Motor Neurons

"Motor Neurons" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Neurons which activate MUSCLE CELLS.

Descriptor ID	D009046
MeSH Number(s)	A08.675.655.500 A11.671.655.500
Concept/Terms	Motor Neurons Motor Neurons Motor Neuron Neuron, Motor Neurons, Motor Motoneurons Motoneuron Motor Neurons, Alpha Motor Neurons, Alpha Alpha Motor Neuron Alpha Motor Neurons Motor Neuron, Alpha Neuron, Alpha Motor Neurons, Alpha Motor Alpha Motorneurons Alpha Motorneuron Motorneuron, Alpha Motorneurons, Alpha

Below are MeSH descriptors whose meaning is more general than "Motor Neurons".

Anatomy [A]
Nervous System [A08]
Neurons [A08.675]
Neurons, Efferent [A08.675.655]
Motor Neurons [A08.675.655.500]
Cells [A11]
Neurons [A11.671]
Neurons, Efferent [A11.671.655]
Motor Neurons [A11.671.655.500]

Below are MeSH descriptors whose meaning is related to "Motor Neurons".

Below are MeSH descriptors whose meaning is more specific than "Motor Neurons".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Motor Neurons" by people in this website by year, and whether "Motor Neurons" was a major or minor topic of these publications.

Bar chart showing 150 publications over 31 distinct years, with a maximum of 12 publications in 2008 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	2	1	3
1996	1	1	2
1997	1	0	1
1998	2	1	3
1999	1	3	4
2000	1	2	3
2001	2	0	2
2002	5	0	5
2003	0	3	3
2004	4	0	4
2005	6	2	8
2006	4	3	7
2007	1	1	2
2008	11	1	12
2009	2	4	6
2010	2	2	4
2011	4	1	5
2012	4	3	7
2013	6	6	12
2014	3	2	5
2015	2	3	5
2016	5	2	7
2017	3	3	6
2018	2	3	5
2019	3	1	4
2020	1	2	3
2021	0	3	3
2022	0	6	6
2023	0	5	5
2024	2	4	6
2025	1	1	2

Below are the most recent publications written about "Motor Neurons" by people in Profiles.

Masegosa VM, Fritz E, Corvalan D, Rojas F, Garc?s P, Navarro X, Bloms-Funke P, van Zundert B, Herrando-Grabulosa M. Novel Dual Mechanism GRT-X Agonist Acting on Kv7 Potassium Channel/Translocator Protein Receptor Prevents Motoneuron Degeneration Following Exposure to Mouse and Human Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Astrocyte-Conditioned Media. ACS Chem Neurosci. 2025 Aug 06; 16(15):2887-2900.

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Weiss A, Gilbert JW, Rivera Flores IV, Belgrad J, Ferguson C, Dogan EO, Wightman N, Mocarski K, Echeverria D, Harkins AL, Summers A, Bramato B, McHugh N, Furgal R, Yamada N, Cooper D, Monopoli K, Godinho BMDC, Hassler MR, Yamada K, Greer P, Henninger N, Brown RH, Khvorova A. RNAi-mediated silencing of SOD1 profoundly extends survival and functional outcomes in ALS mice. Mol Ther. 2025 Aug 06; 33(8):3917-3938.

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Buckley M, Jacob WP, Bortey L, McClain ME, Ritter AL, Godfrey A, Munneke AS, Ramachandran S, Kenis S, Kolnik JC, Olofsson S, Nenadovich M, Kutoloski T, Rademacher L, Alva A, Heinecke O, Adkins R, Parkar S, Bhagat R, Lunato J, Beets I, Francis MM, Kowalski JR. Cell non-autonomous signaling through the conserved C. elegans glycoprotein hormone receptor FSHR-1 regulates cholinergic neurotransmission. PLoS Genet. 2024 Nov; 20(11):e1011461.

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Mart?nez P, Silva M, Abarz?a S, Tevy MF, Jaimovich E, Constantine-Paton M, Bustos FJ, van Zundert B. Skeletal myotubes expressing ALS mutant SOD1 induce pathogenic changes, impair mitochondrial axonal transport, and trigger motoneuron death. Mol Med. 2024 Oct 25; 30(1):185.

