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Pyrimidine Nucleotides
Tumor Cell-Free DNA Copy Number Instability Predicts Therapeutic Response to Immunotherapy.
Barriers to Healthcare Access and to Improvements in Health-Related Quality of Life After an Acute Coronary Syndrome (From TRACE-CORE).
Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver.
Allosteric inhibition of the NS2B-NS3 protease from dengue virus.
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Allosteric inhibition of the NS2B-NS3 protease from dengue virus.
Yildiz M, Ghosh S, Bell JA, Sherman W, Hardy JA. Allosteric inhibition of the NS2B-NS3 protease from dengue virus. ACS Chem Biol. 2013 Dec 20; 8(12):2744-52.
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subject areas
Allosteric Regulation
Allosteric Site
Antiviral Agents
Catalytic Domain
Cysteine
Dengue Virus
Enzyme Activation
Kinetics
Molecular Docking Simulation
Molecular Probes
Mutation
Protease Inhibitors
Protein Binding
Protein Structure, Secondary
Protein Structure, Tertiary
Serine Endopeptidases
Structure-Activity Relationship
Viral Nonstructural Proteins
authors with profiles
Jeanne A Hardy BS, PhD