Real-Time Polymerase Chain Reaction

"Real-Time Polymerase Chain Reaction" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Methods used for detecting the amplified DNA products from the polymerase chain reaction as they accumulate instead of at the end of the reaction.

Descriptor ID	D060888
MeSH Number(s)	E05.393.620.500.706
Concept/Terms	Real-Time Polymerase Chain Reaction Real-Time Polymerase Chain Reaction Real Time Polymerase Chain Reaction Real-Time PCR PCR, Real-Time PCRs, Real-Time Real Time PCR Real-Time PCRs Kinetic Polymerase Chain Reaction Kinetic Polymerase Chain Reaction Quantitative Real-Time Polymerase Chain Reaction Quantitative Real-Time Polymerase Chain Reaction Quantitative Real Time Polymerase Chain Reaction Quantitative Real-Time PCR PCR, Quantitative Real-Time PCRs, Quantitative Real-Time Quantitative Real Time PCR Quantitative Real-Time PCRs Real-Time PCR, Quantitative Real-Time PCRs, Quantitative

Below are MeSH descriptors whose meaning is more general than "Real-Time Polymerase Chain Reaction".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Nucleic Acid Amplification Techniques [E05.393.620]
Polymerase Chain Reaction [E05.393.620.500]
Real-Time Polymerase Chain Reaction [E05.393.620.500.706]

Below are MeSH descriptors whose meaning is related to "Real-Time Polymerase Chain Reaction".

Below are MeSH descriptors whose meaning is more specific than "Real-Time Polymerase Chain Reaction".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Real-Time Polymerase Chain Reaction" by people in this website by year, and whether "Real-Time Polymerase Chain Reaction" was a major or minor topic of these publications.

Bar chart showing 162 publications over 18 distinct years, with a maximum of 27 publications in 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2009	0	1	1
2010	0	1	1
2011	0	6	6
2012	0	21	21
2013	0	18	18
2014	0	27	27
2015	1	17	18
2016	1	22	23
2017	1	10	11
2018	3	4	7
2019	3	4	7
2020	3	6	9
2021	1	4	5
2022	0	3	3
2023	0	1	1
2024	0	1	1
2025	1	0	1
2026	2	0	2

Below are the most recent publications written about "Real-Time Polymerase Chain Reaction" by people in Profiles.

Pfefferle S, N?rz D, Giersch K, Grunwald M, Tang HT, Pfl?ger LS, L?tgehetmann M. Refined fully automated RT-qPCR assay for simultaneous detection of SARS-CoV-2, Influenza A/B, and RSV with target optimization for improved variant resilience. J Clin Virol. 2026 Apr; 183:105924.

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Panajotov J, Giersch K, Pfl?ger LS, N?rz D, Grunwald M, Tang HT, Kaiser M, Pischke S, Ulrich RG, Pfefferle S, Schulze Zur Wisch J, Corman VM, Aepfelbacher M, Johne R, L?tgehetmann M. Development of a Fully Automated, High-Throughput Molecular Assay for Detection of Rat Hepatitis E Virus in Routine Diagnostics. J Med Virol. 2026 Feb; 98(2):e70824.

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Giersch K, N?rz D, Grunwald M, Pfefferle S, Pfl?ger LS, Fischer N, Aepfelbacher M, L?tgehetmann M. Adaptation and validation of a gastrointestinal panel to detect diarrheal virus pathogens on a high-throughput qPCR system. Med Microbiol Immunol. 2025 Jun 03; 214(1):28.

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Xu G, Siegel E, Fernandez N, Bechtold E, Daly T, Dupuis AP, Ciota A, Rich SM. Active Surveillance of Powassan Virus in Massachusetts Ixodes scapularis Ticks, Comparing Detection Using a New Triplex Real-Time PCR Assay with a Luminex Vector-Borne Panel. Viruses. 2024 02 04; 16(2).

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Fran?ois R, Kashamuka MM, Banek K, Bala JA, Nkalani M, Kihuma G, Atibu J, Mahilu GE, Thwai KL, Assefa A, Bailey JA, Dinglasan RR, Juliano JJ, Tshefu AK, Parr JB. Plasmodium falciparum with pfhrp2/3 Deletion Not Detected in a 2018-2021 Malaria Longitudinal Cohort Study in Kinshasa Province, Democratic Republic of the Congo. Am J Trop Med Hyg. 2023 08 02; 109(2):273-276.

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Pratt GW, Platt M, Velez A, Rao LV. Utility of Whole Blood Real-Time PCR Testing for the Diagnosis of Early Lyme Disease. Am J Clin Pathol. 2022 09 02; 158(3):327-330.

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N?rz D, Brehm TT, Tang HT, Grewe I, Hermanussen L, Matthews H, Pestel J, Degen O, G?nther T, Grundhoff A, Fischer N, Addo MM, Jordan S, Hertling S, Unger S, Sch?fer G, Schewe K, Hoffmann C, Aepfelbacher M, Pfefferle S, Schulze Zur Wiesch J, Schmiedel S, L?tgehetmann M. Clinical characteristics and comparison of longitudinal qPCR results from different specimen types in a cohort of ambulatory and hospitalized patients infected with monkeypox virus. J Clin Virol. 2022 10; 155:105254.

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Xu G, Ribbe F, McCaffery J, Luo CY, Li AY, Rich SM. Development of a Taqman Real-Time PCR for the Identification of Haemaphysalis longicornis (Acari: Ixodidae). J Med Entomol. 2022 07 13; 59(4):1484-1487.

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Shin M, Meda Krishnamurthy P, Devi G, Watts JK. Quantification of Antisense Oligonucleotides by Splint Ligation and Quantitative Polymerase Chain Reaction. Nucleic Acid Ther. 2022 02; 32(1):66-73.

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Shenoy AT, Lyon De Ana C, Arafa EI, Salwig I, Barker KA, Korkmaz FT, Ramanujan A, Etesami NS, Soucy AM, Martin IMC, Tilton BR, Hinds A, Goltry WN, Kathuria H, Braun T, Jones MR, Quinton LJ, Belkina AC, Mizgerd JP. Antigen presentation by lung epithelial cells directs CD4+ TRM cell function and regulates barrier immunity. Nat Commun. 2021 10 05; 12(1):5834.

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