CD8-Positive T-Lymphocytes

"CD8-Positive T-Lymphocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A critical subpopulation of regulatory T-lymphocytes involved in MHC Class I-restricted interactions. They include both cytotoxic T-lymphocytes (T-LYMPHOCYTES, CYTOTOXIC) and CD8+ suppressor T-lymphocytes.

Descriptor ID	D018414
MeSH Number(s)	A11.118.637.555.567.569.220 A15.145.229.637.555.567.569.220 A15.382.490.555.567.569.220
Concept/Terms	CD8-Positive T-Lymphocytes CD8-Positive T-Lymphocytes CD8 Positive T Lymphocytes CD8-Positive T-Lymphocyte T-Lymphocyte, CD8-Positive T-Lymphocytes, CD8-Positive T8 Lymphocytes Lymphocyte, T8 Lymphocytes, T8 T8 Lymphocyte T8 Cells Cell, T8 Cells, T8 T8 Cell CD8-Positive Lymphocytes CD8 Positive Lymphocytes CD8-Positive Lymphocyte Lymphocyte, CD8-Positive Lymphocytes, CD8-Positive Suppressor T-Lymphocytes, CD8-Positive Suppressor T-Lymphocytes, CD8-Positive CD8-Positive Suppressor T-Lymphocyte CD8-Positive Suppressor T-Lymphocytes Suppressor T Lymphocytes, CD8 Positive Suppressor T-Lymphocyte, CD8-Positive T-Lymphocyte, CD8-Positive Suppressor T-Lymphocytes, CD8-Positive Suppressor Suppressor T-Cells, CD8-Positive CD8-Positive Suppressor T-Cell CD8-Positive Suppressor T-Cells Suppressor T Cells, CD8 Positive Suppressor T-Cell, CD8-Positive T-Cell, CD8-Positive Suppressor T-Cells, CD8-Positive Suppressor

Below are MeSH descriptors whose meaning is more general than "CD8-Positive T-Lymphocytes".

Anatomy [A]
Cells [A11]
Blood Cells [A11.118]
Leukocytes [A11.118.637]
Leukocytes, Mononuclear [A11.118.637.555]
Lymphocytes [A11.118.637.555.567]
T-Lymphocytes [A11.118.637.555.567.569]
CD8-Positive T-Lymphocytes [A11.118.637.555.567.569.220]
Hemic and Immune Systems [A15]
Blood [A15.145]
Blood Cells [A15.145.229]
Leukocytes [A15.145.229.637]
Leukocytes, Mononuclear [A15.145.229.637.555]
Lymphocytes [A15.145.229.637.555.567]
T-Lymphocytes [A15.145.229.637.555.567.569]
CD8-Positive T-Lymphocytes [A15.145.229.637.555.567.569.220]
Immune System [A15.382]
Leukocytes [A15.382.490]
Leukocytes, Mononuclear [A15.382.490.555]
Lymphocytes [A15.382.490.555.567]
T-Lymphocytes [A15.382.490.555.567.569]
CD8-Positive T-Lymphocytes [A15.382.490.555.567.569.220]

Below are MeSH descriptors whose meaning is related to "CD8-Positive T-Lymphocytes".

Below are MeSH descriptors whose meaning is more specific than "CD8-Positive T-Lymphocytes".

CD8-Positive T-Lymphocytes
T-Lymphocytes, Cytotoxic

publications

Timeline | Most Recent

This graph shows the total number of publications written about "CD8-Positive T-Lymphocytes" by people in this website by year, and whether "CD8-Positive T-Lymphocytes" was a major or minor topic of these publications.

Bar chart showing 429 publications over 29 distinct years, with a maximum of 27 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	2	3	5
1995	2	2	4
1996	0	1	1
1997	1	1	2
1998	3	5	8
1999	5	1	6
2000	5	1	6
2001	4	8	12
2002	12	0	12
2003	10	8	18
2004	17	6	23
2005	15	6	21
2006	17	9	26
2007	13	13	26
2008	20	7	27
2009	12	10	22
2010	18	5	23
2011	8	8	16
2012	14	10	24
2013	8	4	12
2014	13	6	19
2015	14	5	19
2016	11	5	16
2017	11	2	13
2018	9	5	14
2019	12	9	21
2020	9	7	16
2021	4	9	13
2022	0	4	4

Below are the most recent publications written about "CD8-Positive T-Lymphocytes" by people in Profiles.

