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Major histocompatibility complex class II inhibits fas antigen-mediated gastric mucosal cell apoptosis through actin-dependent inhibition of receptor aggregation.
Robotic system for MRI-guided stereotactic neurosurgery.
Moving mammogram-reluctant women to screening: a pilot study.
Changing nuclear landscape and unique PML structures during early epigenetic transitions of human embryonic stem cells.
Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease.
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Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease.
Mittal S, Cai Y, Nalam MN, Bolon DN, Schiffer CA. Hydrophobic core flexibility modulates enzyme activity in HIV-1 protease. J Am Chem Soc. 2012 Mar 07; 134(9):4163-8.
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PubMed
subject areas
Crystallography, X-Ray
Enzyme Activation
HIV Protease
Hydrophobic and Hydrophilic Interactions
Models, Molecular
Molecular Dynamics Simulation
Mutation
Protein Conformation
authors with profiles
Celia A Schiffer PhD
Daniel N Bolon PhD