Cytokines

"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.

Descriptor ID	D016207
MeSH Number(s)	D12.644.276.374 D12.776.467.374 D23.529.374
Concept/Terms	Cytokines Cytokines

Below are MeSH descriptors whose meaning is more general than "Cytokines".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]

Below are MeSH descriptors whose meaning is more specific than "Cytokines".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.

Bar chart showing 709 publications over 31 distinct years, with a maximum of 39 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	4	3	7
1996	3	5	8
1997	6	6	12
1998	4	12	16
1999	5	9	14
2000	4	9	13
2001	4	8	12
2002	6	13	19
2003	8	16	24
2004	13	21	34
2005	10	23	33
2006	1	15	16
2007	4	26	30
2008	5	34	39
2009	9	24	33
2010	6	30	36
2011	8	15	23
2012	6	19	25
2013	9	27	36
2014	7	29	36
2015	5	19	24
2016	4	26	30
2017	4	15	19
2018	8	20	28
2019	3	24	27
2020	8	21	29
2021	3	24	27
2022	2	9	11
2023	3	15	18
2024	3	14	17
2025	3	10	13

Below are the most recent publications written about "Cytokines" by people in Profiles.

Gorasiya S, Mushi J, Yoganathan S, Barasa L, Pekson R, Ashby CR, Reznik SE. N,N-Diethylacetamide and N,N-Dipropylacetamide inhibit the NF-kB pathway in in vitro, ex vivo and in vivo models of inflammation-induced preterm birth. Sci Rep. 2025 Aug 14; 15(1):29861.

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Nanaware PP, Calvo-Calle JM, Redick SD, Tarpley MW, Cruz J, Clement CC, Manganaro A, Velarde de la Cruz EE, Muneeruddin K, Faulkner M, Wang JP, Shaffer SA, Harlan DM, Santambrogio L, Kent SC, Stern LJ. The antigen presentation landscape of cytokine-stressed human pancreatic islets. Cell Rep. 2025 Aug 26; 44(8):115927.

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Honwad HH, Najibi M, Shen J, Watts S, Fu AM, Koscso B, Bogunovic M, Irazoqui JE. TFEB-mediated proinflammatory response in murine macrophages induced by acute Alpha7 nicotinic receptor activation. J Leukoc Biol. 2025 Jun 04; 117(6).

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Anterasian C, Gela A, Mwambene TD, Shah JA, Ivie J, Dill-McFarland KA, Hanekom WA, Kiritsy MC, Sassetti CM, Musvosvi M, Hatherill M, Scriba TJ, Hawn TR. BCG induced innate immune response heterogeneity and susceptibility to pediatric tuberculosis. J Immunol. 2025 May 01; 214(5):936-946.

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Chubanava S, Karavaeva I, Ehrlich AM, Justicia RM, Basse AL, Kulik I, Dalbram E, Ahwazi D, Heaselgrave SR, Tro?t K, Stocks B, Hodek O, Rodrigues RN, Havelund JF, Schlabs FL, Larsen S, Yonamine CY, Henriquez-Olgu?n C, Giustarini D, Rossi R, Gerhart-Hines Z, Moritz T, Zierath JR, Sakamoto K, Jensen TE, F?rgeman NJ, Lavery GG, Deshmukh AS, Treebak JT. NAD depletion in skeletal muscle does not compromise muscle function or accelerate aging. Cell Metab. 2025 Jul 01; 37(7):1460-1481.e17.

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Avouac J, Kay J, Choy E. Personalised treatment of rheumatoid arthritis based on cytokine profiles and synovial tissue signatures: potentials and challenges. Semin Arthritis Rheum. 2025 Aug; 73:152740.

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Hasanvand A, Ghandinezhad M, Nourmohammadi M, Hatami F, Beiranvand B, Haghighatian Z, Amanolahi Baharvand P, Kharazmkia A. Investigating the role of the AMPK signaling pathway in preventing CCI-induced neuropathy in rats: focus on anti-inflammatory effects. Neurol Res. 2025 Jun; 47(6):494-503.

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Chang E, Cavallo K, Behar SM. CD4 T cell dysfunction is associated with bacterial recrudescence during chronic tuberculosis. Nat Commun. 2025 Mar 17; 16(1):2636.

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Burns BA, Shaw CA, Chandra M, Forconi CS, Moormann AM, Konduri V, Tubman VN, Decker WK. Comprehensive normalization and binary classification methods for enhanced sensitivity and reproducibility in Luminex assay quantitation. J Immunol Methods. 2025 Mar; 538:113826.

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Krajewski D, Ranjitkar S, Jordan N, Schneider SS, Mathias CB. IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy. Front Immunol. 2025; 16:1526498.

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