Healthy Volunteers

"Healthy Volunteers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Persons with no known significant health problems who are recruited to participate in research to test a new drug, device, or intervention as controls for a patient group. (from http://clinicalcenter.nih.gov/recruit/volunteers.html, accessed 2/14/2013)

Descriptor ID	D064368
MeSH Number(s)	M01.774.500 M01.955.236
Concept/Terms	Healthy Volunteers Healthy Volunteers Healthy Volunteer Volunteer, Healthy Healthy Participants Healthy Participant Participant, Healthy Participants, Healthy Healthy Subjects Healthy Subject Subject, Healthy Subjects, Healthy Human Volunteers Human Volunteers Human Volunteer Volunteer, Human Volunteers, Human Normal Volunteers Normal Volunteers Normal Volunteer Volunteer, Normal Volunteers, Normal

Below are MeSH descriptors whose meaning is more general than "Healthy Volunteers".

Named Groups [M]
Persons [M01]
Research Subjects [M01.774]
Healthy Volunteers [M01.774.500]
Volunteers [M01.955]
Healthy Volunteers [M01.955.236]

Below are MeSH descriptors whose meaning is related to "Healthy Volunteers".

Below are MeSH descriptors whose meaning is more specific than "Healthy Volunteers".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Healthy Volunteers" by people in this website by year, and whether "Healthy Volunteers" was a major or minor topic of these publications.

Bar chart showing 55 publications over 11 distinct years, with a maximum of 9 publications in 2021

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2013	3	3
2014	3	3
2015	5	5
2016	7	7
2017	6	6
2018	4	4
2019	7	7
2020	6	6
2021	9	9
2022	3	3
2025	2	2

Below are the most recent publications written about "Healthy Volunteers" by people in Profiles.

Sullivan-B?lyai JZ, Allen LB, Cannon R, Cohane KP, Dunzo E, Goldwater R, StCyr K, Wang Y, Klempner MS. A Phase 1 Study in Healthy Subjects to Evaluate the Safety and Pharmacokinetics of a Human Monoclonal Antibody (S315) Against Diphtheria Toxin. J Infect Dis. 2025 Sep 15; 232(3):534-539.

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Sakharkar M, Jalihal PK, Ramirez K, Karmali F, Lewis RF, Chari DA. Characterization of Optokinetic Nystagmus in Healthy Participants With a Novel Oculography Device. Otolaryngol Head Neck Surg. 2025 May; 172(5):1692-1702.

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Deligiannidis KM, Bullock A, Nandy I, Dunbar J, Lasser R, Witte M, Leclair B, Wald J. Zuranolone Concentrations in the Breast Milk of Healthy, Lactating Individuals: Results From a Phase 1 Open-Label Study. J Clin Psychopharmacol. 2024 Jul-Aug 01; 44(4):337-344.

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Plotnik D, Sager JE, Aryal M, Fanget MC, Peter A, Schmid MA, Cebrik D, Mogalian E, Boundy K, Yeh WW, Griffin P, Reyes M. A phase 1 study in healthy volunteers to investigate the safety, tolerability, and pharmacokinetics of VIR-2482: a monoclonal antibody for the prevention of severe influenza A illness. Antimicrob Agents Chemother. 2024 04 03; 68(4):e0127323.

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Yadlapati R, Gyawali CP, Carlson DA, Pandolfino JE, Fass R, Khan A, Lin H, Richter JE, Vela MF, Vaezi M, Clarke JO. Inter- and intra-rater agreement of interpretation of functional lumen imaging probe in healthy subjects. Neurogastroenterol Motil. 2023 03; 35(3):e14505.

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Wald J, Henningsson A, Hanze E, Hoffmann E, Li H, Colquhoun H, Deligiannidis KM. Allopregnanolone Concentrations in Breast Milk and Plasma from Healthy Volunteers Receiving Brexanolone Injection, With Population Pharmacokinetic Modeling of Potential Relative Infant Dose. Clin Pharmacokinet. 2022 09; 61(9):1307-1319.

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Dsouza M, Menon R, Crossette E, Bhattarai SK, Schneider J, Kim YG, Reddy S, Caballero S, Felix C, Cornacchione L, Hendrickson J, Watson AR, Minot SS, Greenfield N, Schopf L, Szabady R, Patarroyo J, Smith W, Harrison P, Kuijper EJ, Kelly CP, Olle B, Bobilev D, Silber JL, Bucci V, Roberts B, Faith J, Norman JM. Colonization of the live biotherapeutic product VE303 and modulation of the microbiota and metabolites in healthy volunteers. Cell Host Microbe. 2022 04 13; 30(4):583-598.e8.

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Fierle JK, Abram-Saliba J, Atsaves V, Brioschi M, de Tiani M, Reichenbach P, Irving M, Coukos G, Dunn SM. A cell-based phenotypic library selection and screening approach for the de novo discovery of novel functional chimeric antigen receptors. Sci Rep. 2022 01 21; 12(1):1136.

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Hidalgo D, Bejder J, Pop R, Gellatly K, Hwang Y, Maxwell Scalf S, Eastman AE, Chen JJ, Zhu LJ, Heuberger JAAC, Guo S, Koury MJ, Nordsborg NB, Socolovsky M. EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis. Nat Commun. 2021 12 17; 12(1):7334.

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Massart J, Sj?gren RJO, Egan B, Garde C, Lindgren M, Gu W, Ferreira DMS, Katayama M, Ruas JL, Barr?s R, O'Gorman DJ, Zierath JR, Krook A. Endurance exercise training-responsive miR-19b-3p improves skeletal muscle glucose metabolism. Nat Commun. 2021 10 12; 12(1):5948.

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