Hydrophobic and Hydrophilic Interactions

"Hydrophobic and Hydrophilic Interactions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The thermodynamic interaction between a substance and WATER.

Descriptor ID	D057927
MeSH Number(s)	G02.409
Concept/Terms	Hydrophobic and Hydrophilic Interactions Hydrophobic and Hydrophilic Interactions Hydrophilic and Hydrophobic Interactions Hydrophobicity Hydrophobicity Hydrophobicities Hydrophobic Interactions Hydrophobic Interactions Hydrophobic Interaction Interaction, Hydrophobic Interactions, Hydrophobic Hydrophilic Interactions Hydrophilic Interactions Hydrophilic Interaction Interaction, Hydrophilic Interactions, Hydrophilic Hydrophilicity Hydrophilicity Hydrophilicities

Below are MeSH descriptors whose meaning is more general than "Hydrophobic and Hydrophilic Interactions".

Biological Sciences [G]
Chemical Phenomena [G02]
Hydrophobic and Hydrophilic Interactions [G02.409]

Below are MeSH descriptors whose meaning is more specific than "Hydrophobic and Hydrophilic Interactions".

Hydrophobic and Hydrophilic Interactions
Wettability

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hydrophobic and Hydrophilic Interactions" by people in this website by year, and whether "Hydrophobic and Hydrophilic Interactions" was a major or minor topic of these publications.

Bar chart showing 229 publications over 25 distinct years, with a maximum of 19 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	3	3
2003	0	4	4
2004	0	3	3
2005	0	6	6
2006	0	4	4
2007	0	9	9
2008	0	4	4
2009	2	5	7
2010	0	4	4
2011	0	9	9
2012	0	16	16
2013	1	11	12
2014	2	9	11
2015	1	10	11
2016	1	10	11
2017	0	15	15
2018	0	11	11
2019	0	19	19
2020	1	14	15
2021	0	12	12
2022	0	6	6
2023	1	2	3
2024	5	6	11
2025	0	15	15
2026	1	7	8

Below are the most recent publications written about "Hydrophobic and Hydrophilic Interactions" by people in Profiles.

Li Z, Zeng X, Dai T, McClements DJ, Lu Y, Shuai X, Deng L, Dong H, Chen J. One-step method for modification of soy protein isolate and preparation of stable protein emulsions by industrial-scale high-energy fluidic microfluidizer. Food Chem. 2026 Aug 15; 520:149833.

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Kang D, Yang Y, McClements DJ, Chen J, Ma D. Lotus leaf-inspired silk fibroin/sericin biomimetic active packaging films: Preparation, characterization, and application in extending shelf-life of pork and shrimp. Int J Biol Macromol. 2026 Jun; 367:152644.

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Richardson JD, Rotello VM, Van Lehn RC. Mechanistic insights into hydrophobicity-dependent antimicrobial selectivity of quaternary ammonium poly(oxanorborneneimide) polymers using coarse-grained simulations. Soft Matter. 2026 May 20; 22(19):3488-3505.

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Wang Z, Kou X, Wang S, Han Y, Xu D, McClements DJ, Chen X, Chen S. Interaction and formation mechanism of zein-yeast carboxymethyl glucan nanoparticles for the encapsulation of curcumin. Int J Biol Macromol. 2026 May; 362:152055.

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Shuai X, Fang M, McClements DJ, Chen T, Wang Z, Du L, Zhang M, Zhou W, Dai T, Li J, Chen J. Enhancement of macadamia protein solubility and functionality using combined pH-shift-heat treatment: Role of ionic environment (PBS vs water). Food Chem. 2026 May 30; 512:148937.

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Zhang X, Ma X, Wu C, Zheng Y, Hu H, McClements DJ, Wang Q, Shi A. Effect of heat or enzymatic cross-linking treatments on the interfacial and foaming properties of soy, mung bean, and yeast proteins. Int J Biol Macromol. 2026 Apr; 354:151311.

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Fakih HH, Zain Ui Abideen M, Rachid MO, Gross KY, Ormsby TJR, Ross VM, Gagnon R, Dahlke C, Furgal RC, Lochmann C, Summers A, Sleiman HF, F?rst SM, Jackson SN, Gordilho JO, Bouix-Peter C, Portal T, Tang Q, Harris JE, Khvorova A, Blanchard C, Alterman JF. Intradermal delivery of lipophilic siRNAs enables prolonged skin retention and sustained gene silencing in a porcine model. Nat Commun. 2026 Feb 03; 17(1).

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Raza M, Haspel N, Sharma A, Choi SH, De Luna X, Evans JJ. Evaluation of CendR peptides mined from protein databases as potential inhibitors of neuropilin-1 using an in-silico molecular modeling approach. J Mol Graph Model. 2026 May; 144:109279.

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Huang A, McClements DJ, Hu X, Luo S, Liu C, Ye J. Fabrication of food-grade lipid nanodisc-based delivery systems: Structural characterization and self-assembly process. Food Chem. 2026 Feb 15; 502:147730.

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Li Y, Chen X, Hu X, Qin D, Zhang S, Liu J, Zhang T, Du Z, McClements DJ. Comparative effects of heat-induced fibrillation and pH-shifting on the structure and interfacial adsorption of soy protein. Food Res Int. 2026 Jan 31; 224:117959.

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