Apoptosis

"Apoptosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

One of the mechanisms by which CELL DEATH occurs (compare with NECROSIS and AUTOPHAGOCYTOSIS). Apoptosis is the mechanism responsible for the physiological deletion of cells and appears to be intrinsically programmed. It is characterized by distinctive morphologic changes in the nucleus and cytoplasm, chromatin cleavage at regularly spaced sites, and the endonucleolytic cleavage of genomic DNA; (DNA FRAGMENTATION); at internucleosomal sites. This mode of cell death serves as a balance to mitosis in regulating the size of animal tissues and in mediating pathologic processes associated with tumor growth.

Descriptor ID	D017209
MeSH Number(s)	G04.146.160
Concept/Terms	Apoptosis Apoptosis Programmed Cell Death, Type I Apoptosis, Intrinsic Pathway Apoptosis, Intrinsic Pathway Apoptoses, Intrinsic Pathway Intrinsic Pathway Apoptoses Intrinsic Pathway Apoptosis Apoptosis, Extrinsic Pathway Apoptosis, Extrinsic Pathway Apoptoses, Extrinsic Pathway Extrinsic Pathway Apoptoses Extrinsic Pathway Apoptosis

Below are MeSH descriptors whose meaning is more general than "Apoptosis".

Biological Sciences [G]
Cell Physiological Phenomena [G04]
Cell Death [G04.146]
Apoptosis [G04.146.160]

Below are MeSH descriptors whose meaning is related to "Apoptosis".

Below are MeSH descriptors whose meaning is more specific than "Apoptosis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Apoptosis" by people in this website by year, and whether "Apoptosis" was a major or minor topic of these publications.

Bar chart showing 840 publications over 31 distinct years, with a maximum of 53 publications in 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1993	4	1	5
1994	6	1	7
1995	15	0	15
1996	11	7	18
1997	6	3	9
1998	11	5	16
1999	15	8	23
2000	12	6	18
2001	6	4	10
2002	15	13	28
2003	28	23	51
2004	14	26	40
2005	17	25	42
2006	24	29	53
2007	12	16	28
2008	17	23	40
2009	17	22	39
2010	15	25	40
2011	13	29	42
2012	12	23	35
2013	10	27	37
2014	22	20	42
2015	6	24	30
2016	11	24	35
2017	10	22	32
2018	12	23	35
2019	7	20	27
2020	5	6	11
2021	7	12	19
2022	0	7	7
2023	2	4	6

Below are the most recent publications written about "Apoptosis" by people in Profiles.

Lentini G, Fam? A, De Gaetano GV, Coppolino F, Mahjoub AK, Ryan L, Lien E, Espevik T, Beninati C, Teti G. Caspase-8 inhibition improves the outcome of bacterial infections in mice by promoting neutrophil activation. Cell Rep Med. 2023 07 18; 4(7):101098.

View in: PubMed
Suthar KP, Bergmann A. Something new under the sun: caspases promote cell survival under moderate heat stress. EMBO Rep. 2023 06 05; 24(6):e57276.

