Proteostasis Deficiencies
"Proteostasis Deficiencies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Disorders caused by imbalances in the PROTEIN HOMEOSTASIS network - synthesis, folding, and transport of proteins; post-translational modifications; and degradation or clearance of misfolded proteins.
| Descriptor ID |
D057165
|
| MeSH Number(s) |
C18.452.845
|
| Concept/Terms |
Proteostasis Deficiencies- Proteostasis Deficiencies
- Deficiencies, Proteostasis
- Deficiency, Proteostasis
- Proteostasis Deficiency
- Proteostasis Dysfunctions
- Dysfunction, Proteostasis
- Dysfunctions, Proteostasis
- Proteostasis Dysfunction
Protein Misfolding Disorders- Protein Misfolding Disorders
- Disorder, Protein Misfolding
- Disorders, Protein Misfolding
- Misfolding Disorder, Protein
- Misfolding Disorders, Protein
- Protein Misfolding Disorder
- Protein Folding Disorders
- Disorder, Protein Folding
- Disorders, Protein Folding
- Folding Disorder, Protein
- Folding Disorders, Protein
- Protein Folding Disorder
- Protein Folding Diseases
- Disease, Protein Folding
- Diseases, Protein Folding
- Folding Disease, Protein
- Folding Diseases, Protein
- Protein Folding Disease
- Protein Misfolding Diseases
- Disease, Protein Misfolding
- Diseases, Protein Misfolding
- Misfolding Disease, Protein
- Misfolding Diseases, Protein
- Protein Misfolding Disease
|
Below are MeSH descriptors whose meaning is more general than "Proteostasis Deficiencies".
Below are MeSH descriptors whose meaning is more specific than "Proteostasis Deficiencies".
This graph shows the total number of publications written about "Proteostasis Deficiencies" by people in this website by year, and whether "Proteostasis Deficiencies" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proteostasis Deficiencies" by people in Profiles.
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Schmidt EJ, Funes S, McKeon JE, Morgan BR, Boopathy S, O'Connor LC, Bilsel O, Massi F, J?gou A, Bosco DA. ALS-linked PFN1 variants exhibit loss and gain of functions in the context of formin-induced actin polymerization. Proc Natl Acad Sci U S A. 2021 06 08; 118(23).
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Lamech LT, Haynes CM. The unpredictability of prolonged activation of stress response pathways. J Cell Biol. 2015 Jun 22; 209(6):781-7.
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Bouchecareilh M, Hutt DM, Szajner P, Flotte TR, Balch WE. Histone deacetylase inhibitor (HDACi) suberoylanilide hydroxamic acid (SAHA)-mediated correction of a1-antitrypsin deficiency. J Biol Chem. 2012 Nov 02; 287(45):38265-78.
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Bosco DA, Morfini G, Karabacak NM, Song Y, Gros-Louis F, Pasinelli P, Goolsby H, Fontaine BA, Lemay N, McKenna-Yasek D, Frosch MP, Agar JN, Julien JP, Brady ST, Brown RH. Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS. Nat Neurosci. 2010 Nov; 13(11):1396-403.