"E-Box Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.
| Descriptor ID |
D024721
|
| MeSH Number(s) |
G02.111.570.080.689.330.240 G05.360.080.689.330.240 G05.360.340.024.340.137.750.249.240
|
| Concept/Terms |
E-Box Elements- E-Box Elements
- E Box Elements
- E-Box Element
- Element, E-Box
- Elements, E-Box
- E-Box Sequences
- E Box Sequences
- E-Box Sequence
- Sequence, E-Box
- Sequences, E-Box
- E-Box Sites
- E Box Sites
- E-Box Site
- Site, E-Box
- Sites, E-Box
- E-Box Motifs
- E Box Motifs
- E-Box Motif
- Motif, E-Box
- Motifs, E-Box
|
Below are MeSH descriptors whose meaning is more general than "E-Box Elements".
Below are MeSH descriptors whose meaning is more specific than "E-Box Elements".
This graph shows the total number of publications written about "E-Box Elements" by people in this website by year, and whether "E-Box Elements" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
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click here.
Below are the most recent publications written about "E-Box Elements" by people in Profiles.
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Zhang Y, Lian JB, Stein JL, van Wijnen AJ, Stein GS. The Notch-responsive transcription factor Hes-1 attenuates osteocalcin promoter activity in osteoblastic cells. J Cell Biochem. 2009 Oct 15; 108(3):651-9.
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Sun Y, Ishibashi M, Seimon T, Lee M, Sharma SM, Fitzgerald KA, Samokhin AO, Wang Y, Sayers S, Aikawa M, Jerome WG, Ostrowski MC, Bromme D, Libby P, Tabas IA, Welch CL, Tall AR. Free cholesterol accumulation in macrophage membranes activates Toll-like receptors and p38 mitogen-activated protein kinase and induces cathepsin K. Circ Res. 2009 Feb 27; 104(4):455-65.
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Zhang Y, Hassan MQ, Li ZY, Stein JL, Lian JB, van Wijnen AJ, Stein GS. Intricate gene regulatory networks of helix-loop-helix (HLH) proteins support regulation of bone-tissue related genes during osteoblast differentiation. J Cell Biochem. 2008 Oct 01; 105(2):487-96.
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Slack A, Chen Z, Tonelli R, Pule M, Hunt L, Pession A, Shohet JM. The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma. Proc Natl Acad Sci U S A. 2005 Jan 18; 102(3):731-6.