Iron Chelating Agents

"Iron Chelating Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Organic chemicals that form two or more coordination links with an iron ion. Once coordination has occurred, the complex formed is called a chelate. The iron-binding porphyrin group of hemoglobin is an example of a metal chelate found in biological systems.

Descriptor ID	D007502
MeSH Number(s)	D27.505.519.914.500.410 D27.720.832.500.410
Concept/Terms	Iron Chelating Agents Iron Chelating Agents Agents, Iron Chelating Chelating Agents, Iron Iron Chelates Chelates, Iron

Below are MeSH descriptors whose meaning is more general than "Iron Chelating Agents".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Sequestering Agents [D27.505.519.914]
Chelating Agents [D27.505.519.914.500]
Iron Chelating Agents [D27.505.519.914.500.410]
Specialty Uses of Chemicals [D27.720]
Sequestering Agents [D27.720.832]
Chelating Agents [D27.720.832.500]
Iron Chelating Agents [D27.720.832.500.410]

Below are MeSH descriptors whose meaning is related to "Iron Chelating Agents".

Below are MeSH descriptors whose meaning is more specific than "Iron Chelating Agents".

Iron Chelating Agents
Siderophores

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Iron Chelating Agents" by people in this website by year, and whether "Iron Chelating Agents" was a major or minor topic of these publications.

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Below are the most recent publications written about "Iron Chelating Agents" by people in Profiles.

Taher AT, Saliba AN, Kuo KH, Giardina PJ, Cohen AR, Neufeld EJ, Aydinok Y, Kwiatkowski JL, Jeglinski BI, Pietropaolo K, Berk G, Viprakasit V. Safety and pharmacokinetics of the oral iron chelator SP-420 in ?-thalassemia. Am J Hematol. 2017 Dec; 92(12):1356-1361.

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Thompson AA, Kim HY, Singer ST, Vichinsky E, Eile J, Yamashita R, Giardina PJ, Olivieri N, Parmar N, Trachtenberg F, Neufeld EJ, Kwiatkowski JL. Pregnancy outcomes in women with thalassemia in North America and the United Kingdom. Am J Hematol. 2013 Sep; 88(9):771-3.

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Ambati SR, Randolph RE, Mennitt K, Kleinert DA, Weinsaft JW, Giardina PJ. Longitudinal monitoring of cardiac siderosis using cardiovascular magnetic resonance T2* in patients with thalassemia major on various chelation regimens: a 6-year study. Am J Hematol. 2013 Aug; 88(8):652-6.

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Porter JB, Wood J, Olivieri N, Vichinsky EP, Taher A, Neufeld E, Giardina P, Thompson A, Moore B, Evans P, Kim HY, Macklin EA, Trachtenberg F. Treatment of heart failure in adults with thalassemia major: response in patients randomised to deferoxamine with or without deferiprone. J Cardiovasc Magn Reson. 2013 May 20; 15:38.

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Goldberg SL, Giardina PJ, Chirnomas D, Esposito J, Paley C, Vichinsky E. The palatability and tolerability of deferasirox taken with different beverages or foods. Pediatr Blood Cancer. 2013 Sep; 60(9):1507-12.

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Grady RW, Galanello R, Randolph RE, Kleinert DA, Dessi C, Giardina PJ. Toward optimizing the use of deferasirox: potential benefits of combined use with deferoxamine. Haematologica. 2013 Jan; 98(1):129-35.

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Kwiatkowski JL, Kim HY, Thompson AA, Quinn CT, Mueller BU, Odame I, Giardina PJ, Vichinsky EP, Boudreaux JM, Cohen AR, Porter JB, Coates T, Olivieri NF, Neufeld EJ. Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort. Blood. 2012 Mar 22; 119(12):2746-53.

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Trachtenberg F, Vichinsky E, Haines D, Pakbaz Z, Mednick L, Sobota A, Kwiatkowski J, Thompson AA, Porter J, Coates T, Giardina PJ, Olivieri N, Yamashita R, Neufeld EJ. Iron chelation adherence to deferoxamine and deferasirox in thalassemia. Am J Hematol. 2011 May; 86(5):433-6.

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Wood JC, Glynos T, Thompson A, Giardina P, Harmatz P, Kang BP, Paley C, Coates TD. Relationship between labile plasma iron, liver iron concentration and cardiac response in a deferasirox monotherapy trial. Haematologica. 2011 Jul; 96(7):1055-8.

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Wood JC, Glynos T, Thompson A, Giardina P, Harmatz P, Kang BP, Paley C, Coates TD. Follow-up report on the 2-year cardiac data from a deferasirox monotherapy trial. Am J Hematol. 2010 Oct; 85(10):818-9.

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