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Halim DO, Krishnan G, Hass EP, Lee S, Verma M, Almeida S, Gu Y, Kwon DY, Fazzio TG, Gao FB. The exocyst subunit EXOC2 regulates the toxicity of expanded GGGGCC repeats in C9ORF72-ALS/FTD. Cell Rep. 2024 07 23; 43(7):114375.

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Wirthlin ME, Schmid TA, Elie JE, Zhang X, Kowalczyk A, Redlich R, Shvareva VA, Rakuljic A, Ji MB, Bhat NS, Kaplow IM, Sch?ffer DE, Lawler AJ, Wang AZ, Phan BN, Annaldasula S, Brown AR, Lu T, Lim BK, Azim E, Clark NL, Meyer WK, Pond SLK, Chikina M, Yartsev MM, Pfenning AR, Andrews G, Armstrong JC, Bianchi M, Birren BW, Bredemeyer KR, Breit AM, Christmas MJ, Clawson H, Damas J, Di Palma F, Diekhans M, Dong MX, Eizirik E, Fan K, Fanter C, Foley NM, Forsberg-Nilsson K, Garcia CJ, Gatesy J, Gazal S, Genereux DP, Goodman L, Grimshaw J, Halsey MK, Harris AJ, Hickey G, Hiller M, Hindle AG, Hubley RM, Hughes GM, Johnson J, Juan D, Kaplow IM, Karlsson EK, Keough KC, Kirilenko B, Koepfli KP, Korstian JM, Kowalczyk A, Kozyrev SV, Lawler AJ, Lawless C, Lehmann T, Levesque DL, Lewin HA, Li X, Lind A, Lindblad-Toh K, Mackay-Smith A, Marinescu VD, Marques-Bonet T, Mason VC, Meadows JRS, Meyer WK, Moore JE, Moreira LR, Moreno-Santillan DD, Morrill KM, Muntan? G, Murphy WJ, Navarro A, Nweeia M, Ortmann S, Osmanski A, Paten B, Paulat NS, Pfenning AR, Phan BN, Pollard KS, Pratt HE, Ray DA, Reilly SK, Rosen JR, Ruf I, Ryan L, Ryder OA, Sabeti PC, Sch?ffer DE, Serres A, Shapiro B, Smit AFA, Springer M, Srinivasan C, Steiner C, Storer JM, Sullivan KAM, Sullivan PF, Sundstr?m E, Supple MA, Swofford R, Talbot JE, Teeling E, Turner-Maier J, Valenzuela A, Wagner F, Wallerman O, Wang C, Wang J, Weng Z, Wilder AP, Wirthlin ME, Xue JR, Zhang X. Vocal learning-associated convergent evolution in mammalian proteins and regulatory elements. Science. 2024 03 29; 383(6690):eabn3263.

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Carmona LM, Thomas ED, Smith K, Tasic B, Costa RM, Nelson A. Topographical and cell type-specific connectivity of rostral and caudal forelimb corticospinal neuron populations. Cell Rep. 2024 04 23; 43(4):113993.

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Xie Q, Chen X, Ma H, Zhu Y, Ma Y, Jalinous L, Cox GF, Weaver F, Yang J, Kennedy Z, Gruntman A, Du A, Su Q, He R, Tai PW, Gao G, Xie J. Improved gene therapy for spinal muscular atrophy in mice using codon-optimized hSMN1 transgene and hSMN1 gene-derived promotor. EMBO Mol Med. 2024 Apr; 16(4):945-965.

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Mann JR, McKenna ED, Mawrie D, Papakis V, Alessandrini F, Anderson EN, Mayers R, Ball HE, Kaspi E, Lubinski K, Baron DM, Tellez L, Landers JE, Pandey UB, Kiskinis E. Loss of function of the ALS-associated NEK1 kinase disrupts microtubule homeostasis and nuclear import. Sci Adv. 2023 08 18; 9(33):eadi5548.

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Gromova A, Cha B, Robinson EM, Strickland LM, Nguyen N, ElMallah MK, Cortes CJ, La Spada AR. X-linked SBMA model mice display relevant non-neurological phenotypes and their expression of mutant androgen receptor protein in motor neurons is not required for neuromuscular disease. Acta Neuropathol Commun. 2023 06 02; 11(1):90.

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