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Gianluca Toraldo MD, PhD

TitleAssistant Professor
InstitutionUMass Chan Medical School
DepartmentMedicine at UMass Chan - Lahey
AddressLahey Regional Campus
41 Mall Road
Burlington MA 01805
Phone781-744-2088
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentMedicine at UMass Chan - Lahey


    Collapse Biography 
    Collapse education and training
    University of Perugia Medical School, Perugia, , ItalyMD
    University of Perugia Medical School, Perugia, , ItalyPHDEndocrinology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Guan H, Toraldo G, Godley FA, Rao SR, Cerda S, McAneny D, Doherty G, Lee SL. The real-world performance of ThyroSeqV.2 to diagnose thyroid "neoplasm requiring surgery". Am J Cancer Res. 2020; 10(11):3838-3851. PMID: 33294271.
      Citations:    
    2. Fazeli SR, Zehr B, Amraei R, Toraldo G, Guan H, Kindelberger D, Lee S, Cerda S. ThyroSeq v2 Testing: Impact on Cytologic Diagnosis, Management, and Cost of Care in Patients with Thyroid Nodule. Thyroid. 2020 10; 30(10):1528-1534. PMID: 32349630.
      Citations: 10     Fields:    Translation:Humans
    3. Guan H, Toraldo G, Cerda S, Godley FA, Rao SR, McAneny D, Doherty G, Braverman L, Lee SL. Utilities of RAS Mutations in Preoperative Fine Needle Biopsies for Decision Making for Thyroid Nodule Management: Results from a Single-Center Prospective Cohort. Thyroid. 2020 04; 30(4):536-547. PMID: 31996097.
      Citations: 19     Fields:    Translation:Humans
    4. Guan H, Matonis D, Toraldo G, Lee SL. Clinical Significance of Thyroid-Stimulating Hormone Receptor Gene Mutations and/or Sodium-Iodine Symporter Gene Overexpression in Indeterminate Thyroid Fine Needle Biopsies. Front Endocrinol (Lausanne). 2018; 9:566. PMID: 30319546.
      Citations: 6     Fields:    
    5. Guo W, Miller AD, Pencina K, Wong S, Lee A, Yee M, Toraldo G, Jasuja R, Bhasin S. Joint dysfunction and functional decline in middle age myostatin null mice. Bone. 2016 Feb; 83:141-148. PMID: 26549246.
      Citations: 3     Fields:    Translation:Animals
    6. Jasuja R, Costello JC, Singh R, Gupta V, Spina CS, Toraldo G, Jang H, Li H, Serra C, Guo W, Chauhan P, Narula NS, Guarneri T, Ergun A, Travison TG, Collins JJ, Bhasin S. Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy. Aging Cell. 2014 Apr; 13(2):303-10. PMID: 24305501.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    7. Serra C, Sandor NL, Jang H, Lee D, Toraldo G, Guarneri T, Wong S, Zhang A, Guo W, Jasuja R, Bhasin S. The effects of testosterone deprivation and supplementation on proteasomal and autophagy activity in the skeletal muscle of the male mouse: differential effects on high-androgen responder and low-androgen responder muscle groups. Endocrinology. 2013 Dec; 154(12):4594-606. PMID: 24105483.
      Citations: 29     Fields:    Translation:Animals
    8. DeFuria J, Belkina AC, Jagannathan-Bogdan M, Snyder-Cappione J, Carr JD, Nersesova YR, Markham D, Strissel KJ, Watkins AA, Zhu M, Allen J, Bouchard J, Toraldo G, Jasuja R, Obin MS, McDonnell ME, Apovian C, Denis GV, Nikolajczyk BS. B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile. Proc Natl Acad Sci U S A. 2013 Mar 26; 110(13):5133-8. PMID: 23479618.
      Citations: 251     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    9. Alamdari N, Toraldo G, Aversa Z, Smith I, Castillero E, Renaud G, Qaisar R, Larsson L, Jasuja R, Hasselgren PO. Loss of muscle strength during sepsis is in part regulated by glucocorticoids and is associated with reduced muscle fiber stiffness. Am J Physiol Regul Integr Comp Physiol. 2012 Nov 15; 303(10):R1090-9. PMID: 23019215.
      Citations: 11     Fields:    Translation:AnimalsCells
    10. Serra C, Tangherlini F, Rudy S, Lee D, Toraldo G, Sandor NL, Zhang A, Jasuja R, Bhasin S. Testosterone improves the regeneration of old and young mouse skeletal muscle. J Gerontol A Biol Sci Med Sci. 2013 Jan; 68(1):17-26. PMID: 22499765.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    11. Toraldo G, Bhasin S, Bakhit M, Guo W, Serra C, Safer JD, Bhawan J, Jasuja R. Topical androgen antagonism promotes cutaneous wound healing without systemic androgen deprivation by blocking ?-catenin nuclear translocation and cross-talk with TGF-? signaling in keratinocytes. Wound Repair Regen. 2012 Jan-Feb; 20(1):61-73. PMID: 22276587.
      Citations: 9     Fields:    Translation:AnimalsCells
    12. Ward JE, Ren R, Toraldo G, Soohoo P, Guan J, O'Hara C, Jasuja R, Trinkaus-Randall V, Liao R, Connors LH, Seldin DC. Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis. Blood. 2011 Dec 15; 118(25):6610-7. PMID: 21998211.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    13. Kumar R, Zakharov MN, Khan SH, Miki R, Jang H, Toraldo G, Singh R, Bhasin S, Jasuja R. The dynamic structure of the estrogen receptor. J Amino Acids. 2011; 2011:812540. PMID: 22312471.
      Citations:    
    14. Li Y, Toraldo G, Li A, Yang X, Zhang H, Qian WP, Weitzmann MN. B cells and T cells are critical for the preservation of bone homeostasis and attainment of peak bone mass in vivo. Blood. 2007 May 01; 109(9):3839-48. PMID: 17202317.
      Citations: 219     Fields:    Translation:AnimalsCells
    15. Gao Y, Qian WP, Dark K, Toraldo G, Lin AS, Guldberg RE, Flavell RA, Weitzmann MN, Pacifici R. Estrogen prevents bone loss through transforming growth factor beta signaling in T cells. Proc Natl Acad Sci U S A. 2004 Nov 23; 101(47):16618-23. PMID: 15531637.
      Citations: 53     Fields:    Translation:AnimalsCells
    16. Cenci S, Toraldo G, Weitzmann MN, Roggia C, Gao Y, Qian WP, Sierra O, Pacifici R. Estrogen deficiency induces bone loss by increasing T cell proliferation and lifespan through IFN-gamma-induced class II transactivator. Proc Natl Acad Sci U S A. 2003 Sep 02; 100(18):10405-10. PMID: 12923292.
      Citations: 118     Fields:    Translation:AnimalsCells
    17. Toraldo G, Roggia C, Qian WP, Pacifici R, Weitzmann MN. IL-7 induces bone loss in vivo by induction of receptor activator of nuclear factor kappa B ligand and tumor necrosis factor alpha from T cells. Proc Natl Acad Sci U S A. 2003 Jan 07; 100(1):125-30. PMID: 12490655.
      Citations: 98     Fields:    Translation:AnimalsCells
    18. Weitzmann MN, Roggia C, Toraldo G, Weitzmann L, Pacifici R. Increased production of IL-7 uncouples bone formation from bone resorption during estrogen deficiency. J Clin Invest. 2002 Dec; 110(11):1643-50. PMID: 12464669.
      Citations: 97     Fields:    Translation:AnimalsCells
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