"Guanfacine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A centrally acting antihypertensive agent with specificity towards ADRENERGIC ALPHA-2 RECEPTORS.
| Descriptor ID |
D016316
|
| MeSH Number(s) |
D02.078.370.465 D02.241.223.601.329
|
| Concept/Terms |
Guanfacine Hydrochloride- Guanfacine Hydrochloride
- Hydrochloride, Guanfacine
- Guanfacine Monohydrochloride
- Monohydrochloride, Guanfacine
|
Below are MeSH descriptors whose meaning is more general than "Guanfacine".
Below are MeSH descriptors whose meaning is more specific than "Guanfacine".
This graph shows the total number of publications written about "Guanfacine" by people in this website by year, and whether "Guanfacine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 1 | 1 | 2 |
| 2018 | 0 | 2 | 2 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Guanfacine" by people in Profiles.
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Brown JA, Petersen N, Centanni SW, Jin AY, Yoon HJ, Cajigas SA, Bedenbaugh MN, Luchsinger JR, Patel S, Calipari ES, Simerly RB, Winder DG. An ensemble recruited by a2a-adrenergic receptors is engaged in a stressor-specific manner in mice. Neuropsychopharmacology. 2023 07; 48(8):1133-1143.
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Perez RE, Basu A, Nabit BP, Harris NA, Folkes OM, Patel S, Gilsbach R, Hein L, Winder DG. a2A-adrenergic heteroreceptors are required for stress-induced reinstatement of cocaine conditioned place preference. Neuropsychopharmacology. 2020 08; 45(9):1473-1481.
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Fetterly TL, Basu A, Nabit BP, Awad E, Williford KM, Centanni SW, Matthews RT, Silberman Y, Winder DG. a2A-Adrenergic Receptor Activation Decreases Parabrachial Nucleus Excitatory Drive onto BNST CRF Neurons and Reduces Their Activity In Vivo. J Neurosci. 2019 01 16; 39(3):472-484.
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Harris NA, Isaac AT, G?nther A, Merkel K, Melchior J, Xu M, Eguakun E, Perez R, Nabit BP, Flavin S, Gilsbach R, Shonesy B, Hein L, Abel T, Baumann A, Matthews R, Centanni SW, Winder DG. Dorsal BNST a2A-Adrenergic Receptors Produce HCN-Dependent Excitatory Actions That Initiate Anxiogenic Behaviors. J Neurosci. 2018 10 17; 38(42):8922-8942.
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Shields AD, Wang Q, Winder DG. alpha2A-adrenergic receptors heterosynaptically regulate glutamatergic transmission in the bed nucleus of the stria terminalis. Neuroscience. 2009 Sep 29; 163(1):339-51.
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Lu R, Li Y, Zhang Y, Chen Y, Shields AD, Winder DG, Angelotti T, Jiao K, Limbird LE, Zhou Y, Wang Q. Epitope-tagged receptor knock-in mice reveal that differential desensitization of alpha2-adrenergic responses is because of ligand-selective internalization. J Biol Chem. 2009 May 08; 284(19):13233-43.