View in: PubMed
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, Balachandran S, Bano D, Barlev NA, Bartek J, Bazan NG, Becker C, Bernassola F, Bertrand MJM, Bianchi ME, Blagosklonny MV, Blander JM, Blandino G, Blomgren K, Borner C, Bortner CD, Bove P, Boya P, Brenner C, Broz P, Brunner T, Damgaard RB, Calin GA, Campanella M, Candi E, Carbone M, Carmona-Gutierrez D, Cecconi F, Chan FK, Chen GQ, Chen Q, Chen YH, Cheng EH, Chipuk JE, Cidlowski JA, Ciechanover A, Ciliberto G, Conrad M, Cubillos-Ruiz JR, Czabotar PE, D'Angiolella V, Daugaard M, Dawson TM, Dawson VL, De Maria R, De Strooper B, Debatin KM, Deberardinis RJ, Degterev A, Del Sal G, Deshmukh M, Di Virgilio F, Diederich M, Dixon SJ, Dynlacht BD, El-Deiry WS, Elrod JW, Engeland K, Fimia GM, Galassi C, Ganini C, Garcia-Saez AJ, Garg AD, Garrido C, Gavathiotis E, Gerlic M, Ghosh S, Green DR, Greene LA, Gronemeyer H, H?cker G, Hajn?czky G, Hardwick JM, Haupt Y, He S, Heery DM, Hengartner MO, Hetz C, Hildeman DA, Ichijo H, Inoue S, J??ttel? M, Janic A, Joseph B, Jost PJ, Kanneganti TD, Karin M, Kashkar H, Kaufmann T, Kelly GL, Kepp O, Kimchi A, Kitsis RN, Klionsky DJ, Kluck R, Krysko DV, Kulms D, Kumar S, Lavandero S, Lavrik IN, Lemasters JJ, Liccardi G, Linkermann A, Lipton SA, Lockshin RA, L?pez-Ot?n C, Luedde T, MacFarlane M, Madeo F, Malorni W, Manic G, Mantovani R, Marchi S, Marine JC, Martin SJ, Martinou JC, Mastroberardino PG, Medema JP, Mehlen P, Meier P, Melino G, Melino S, Miao EA, Moll UM, Mu?oz-Pinedo C, Murphy DJ, Niklison-Chirou MV, Novelli F, N??ez G, Oberst A, Ofengeim D, Opferman JT, Oren M, Pagano M, Panaretakis T, Pasparakis M, Penninger JM, Pentimalli F, Pereira DM, Pervaiz S, Peter ME, Pinton P, Porta G, Prehn JHM, Puthalakath H, Rabinovich GA, Rajalingam K, Ravichandran KS, Rehm M, Ricci JE, Rizzuto R, Robinson N, Rodrigues CMP, Rotblat B, Rothlin CV, Rubinsztein DC, Rudel T, Rufini A, Ryan KM, Sarosiek KA, Sawa A, Sayan E, Schroder K, Scorrano L, Sesti F, Shao F, Shi Y, Sica GS, Silke J, Simon HU, Sistigu A, Stephanou A, Stockwell BR, Strapazzon F, Strasser A, Sun L, Sun E, Sun Q, Szabadkai G, Tait SWG, Tang D, Tavernarakis N, Troy CM, Turk B, Urbano N, Vandenabeele P, Vanden Berghe T, Vander Heiden MG, Vanderluit JL, Verkhratsky A, Villunger A, von Karstedt S, Voss AK, Vousden KH, Vucic D, Vuri D, Wagner EF, Walczak H, Wallach D, Wang R, Wang Y, Weber A, Wood W, Yamazaki T, Yang HT, Zakeri Z, Zawacka-Pankau JE, Zhang L, Zhang H, Zhivotovsky B, Zhou W, Piacentini M, Kroemer G, Galluzzi L. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death Differ. 2023 05; 30(5):1097-1154.

View in: PubMed
Zheng D, Mohapatra G, Kern L, He Y, Shmueli MD, Vald?s-Mas R, Kolodziejczyk AA, Pr?chnicki T, Vasconcelos MB, Schorr L, Hertel F, Lee YS, Rufino MC, Ceddaha E, Shimshy S, Hodgetts RJ, Dori-Bachash M, Kleimeyer C, Goldenberg K, Heinemann M, Stettner N, Harmelin A, Shapiro H, Puschhof J, Chen M, Flavell RA, Latz E, Merbl Y, Abdeen SK, Elinav E. Epithelial Nlrp10 inflammasome mediates protection against intestinal autoinflammation. Nat Immunol. 2023 04; 24(4):585-594.

View in: PubMed
Li X, He Y, Zhang S, Gu Q, McClements DJ, Chen S, Liu X, Liu F. Lactoferrin-Based Ternary Composite Nanoparticles with Enhanced Dispersibility and Stability for Curcumin Delivery. ACS Appl Mater Interfaces. 2023 Apr 12; 15(14):18166-18181.

View in: PubMed
Lei X, Chen Y, Lien E, Fitzgerald KA. MLKL-Driven Inflammasome Activation and Caspase-8 Mediate Inflammatory Cell Death in Influenza A Virus Infection. mBio. 2023 04 25; 14(2):e0011023.

View in: PubMed
Farrell L, Puig-Barbe A, Haque MI, Amcheslavsky A, Yu M, Bergmann A, Fan Y. Actin remodeling mediates ROS production and JNK activation to drive apoptosis-induced proliferation. PLoS Genet. 2022 12; 18(12):e1010533.

View in: PubMed
Yarikipati P, Bergmann A. In Vitro Cleavage Assays using Purified Recombinant Drosophila Caspases for Substrate Screening. J Vis Exp. 2022 10 06; (188).

View in: PubMed
Gardner HL, Fenger JM, Roberts RD, London CA. Characterizing the metabolic role of STAT3 in canine osteosarcoma. Vet Comp Oncol. 2022 Dec; 20(4):817-824.

View in: PubMed
Ly L, Cheng X, Murthy SRK, Jones OZ, Zhuang T, Gitelis S, Blank AT, Nissan A, Adileh M, Colman M, Keidar M, Basadonna G, Canady J. Canady Cold Helios Plasma Reduces Soft Tissue Sarcoma Viability by Inhibiting Proliferation, Disrupting Cell Cycle, and Inducing Apoptosis: A Preliminary Report. Molecules. 2022 Jun 29; 27(13).

View in: PubMed

People

Explore

Similar Concepts

Top Journals