"CD27 Ligand" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transmembrane protein belonging to the tumor necrosis factor superfamily that specifically binds to CD27 ANTIGEN. It is found on activated T-LYMPHOCYTES; B-LYMPHOCYTES; and DENDRITIC CELLS where it plays a role in stimulating the proliferation of CD4-POSITIVE T-LYMPHOCYTES and CD8-POSITIVE T-LYMPHOCYTES.
| Descriptor ID |
D053282
|
| MeSH Number(s) |
D12.644.276.374.750.030 D12.776.395.092 D12.776.467.374.750.030 D12.776.543.550.170 D23.529.374.750.030
|
| Concept/Terms |
CD27 Ligand- CD27 Ligand
- Ligand, CD27
- Antigens, CD70
- CD70 Antigens
- Tumor Necrosis Factor Ligand Superfamily Member 7
- CD27L Protein
- CD70 Antigen
- Antigen, CD70
- TNF Superfamily, Member 7
|
Below are MeSH descriptors whose meaning is more general than "CD27 Ligand".
Below are MeSH descriptors whose meaning is more specific than "CD27 Ligand".
This graph shows the total number of publications written about "CD27 Ligand" by people in this website by year, and whether "CD27 Ligand" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "CD27 Ligand" by people in Profiles.
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Ye C, Low BE, Wiles MV, Brusko TM, Serreze DV, Driver JP. CD70 Inversely Regulates Regulatory T Cells and Invariant NKT Cells and Modulates Type 1 Diabetes in NOD Mice. J Immunol. 2020 10 01; 205(7):1763-1777.
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McKinstry KK, Strutt TM, Bautista B, Zhang W, Kuang Y, Cooper AM, Swain SL. Effector CD4 T-cell transition to memory requires late cognate interactions that induce autocrine IL-2. Nat Commun. 2014 Nov 05; 5:5377.
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Driver JP, Scheuplein F, Chen YG, Grier AE, Wilson SB, Serreze DV. Invariant natural killer T-cell control of type 1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette. Diabetes. 2010 Feb; 59(2):423-32.