Hydrophobic and Hydrophilic Interactions

"Hydrophobic and Hydrophilic Interactions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The thermodynamic interaction between a substance and WATER.

Descriptor ID	D057927
MeSH Number(s)	G02.409
Concept/Terms	Hydrophobic and Hydrophilic Interactions Hydrophobic and Hydrophilic Interactions Hydrophilic and Hydrophobic Interactions Hydrophobicity Hydrophobicity Hydrophobicities Hydrophobic Interactions Hydrophobic Interactions Hydrophobic Interaction Interaction, Hydrophobic Interactions, Hydrophobic Hydrophilic Interactions Hydrophilic Interactions Hydrophilic Interaction Interaction, Hydrophilic Interactions, Hydrophilic Hydrophilicity Hydrophilicity Hydrophilicities

Below are MeSH descriptors whose meaning is more general than "Hydrophobic and Hydrophilic Interactions".

Biological Sciences [G]
Chemical Phenomena [G02]
Hydrophobic and Hydrophilic Interactions [G02.409]

Below are MeSH descriptors whose meaning is more specific than "Hydrophobic and Hydrophilic Interactions".

Hydrophobic and Hydrophilic Interactions
Wettability

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hydrophobic and Hydrophilic Interactions" by people in this website by year, and whether "Hydrophobic and Hydrophilic Interactions" was a major or minor topic of these publications.

Bar chart showing 212 publications over 24 distinct years, with a maximum of 19 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	3	3
2003	0	3	3
2004	0	3	3
2005	0	6	6
2006	0	4	4
2007	0	9	9
2008	0	4	4
2009	2	5	7
2010	0	4	4
2011	0	9	9
2012	0	16	16
2013	1	10	11
2014	2	9	11
2015	1	10	11
2016	1	10	11
2017	0	15	15
2018	0	11	11
2019	0	19	19
2020	1	14	15
2021	0	12	12
2022	0	6	6
2023	1	2	3
2024	5	6	11
2025	0	8	8

Below are the most recent publications written about "Hydrophobic and Hydrophilic Interactions" by people in Profiles.

Geng Q, McClements DJ, Dai T, Zhou W, Wu Z, Chen H. Exploration of Non-Covalent Interactions of Peanut Allergen Ara h 2 With Tannic Acid: Insights Into Molecular Structure and In Vitro Allergenicity. J Food Sci. 2025 Aug; 90(8):e70432.

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Cheng H, McClements DJ, Xu H, Zhang Z, Zhang R, Jin Z, Chen L. Effect of various natural cross-linking agents on the properties of corn starch/soy protein isolate composite films. Carbohydr Polym. 2025 Oct 15; 366:123850.

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Chang SY, McAnena AP, Kim J, Song J. Tuning Hyaluronic Acid Microstructures by Engineered Amphiphilicity: From Dynamically Cross-Linked Gels to Multilayered Nanoparticles. ACS Appl Mater Interfaces. 2025 Jun 04; 17(22):31909-31922.

View in: PubMed
Wang J, Sun S, Rashid A, McClements DJ, Ding X, Hou H, Kong L, Sun C, Wang W. Impact of fatty acid chain length and content on hydrophobicity of starch films: Structure-property analysis. Int J Biol Macromol. 2025 Jun; 315(Pt 2):144563.

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Chiang MC, Clarke BR, Tew GN, Schiffman JD. Antifouling Activity of Bottlebrush Network Hydrogels. ACS Appl Bio Mater. 2025 May 19; 8(5):4200-4208.

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Gu Q, Lu G, Han J, McClements DJ, Ma C, Liu X, Liu F. Design, fabrication, and performance evaluation of curcumin-loaded nanoparticles based on zein, hyaluronic acid, and tannic acid. Int J Biol Macromol. 2025 May; 309(Pt 3):142884.

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Sun S, Ji Y, McClements DJ, Song H, Liu R, Gao S, Sun C, Hou H, Wang W. Tailoring the hydrophobic structure of starch films: Selective distribution of beeswax via ultrasonication and homogenization. Int J Biol Macromol. 2025 May; 307(Pt 4):142288.

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Liu H, Liu Y, Peng S, Zhou L, McClements DJ, Fang S, Liu W. Colonic delivery and controlled release of curcumin encapsulated within plant-based extracellular vesicles loaded into hydrogel beads. Food Res Int. 2025 Feb; 202:115540.

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Huang R, Hirschbiegel CM, Luther DC, Li CH, Nabawy A, Park J, Ribbe A, Xu Y, Rotello VM. Controlled bioorthogonal catalyst self-assembly and activity using rationally designed polymer scaffolds. Nanoscale. 2024 Dec 19; 17(1):390-397.

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Nabawy A, Chattopadhyay AN, Makabenta JMV, Hassan MA, Yang J, Park J, Jiang M, Jeon T, Im J, Rotello VM. Cationic conjugated polymers with tunable hydrophobicity for efficient treatment of multidrug-resistant wound biofilm infections. Biomaterials. 2025 May; 316:123015.

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