Antimicrobial Cationic Peptides
"Antimicrobial Cationic Peptides" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Small cationic peptides that are an important component, in most species, of early innate and induced defenses against invading microbes. In animals they are found on mucosal surfaces, within phagocytic granules, and on the surface of the body. They are also found in insects and plants. Among others, this group includes the DEFENSINS, protegrins, tachyplesins, and thionins. They displace DIVALENT CATIONS from phosphate groups of MEMBRANE LIPIDS leading to disruption of the membrane.
Descriptor ID |
D023181
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MeSH Number(s) |
D12.644.050 D12.776.543.695.054
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Concept/Terms |
Antimicrobial Cationic Peptides- Antimicrobial Cationic Peptides
- Cationic Peptides, Antimicrobial
- Peptides, Antimicrobial Cationic
- Microbicidal Cationic Proteins
- Cationic Proteins, Microbicidal
- Proteins, Microbicidal Cationic
- Cationic Antimicrobial Peptides
- Antimicrobial Peptides, Cationic
- Peptides, Cationic Antimicrobial
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Below are MeSH descriptors whose meaning is more general than "Antimicrobial Cationic Peptides".
Below are MeSH descriptors whose meaning is more specific than "Antimicrobial Cationic Peptides".
This graph shows the total number of publications written about "Antimicrobial Cationic Peptides" by people in this website by year, and whether "Antimicrobial Cationic Peptides" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1981 | 0 | 1 | 1 | 1986 | 0 | 1 | 1 | 1992 | 0 | 1 | 1 | 1996 | 1 | 0 | 1 | 1999 | 0 | 1 | 1 | 2002 | 0 | 1 | 1 | 2005 | 2 | 1 | 3 | 2006 | 3 | 0 | 3 | 2007 | 2 | 0 | 2 | 2008 | 4 | 3 | 7 | 2009 | 2 | 1 | 3 | 2010 | 4 | 1 | 5 | 2011 | 2 | 0 | 2 | 2012 | 1 | 1 | 2 | 2013 | 0 | 2 | 2 | 2015 | 2 | 3 | 5 | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Antimicrobial Cationic Peptides" by people in Profiles.
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Kumar NP, Moideen K, Viswanathan V, Sivakumar S, Menon PA, Kornfeld H, Babu S. Heightened circulating levels of antimicrobial peptides in tuberculosis-Diabetes co-morbidity and reversal upon treatment. PLoS One. 2017; 12(9):e0184753.
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Levy M, Thaiss CA, Zeevi D, Dohnalová L, Zilberman-Schapira G, Mahdi JA, David E, Savidor A, Korem T, Herzig Y, Pevsner-Fischer M, Shapiro H, Christ A, Harmelin A, Halpern Z, Latz E, Flavell RA, Amit I, Segal E, Elinav E. Microbiota-Modulated Metabolites Shape the Intestinal Microenvironment by Regulating NLRP6 Inflammasome Signaling. Cell. 2015 Dec 3; 163(6):1428-43.
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Fricke WF, Song Y, Wang AJ, Smith A, Grinchuk V, Mongodin E, Pei C, Ma B, Lu N, Urban JF, Shea-Donohue T, Zhao A. Type 2 immunity-dependent reduction of segmented filamentous bacteria in mice infected with the helminthic parasite Nippostrongylus brasiliensis. Microbiome. 2015 Sep 17; 3:40.
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Miao J, Chen F, Duan S, Gao X, Liu G, Chen Y, Dixon W, Xiao H, Cao Y. iTRAQ-Based Quantitative Proteomic Analysis of the Antimicrobial Mechanism of Peptide F1 against Escherichia coli. J Agric Food Chem. 2015 Aug 19; 63(32):7190-7.
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Kishibe M, Griffin TM, Radek KA. Keratinocyte nicotinic acetylcholine receptor activation modulates early TLR2-mediated wound healing responses. Int Immunopharmacol. 2015 Nov; 29(1):63-70.
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Irazoqui JE. Why worms watch their hemidesmosomes and why you should, too. Immunity. 2015 Feb 17; 42(2):206-8.
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Sgolastra F, Deronde BM, Sarapas JM, Som A, Tew GN. Designing mimics of membrane active proteins. Acc Chem Res. 2013 Dec 17; 46(12):2977-87.
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Doyle MK, Rahman MU, Frederick B, Birbara CA, de Vries D, Toedter G, Wu X, Chen D, Ranganath VK, Westerman ME, Furst DE. Effects of subcutaneous and intravenous golimumab on inflammatory biomarkers in patients with rheumatoid arthritis: results of a phase 1, randomized, open-label trial. Rheumatology (Oxford). 2013 Jul; 52(7):1214-9.
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Ren SX, Cheng AS, To KF, Tong JH, Li MS, Shen J, Shen J, Wong CC, Zhang L, Chan RL, Wang XJ, Ng SS, Chiu LC, Marquez VE, Gallo RL, Chan FK, Yu J, Sung JJ, Wu WK, Cho CH. Host immune defense peptide LL-37 activates caspase-independent apoptosis and suppresses colon cancer. Cancer Res. 2012 Dec 15; 72(24):6512-23.
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Thaker HD, Som A, Ayaz F, Lui D, Pan W, Scott RW, Anguita J, Tew GN. Synthetic mimics of antimicrobial peptides with immunomodulatory responses. J Am Chem Soc. 2012 Jul 11; 134(27):11088-91.
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