Lefler JE, MarElia-Bennett CB, Thies KA, Hildreth BE, Sharma SM, Pitarresi JR, Han L, Everett C, Koivisto C, Cuitino MC, Timmers CD, O'Quinn E, Parrish M, Romeo MJ, Linke AJ, Hobbs GA, Leone G, Guttridge DC, Zimmers TA, Lesinski GB, Ostrowski MC. STAT3 in tumor fibroblasts promotes an immunosuppressive microenvironment in pancreatic cancer. Life Sci Alliance. 2022 11; 5(11).

View in: PubMed
Dwyer JR, Racine JJ, Chapman HD, Quinlan A, Presa M, Stafford GA, Schmitz I, Serreze DV. Nfkbid Overexpression in Nonobese Diabetic Mice Elicits Complete Type 1 Diabetes Resistance in Part Associated with Enhanced Thymic Deletion of Pathogenic CD8 T Cells and Increased Numbers and Activity of Regulatory T Cells. J Immunol. 2022 07 15; 209(2):227-237.

View in: PubMed
Tibúrcio R, Narendran G, Barreto-Duarte B, Queiroz ATL, Araújo-Pereira M, Anbalagan S, Nayak K, Ravichandran N, Subramani R, Antonelli LRV, Satagopan K, Anbalagan K, Porter BO, Sher A, Swaminathan S, Sereti I, Andrade BB. Frequency of CXCR3+ CD8+ T-Lymphocyte Subsets in Peripheral Blood Is Associated With the Risk of Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome Development in Advanced HIV Disease. Front Immunol. 2022; 13:873985.

View in: PubMed
Atukorale PU, Moon TJ, Bokatch AR, Lusi CF, Routhier JT, Deng VJ, Karathanasis E. Dual agonist immunostimulatory nanoparticles combine with PD1 blockade for curative neoadjuvant immunotherapy of aggressive cancers. Nanoscale. 2022 Jan 27; 14(4):1144-1159.

View in: PubMed
Qaisar N, Arowosegbe A, Derr AG, Kucukural A, Satish B, Racicot R, Guo Z, Trombly MI, Wang JP. Type I IFN-Driven Immune Cell Dysregulation in Rat Autoimmune Diabetes. Immunohorizons. 2021 10 26; 5(10):855-869.

View in: PubMed
Tibúrcio R, Barreto-Duarte B, Naredren G, Queiroz ATL, Anbalagan S, Nayak K, Ravichandran N, Subramani R, Antonelli LRV, Satagopan K, Anbalagan K, Porter BO, Sher A, Swaminathan S, Sereti I, Andrade BB. Dynamics of T-Lymphocyte Activation Related to Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome in Persons With Advanced HIV. Front Immunol. 2021; 12:757843.

View in: PubMed
Lu YJ, Barreira-Silva P, Boyce S, Powers J, Cavallo K, Behar SM. CD4 T cell help prevents CD8 T cell exhaustion and promotes control of Mycobacterium tuberculosis infection. Cell Rep. 2021 09 14; 36(11):109696.

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Maben Z, Arya R, Georgiadis D, Stratikos E, Stern LJ. Conformational dynamics linked to domain closure and substrate binding explain the ERAP1 allosteric regulation mechanism. Nat Commun. 2021 09 06; 12(1):5302.

View in: PubMed
Fukuda K, Okamura K, Riding RL, Fan X, Afshari K, Haddadi NS, McCauley SM, Guney MH, Luban J, Funakoshi T, Yaguchi T, Kawakami Y, Khvorova A, Fitzgerald KA, Harris JE. AIM2 regulates anti-tumor immunity and is a viable therapeutic target for melanoma. J Exp Med. 2021 09 06; 218(9).

View in: PubMed
Moraschi BF, Noronha IH, Ferreira CP, Cariste LM, Monteiro CB, Denapoli P, Vrechi T, Pereira GJS, Gazzinelli RT, Lannes-Vieira J, Rodrigues MM, Bortoluci KR, Vasconcelos JRC. Rapamycin Improves the Response of Effector and Memory CD8+ T Cells Induced by Immunization With ASP2 of Trypanosoma cruzi. Front Cell Infect Microbiol. 2021; 11:676183.

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