
Interleukin-1 Receptor-Like 1 Protein [D12.776.543.750.705.852.420.300.375]

Below are MeSH descriptors whose meaning is related to "Interleukin-1 Receptor-Like 1 Protein".

Below are MeSH descriptors whose meaning is more specific than "Interleukin-1 Receptor-Like 1 Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Interleukin-1 Receptor-Like 1 Protein" by people in this website by year, and whether "Interleukin-1 Receptor-Like 1 Protein" was a major or minor topic of these publications.

Bar chart showing 7 publications over 5 distinct years, with a maximum of 2 publications in 2013 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2013	0	2	2
2015	0	1	1
2024	1	1	2
2025	1	0	1

Below are the most recent publications written about "Interleukin-1 Receptor-Like 1 Protein" by people in Profiles.

Krajewski D, Ranjitkar S, Jordan N, Schneider SS, Mathias CB. IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy. Front Immunol. 2025; 16:1526498.

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Ranjitkar S, Krajewski D, Tedeschi C, Perez NM, Jordan N, Gregory K, Schneider SS, Mathias CB. Mast cell responses in a mouse model of food allergy are regulated via a ST2/IL-4 axis. Allergy. 2024 Sep; 79(9):2561-2564.

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Ranjitkar S, Krajewski D, Garcia C, Tedeschi C, Polukort SH, Rovatti J, Mire M, Blesso CN, Jellison E, Schneider SS, Ryan JJ, Mathias CB. IL-10 Differentially Promotes Mast Cell Responsiveness to IL-33, Resulting in Enhancement of Type 2 Inflammation and Suppression of Neutrophilia. J Immunol. 2024 May 01; 212(9):1407-1419.

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Li S, Bostick JW, Ye J, Qiu J, Zhang B, Urban JF, Avram D, Zhou L. Aryl Hydrocarbon Receptor Signaling Cell Intrinsically Inhibits Intestinal Group 2 Innate Lymphoid Cell Function. Immunity. 2018 11 20; 49(5):915-928.e5.

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Kearley J, Silver JS, Sanden C, Liu Z, Berlin AA, White N, Mori M, Pham TH, Ward CK, Criner GJ, Marchetti N, Mustelin T, Erjefalt JS, Kolbeck R, Humbles AA. Cigarette smoke silences innate lymphoid cell function and facilitates an exacerbated type I interleukin-33-dependent response to infection. Immunity. 2015 Mar 17; 42(3):566-79.

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Rienstra M, Yin X, Larson MG, Fontes JD, Magnani JW, McManus DD, McCabe EL, Coglianese EE, Amponsah M, Ho JE, Januzzi JL, Wollert KC, Fradley MG, Vasan RS, Ellinor PT, Wang TJ, Benjamin EJ. Relation between soluble ST2, growth differentiation factor-15, and high-sensitivity troponin I and incident atrial fibrillation. Am Heart J. 2014 Jan; 167(1):109-115.e2.

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Ho JE, Chen WY, Chen MH, Larson MG, McCabe EL, Cheng S, Ghorbani A, Coglianese E, Emilsson V, Johnson AD, Walter S, Franceschini N, O'Donnell CJ, Dehghan A, Lu C, Levy D, Newton-Cheh C, Lin H, Felix JF, Schreiter ER, Vasan RS, Januzzi JL, Lee RT, Wang TJ. Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling. J Clin Invest. 2013 Oct; 123(10):4208-18.

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Brint EK, Fitzgerald KA, Smith P, Coyle AJ, Gutierrez-Ramos JC, Fallon PG, O'Neill LA. Characterization of signaling pathways activated by the interleukin 1 (IL-1) receptor homologue T1/ST2. A role for Jun N-terminal kinase in IL-4 induction. J Biol Chem. 2002 Dec 20; 277(51):49205-11.

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