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A multipronged approach for compiling a global map of allosteric regulation in the apoptotic caspases.
Caspases promote cell proliferation after necrosis.
In Vitro Cleavage Assays using Purified Recombinant Drosophila Caspases for Substrate Screening.
Multiple Mechanisms of Zinc-Mediated Inhibition for the Apoptotic Caspases-3, -6, -7, and -8.
The unconventional myosin CRINKLED and its mammalian orthologue MYO7A regulate caspases in their signalling roles.
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In Vitro Cleavage Assays using Purified Recombinant Drosophila Caspases for Substrate Screening.
Yarikipati P, Bergmann A. In Vitro Cleavage Assays using Purified Recombinant Drosophila Caspases for Substrate Screening. J Vis Exp. 2022 10 06; (188).
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PubMed
subject areas
Animals
Apoptosis
Caspases
Drosophila
Drosophila Proteins
Mammals
Proteolysis
Recombinant Proteins
authors with profiles
Andreas Bergmann PhD