Peptidoglycan

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"Peptidoglycan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A structural polymer of the bacterial cell envelope consisting of sugars and amino acids which is responsible for both shape determination and cellular integrity under osmotic stress in virtually all bacteria.

Descriptor ID	D010457
MeSH Number(s)	D09.400.420.700 D09.698.718.594 D12.644.233.594 D12.776.395.560.800 D23.050.161.616.594
Concept/Terms	Peptidoglycan Peptidoglycan Murein Pseudomurein Pseudomurein

Below are MeSH descriptors whose meaning is more general than "Peptidoglycan".

Chemicals and Drugs [D]
Carbohydrates [D09]
Glycoconjugates [D09.400]
Glycopeptides [D09.400.420]
Peptidoglycan [D09.400.420.700]
Polysaccharides [D09.698]
Polysaccharides, Bacterial [D09.698.718]
Peptidoglycan [D09.698.718.594]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Glycopeptides [D12.644.233]
Peptidoglycan [D12.644.233.594]
Proteins [D12.776]
Glycoproteins [D12.776.395]
Mucoproteins [D12.776.395.560]
Peptidoglycan [D12.776.395.560.800]
Biological Factors [D23]
Antigens [D23.050]
Antigens, Bacterial [D23.050.161]
Polysaccharides, Bacterial [D23.050.161.616]
Peptidoglycan [D23.050.161.616.594]

Below are MeSH descriptors whose meaning is related to "Peptidoglycan".

Below are MeSH descriptors whose meaning is more specific than "Peptidoglycan".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Peptidoglycan" by people in this website by year, and whether "Peptidoglycan" was a major or minor topic of these publications.

Bar chart showing 35 publications over 18 distinct years, with a maximum of 5 publications in 2006 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	0	1	1
2004	1	0	1
2005	1	2	3
2006	3	2	5
2007	1	0	1
2008	1	1	2
2009	1	2	3
2012	0	1	1
2013	0	1	1
2015	2	0	2
2016	2	0	2
2017	1	0	1
2018	2	3	5
2019	1	1	2
2021	1	1	2
2022	1	0	1
2023	0	1	1

Below are the most recent publications written about "Peptidoglycan" by people in Profiles.

Bharadwaj R, Lusi CF, Mashayekh S, Nagar A, Subbarao M, Kane GI, Wodzanowski KA, Brown AR, Okuda K, Monahan A, Paik D, Nandy A, Anonick MV, Goldman WE, Kanneganti TD, Orzalli MH, Grimes CL, Atukorale PU, Silverman N. Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity. Immunity. 2023 05 09; 56(5):998-1012.e8.

View in: PubMed
Melzer ES, Kado T, Garc?a-Heredia A, Gupta KR, Meniche X, Morita YS, Sassetti CM, Rego EH, Siegrist MS. Cell Wall Damage Reveals Spatial Flexibility in Peptidoglycan Synthesis and a Nonredundant Role for RodA in Mycobacteria. J Bacteriol. 2022 06 21; 204(6):e0054021.

View in: PubMed
Brown AR, Wodzanowski KA, Santiago CC, Hyland SN, Follmar JL, Asare-Okai P, Grimes CL. Protected N-Acetyl Muramic Acid Probes Improve Bacterial Peptidoglycan Incorporation via Metabolic Labeling. ACS Chem Biol. 2021 10 15; 16(10):1908-1916.

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Garc?a-Heredia A, Kado T, Sein CE, Puffal J, Osman SH, Judd J, Gray TA, Morita YS, Siegrist MS. Membrane-partitioned cell wall synthesis in mycobacteria. Elife. 2021 02 05; 10.

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Shamma F, Papavinasasundaram K, Quintanilla SY, Bandekar A, Sassetti C, Boutte CC. Phosphorylation on PstP Regulates Cell Wall Metabolism and Antibiotic Tolerance in Mycobacterium smegmatis. J Bacteriol. 2021 01 25; 203(4).

View in: PubMed
Brown AR, Gordon RA, Hyland SN, Siegrist MS, Grimes CL. Chemical Biology Tools for Examining the Bacterial Cell Wall. Cell Chem Biol. 2020 08 20; 27(8):1052-1062.

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Ukaegbu OI, DeMeester KE, Liang H, Brown AR, Jones ZS, Grimes CL. Utility of bacterial peptidoglycan recycling enzymes in the chemoenzymatic synthesis of valuable UDP sugar substrates. Methods Enzymol. 2020; 638:1-26.

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Lariviere PJ, Mahone CR, Santiago-Collazo G, Howell M, Daitch AK, Zeinert R, Chien P, Brown PJB, Goley ED. An Essential Regulator of Bacterial Division Links FtsZ to Cell Wall Synthase Activation. Curr Biol. 2019 05 06; 29(9):1460-1470.e4.

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D'Ambrosio EA, Drake WR, Mashayekh S, Ukaegbu OI, Brown AR, Grimes CL. Modulation of the NOD-like receptors NOD1 and NOD2: A chemist's perspective. Bioorg Med Chem Lett. 2019 05 15; 29(10):1153-1161.

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Rahlwes KC, Sparks IL, Morita YS. Cell Walls and Membranes of Actinobacteria. Subcell Biochem. 2019; 92:417-469.

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