Variant Surface Glycoproteins, Trypanosoma
"Variant Surface Glycoproteins, Trypanosoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoproteins attached to the surface coat of the trypanosome. Many of these glycoproteins show amino acid sequence diversity expressed as antigenic variations. This continuous development of antigenically distinct variants in the course of infection ensures that some trypanosomes always survive the development of immune response to propagate the infection.
Descriptor ID |
D014643
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MeSH Number(s) |
D12.776.395.550.990 D12.776.543.550.990 D23.050.293.900 D23.050.301.900
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Variant Surface Glycoproteins, Trypanosoma".
Below are MeSH descriptors whose meaning is more specific than "Variant Surface Glycoproteins, Trypanosoma".
This graph shows the total number of publications written about "Variant Surface Glycoproteins, Trypanosoma" by people in this website by year, and whether "Variant Surface Glycoproteins, Trypanosoma" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 |
2009 | 1 | 0 | 1 |
2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Variant Surface Glycoproteins, Trypanosoma" by people in Profiles.
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Bockstal V, Guirnalda P, Caljon G, Goenka R, Telfer JC, Frenkel D, Radwanska M, Magez S, Black SJ. T. brucei infection reduces B lymphopoiesis in bone marrow and truncates compensatory splenic lymphopoiesis through transitional B-cell apoptosis. PLoS Pathog. 2011 Jun; 7(6):e1002089.
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Black SJ, Guirnalda P, Frenkel D, Haynes C, Bockstal V. Induction and regulation of Trypanosoma brucei VSG-specific antibody responses. Parasitology. 2010 Dec; 137(14):2041-9.
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Black SJ, Sicard EL, Murphy N, Nolan D. Innate and acquired control of trypanosome parasitaemia in Cape buffalo. Int J Parasitol. 2001 May 01; 31(5-6):562-5.
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M?ndez S, Gurunathan S, Kamhawi S, Belkaid Y, Moga MA, Skeiky YA, Campos-Neto A, Reed S, Seder RA, Sacks D. The potency and durability of DNA- and protein-based vaccines against Leishmania major evaluated using low-dose, intradermal challenge. J Immunol. 2001 Apr 15; 166(8):5122-8.