Early Growth Response Protein 2
"Early Growth Response Protein 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An early growth response transcription factor that controls the formation of the MYELIN SHEATH around peripheral AXONS by SCHWANN CELLS. Mutations in EGR2 transcription factor have been associated with HEREDITARY MOTOR AND SENSORY NEUROPATHIES such as CHARCOT-MARIE-TOOTH DISEASE.
| Descriptor ID |
D051767
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| MeSH Number(s) |
D12.776.260.158.750 D12.776.460.525.750 D12.776.930.213.750
|
| Concept/Terms |
Early Growth Response Protein 2- Early Growth Response Protein 2
- Krox-20 Transcription Factor
- Krox 20 Transcription Factor
- Transcription Factor, Krox-20
- EGR2 Transcription Factor
- Transcription Factor, EGR2
- Krox20 Protein
|
Below are MeSH descriptors whose meaning is more general than "Early Growth Response Protein 2".
Below are MeSH descriptors whose meaning is more specific than "Early Growth Response Protein 2".
This graph shows the total number of publications written about "Early Growth Response Protein 2" by people in this website by year, and whether "Early Growth Response Protein 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Early Growth Response Protein 2" by people in Profiles.
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Gregory KJ, Morin SM, Schneider SS. Regulation of early growth response 2 expression by secreted frizzled related protein 1. BMC Cancer. 2017 Jul 07; 17(1):473.
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Liu H, Zhu S, Zhang C, Lu P, Hu J, Yin Z, Ma Y, Chen X, OuYang H. Crucial transcription factors in tendon development and differentiation: their potential for tendon regeneration. Cell Tissue Res. 2014 May; 356(2):287-98.
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Ram?n HE, Cejas PJ, LaRosa D, Rahman A, Harris JE, Zhang J, Hunter C, Choi Y, Turka LA. EGR-2 is not required for in vivo CD4 T cell mediated immune responses. PLoS One. 2010 Sep 23; 5(9):e12904.
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Yu L, Haverty PM, Mariani J, Wang Y, Shen HY, Schwarzschild MA, Weng Z, Chen JF. Genetic and pharmacological inactivation of adenosine A2A receptor reveals an Egr-2-mediated transcriptional regulatory network in the mouse striatum. Physiol Genomics. 2005 Sep 21; 23(1):89-102.
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Harris JE, Bishop KD, Phillips NE, Mordes JP, Greiner DL, Rossini AA, Czech MP. Early growth response gene-2, a zinc-finger transcription factor, is required for full induction of clonal anergy in CD4+ T cells. J Immunol. 2004 Dec 15; 173(12):7331-8.