"Granulosa Cell Tumor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neoplasm composed entirely of GRANULOSA CELLS, occurring mostly in the OVARY. In the adult form, it may contain some THECA CELLS. This tumor often produces ESTRADIOL and INHIBIN. The excess estrogen exposure can lead to other malignancies in women and PRECOCIOUS PUBERTY in girls. In rare cases, granulosa cell tumors have been identified in the TESTES.
| Descriptor ID |
D006106
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| MeSH Number(s) |
C04.557.475.750.656 C04.588.322.455.398 C13.351.500.056.630.705.398 C13.351.937.418.685.398 C19.344.410.398 C19.391.630.705.398
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| Concept/Terms |
Granulosa Cell Tumor- Granulosa Cell Tumor
- Granulosa Cell Tumors
- Tumor, Granulosa Cell
- Tumors, Granulosa Cell
Granulosa Cell Cancer- Granulosa Cell Cancer
- Cancer, Granulosa Cell
- Cancers, Granulosa Cell
- Cell Cancer, Granulosa
- Cell Cancers, Granulosa
- Granulosa Cell Cancers
- Cancer of Granulosa Cells
- Cells Cancer, Granulosa
- Cells Cancers, Granulosa
- Granulosa Cells Cancer
- Granulosa Cells Cancers
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Below are MeSH descriptors whose meaning is more general than "Granulosa Cell Tumor".
Below are MeSH descriptors whose meaning is more specific than "Granulosa Cell Tumor".
This graph shows the total number of publications written about "Granulosa Cell Tumor" by people in this website by year, and whether "Granulosa Cell Tumor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Granulosa Cell Tumor" by people in Profiles.
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Siegmund S, Sholl LM, Cornejo KM, Sangoi AR, Otis CN, Mehra R, Hirsch MS, Acosta AM. Molecular assessment of testicular adult granulosa cell tumor demonstrates significant differences when compared to ovarian counterparts. Mod Pathol. 2022 05; 35(5):697-704.
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Kao CS, Cornejo KM, Ulbright TM, Young RH. Juvenile granulosa cell tumors of the testis: a clinicopathologic study of 70 cases with emphasis on its wide morphologic spectrum. Am J Surg Pathol. 2015 Sep; 39(9):1159-69.
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Cornejo KM, Young RH. Adult granulosa cell tumors of the testis: a report of 32 cases. Am J Surg Pathol. 2014 Sep; 38(9):1242-50.
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Schacht V, Dadras SS, Johnson LA, Jackson DG, Hong YK, Detmar M. Up-regulation of the lymphatic marker podoplanin, a mucin-type transmembrane glycoprotein, in human squamous cell carcinomas and germ cell tumors. Am J Pathol. 2005 Mar; 166(3):913-21.
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Patterson MM, Rogers AB, Schrenzel MD, Marini RP, Fox JG. Alopecia attributed to neoplastic ovarian tissue in two ferrets. Comp Med. 2003 Apr; 53(2):213-7.
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Boggess JF, Soules MR, Goff BA, Greer BE, Cain JM, Tamimi HK. Serum inhibin and disease status in women with ovarian granulosa cell tumors. Gynecol Oncol. 1997 Jan; 64(1):64-9.
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Beamer WG, Shultz KL, Tennent BJ, Shultz LD. Granulosa cell tumorigenesis in genetically hypogonadal-immunodeficient mice grafted with ovaries from tumor-susceptible donors. Cancer Res. 1993 Aug 15; 53(16):3741-6.
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Gustafson ML, Lee MM, Asmundson L, MacLaughlin DT, Donahoe PK. M?llerian inhibiting substance in the diagnosis and management of intersex and gonadal abnormalities. J Pediatr Surg. 1993 Mar; 28(3):439-44.
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Tennent BJ, Beamer WG, Shultz LD, Adamson ED. Epidermal growth factor receptors in spontaneous ovarian granulosa cell tumors of SWR-derived mice. Int J Cancer. 1989 Sep 15; 44(3):477-82.
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Beamer WG, Tennent BJ, Shultz KL, Nadeau JH, Shultz LD, Skow LC. Gene for ovarian granulosa cell tumor susceptibility, Gct, in SWXJ recombinant inbred strains of mice revealed by dehydroepiandrosterone. Cancer Res. 1988 Sep 15; 48(18):5092-5.