Cytokines

"Cytokines" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner.

Descriptor ID	D016207
MeSH Number(s)	D12.644.276.374 D12.776.467.374 D23.529.374
Concept/Terms	Cytokines Cytokines

Below are MeSH descriptors whose meaning is more general than "Cytokines".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]

Below are MeSH descriptors whose meaning is more specific than "Cytokines".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cytokines" by people in this website by year, and whether "Cytokines" was a major or minor topic of these publications.

Bar chart showing 683 publications over 31 distinct years, with a maximum of 36 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	5	3	8
1996	3	3	6
1997	7	7	14
1998	6	12	18
1999	7	9	16
2000	7	9	16
2001	6	8	14
2002	7	14	21
2003	8	16	24
2004	14	21	35
2005	11	24	35
2006	1	15	16
2007	4	25	29
2008	3	32	35
2009	9	23	32
2010	6	30	36
2011	7	15	22
2012	5	17	22
2013	9	26	35
2014	7	26	33
2015	4	18	22
2016	5	24	29
2017	4	14	18
2018	7	17	24
2019	3	22	25
2020	8	21	29
2021	3	23	26
2022	1	8	9
2023	2	14	16
2024	3	13	16
2025	0	2	2

Below are the most recent publications written about "Cytokines" by people in Profiles.

Arowosegbe A, Guo Z, Vanderleeden E, Derr AG, Wang JP. Janus kinase inhibition prevents autoimmune diabetes in LEW.1WR1 rats. J Autoimmun. 2025 Feb; 151:103358.

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Mohammadhosseini M, Enright T, Duvall A, Chitsazan A, Lin HY, Ors A, Davis BA, Nikolova O, Bresciani E, Diemer J, Craft K, Menezes AC, Merguerian M, Chong S, Calvo KR, Deuitch NT, Glushakow-Smith S, Gritsman K, Godley LA, Horwitz MS, Keel S, Castilla LH, Demir E, Mohammed H, Liu P, Agarwal A. Targeting the CD74 signaling axis suppresses inflammation and rescues defective hematopoiesis in RUNX1-familial platelet disorder. Sci Transl Med. 2025 Jan 08; 17(780):eadn9832.

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Kellogg TD, Ceglia S, Mortzfeld BM, Tanna TM, Zeamer AL, Mancini MR, Foley SE, Ward DV, Bhattarai SK, McCormick BA, Reboldi A, Bucci V. Succinate-producing microbiota drives tuft cell hyperplasia to protect against Clostridioides difficile. J Exp Med. 2025 Jan 06; 222(1).

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Rabin A, Bello E, Kumar S, Zeki DA, Afshari K, Deshpande M, Francis N, Khalighinejad F, Umeton R, Radu I, Qutab F, Kwong D, Kurban M, Hemond C, Richmond JM, Ionete C. Targeted proteomics of cerebrospinal fluid in treatment na?ve multiple sclerosis patients identifies immune biomarkers of clinical phenotypes. Sci Rep. 2024 09 18; 14(1):21793.

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Latz C, Licht A, Mirshahi A, Latz E, Zimmer K. Prospective Cytokine Profiling in Aqueous Humor Reveals a Proinflammatory Microenvironment in Highly Dense Nuclear Cataracts. Invest Ophthalmol Vis Sci. 2024 Sep 03; 65(11):25.

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Rajamanickam A, Kothandaraman SP, Kumar NP, Viswanathan V, Shanmugam S, Hissar S, Nott S, Kornfeld H, Babu S. Cytokine and chemokine profiles in pulmonary tuberculosis with pre-diabetes. Front Immunol. 2024; 15:1447161.

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Kane GI, Brassil ML, Diaz-Infante MB, Atukorale PU. Nanocarrier design for pathogen-inspired innate immune agonist delivery. Trends Immunol. 2024 Sep; 45(9):678-692.

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Wang X, Campbell B, Bodogai M, McDevitt RA, Patrikeev A, Gusev F, Ragonnaud E, Kumaraswami K, Shirenova S, Vardy K, Alameh MG, Weissman D, Ishikawa-Ankerhold H, Okun E, Rogaev E, Biragyn A. CD8+ T cells exacerbate AD-like symptoms in mouse model of amyloidosis. Brain Behav Immun. 2024 Nov; 122:444-455.

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Qiu Z, Xiang L, Han Y, Zhang B, Qiao X, Zheng Z, Xiao H. Structure-anti-inflammatory activity relationship of garlic fructans in mice with dextran sulfate sodium-induced colitis: Impact of chain length. Carbohydr Polym. 2024 Dec 15; 346:122582.

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Mandrekar P, Mandal A. Pathogenesis of Alcohol-Associated Liver Disease. Clin Liver Dis. 2024 Nov; 28(4):647-661.

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