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Long Cai PhD

TitleAdjunct Professor
InstitutionUMass Chan Medical School
DepartmentDermatology
AddressCalifornia Institute of Technology
1200 East California Boulevard, MC140-18
Pasadena CA 91125
Phone626-395-6570
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    Other Positions
    InstitutionT.H. Chan School of Medicine
    DepartmentDermatology


    Collapse Biography 
    Collapse education and training
    Harvard University, Cambridge, MA, United StatesBA
    Harvard University, Cambridge, MA, United StatesMA
    Harvard University, Cambridge, MA, United StatesPHD

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Takei Y, Yang Y, White J, Goronzy IN, Yun J, Prasad M, Ombelets LJ, Schindler S, Bhat P, Guttman M, Cai L. Spatial multi-omics reveals cell-type-specific nuclear compartments. Nature. 2025 May; 641(8064):1037-1047. PMID: 40205045.
      Citations:    
    2. Polonsky M, Gerhardt LMS, Yun J, Koppitch K, Col?n KL, Amrhein H, Wold B, Zheng S, Yuan GC, Thomson M, Cai L, McMahon AP. Spatial transcriptomics defines injury specific microenvironments and cellular interactions in kidney regeneration and disease. Nat Commun. 2024 09 05; 15(1):7010. PMID: 39237549.
      Citations:    
    3. Lohoff T, Ghazanfar S, Missarova A, Koulena N, Pierson N, Griffiths JA, Bardot ES, Eng CL, Tyser RCV, Argelaguet R, Guibentif C, Srinivas S, Briscoe J, Simons BD, Hadjantonakis AK, G?ttgens B, Reik W, Nichols J, Cai L, Marioni JC. Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis. Nat Biotechnol. 2022 01; 40(1):74-85. PMID: 34489600.
      Citations:    
    4. Dar D, Dar N, Cai L, Newman DK. Spatial transcriptomics of planktonic and sessile bacterial populations at single-cell resolution. Science. 2021 08 13; 373(6556). PMID: 34385369.
      Citations:    
    5. Takei Y, Yun J, Zheng S, Ollikainen N, Pierson N, White J, Shah S, Thomassie J, Suo S, Eng CL, Guttman M, Yuan GC, Cai L. Integrated spatial genomics reveals global architecture of single nuclei. Nature. 2021 02; 590(7845):344-350. PMID: 33505024.
      Citations:    
    6. Zhang Y, Sohn C, Lee S, Ahn H, Seo J, Cao J, Cai L. Author Correction: Detecting protein and post-translational modifications in single cells with iDentification and qUantification sEparaTion (DUET). Commun Biol. 2020 Aug 18; 3(1):463. PMID: 32811971.
      Citations:    
    7. Zhang Y, Sohn C, Lee S, Ahn H, Seo J, Cao J, Cai L. Detecting protein and post-translational modifications in single cells with iDentification and qUantification sEparaTion (DUET). Commun Biol. 2020 08 03; 3(1):420. PMID: 32747637.
      Citations:    
    8. Eng CL, Lawson M, Zhu Q, Dries R, Koulena N, Takei Y, Yun J, Cronin C, Karp C, Yuan GC, Cai L. Transcriptome-scale super-resolved imaging in tissues by RNA seqFISH. Nature. 2019 04; 568(7751):235-239. PMID: 30911168.
      Citations:    
    9. Shah S, Takei Y, Zhou W, Lubeck E, Yun J, Eng CL, Koulena N, Cronin C, Karp C, Liaw EJ, Amin M, Cai L. Dynamics and Spatial Genomics of the Nascent Transcriptome by Intron seqFISH. Cell. 2018 07 12; 174(2):363-376.e16. PMID: 29887381.
      Citations:    
    10. Lignell A, Kerosuo L, Streichan SJ, Cai L, Bronner ME. Identification of a neural crest stem cell niche by Spatial Genomic Analysis. Nat Commun. 2017 11 28; 8(1):1830. PMID: 29184067.
      Citations:    
    11. Shah S, Lubeck E, Zhou W, Cai L. seqFISH Accurately Detects Transcripts in Single Cells and Reveals Robust Spatial Organization in the Hippocampus. Neuron. 2017 May 17; 94(4):752-758.e1. PMID: 28521130.
      Citations:    
    12. Takei Y, Shah S, Harvey S, Qi LS, Cai L. Multiplexed Dynamic Imaging of Genomic Loci by Combined CRISPR Imaging and DNA Sequential FISH. Biophys J. 2017 May 09; 112(9):1773-1776. PMID: 28427715.
      Citations:    
    13. Shah S, Lubeck E, Zhou W, Cai L. In Situ Transcription Profiling of Single Cells Reveals Spatial Organization of Cells in the Mouse Hippocampus. Neuron. 2016 Oct 19; 92(2):342-357. PMID: 27764670.
      Citations:    
    14. Shah S, Lubeck E, Schwarzkopf M, He TF, Greenbaum A, Sohn CH, Lignell A, Choi HM, Gradinaru V, Pierce NA, Cai L. Single-molecule RNA detection at depth by hybridization chain reaction and tissue hydrogel embedding and clearing. Development. 2016 08 01; 143(15):2862-7. PMID: 27342713.
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    15. Cai L. Turning single cells into microarrays by super-resolution barcoding. Brief Funct Genomics. 2013 Mar; 12(2):75-80. PMID: 23178478.
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