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Orchestration of pulmonary T cell immunity during Mycobacterium tuberculosis infection: immunity interruptus.
Model systems for flavoenzyme activity. The effects of specific hydrogen bonds on the 13C and 1H NMR of flavins.
Pitch Perception
Multiple proteolytic events in caspase-6 self-activation impact conformations of discrete structural regions.
Allosteric inhibition of the NS2B-NS3 protease from dengue virus.
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Allosteric inhibition of the NS2B-NS3 protease from dengue virus.
Yildiz M, Ghosh S, Bell JA, Sherman W, Hardy JA. Allosteric inhibition of the NS2B-NS3 protease from dengue virus. ACS Chem Biol. 2013 Dec 20; 8(12):2744-52.
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subject areas
Allosteric Regulation
Allosteric Site
Antiviral Agents
Catalytic Domain
Cysteine
Dengue Virus
Enzyme Activation
Kinetics
Molecular Docking Simulation
Molecular Probes
Mutation
Protease Inhibitors
Protein Binding
Protein Structure, Secondary
Protein Structure, Tertiary
Serine Endopeptidases
Structure-Activity Relationship
Viral Nonstructural Proteins
authors with profiles
Jeanne A Hardy BS, PhD