PAX5 Transcription Factor

"PAX5 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A paired box transcription factor that is essential for CELL DIFFERENTIATION of B-LYMPHOCYTES. It functions both as a transcriptional activator and repressor to mediate B-cell commitment.

Descriptor ID	D051757
MeSH Number(s)	D12.776.260.645.500 D12.776.930.700.500
Concept/Terms	PAX5 Transcription Factor PAX5 Transcription Factor Transcription Factor, PAX5 B-Cell-Specific Activator Protein B Cell Specific Activator Protein Transcription Factor PAX5 PAX5, Transcription Factor Paired Box 5 Protein B Cell-Specific Transcription Factor B Cell Specific Transcription Factor Early B Cell-Specific Binding Protein-1 Early B Cell Specific Binding Protein 1 Pax5A Transcription Factor Pax5A Transcription Factor Transcription Factor, Pax5A

Below are MeSH descriptors whose meaning is more general than "PAX5 Transcription Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Paired Box Transcription Factors [D12.776.260.645]
PAX5 Transcription Factor [D12.776.260.645.500]
Transcription Factors [D12.776.930]
Paired Box Transcription Factors [D12.776.930.700]
PAX5 Transcription Factor [D12.776.930.700.500]

Below are MeSH descriptors whose meaning is related to "PAX5 Transcription Factor".

Below are MeSH descriptors whose meaning is more specific than "PAX5 Transcription Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "PAX5 Transcription Factor" by people in this website by year, and whether "PAX5 Transcription Factor" was a major or minor topic of these publications.

Bar chart showing 7 publications over 6 distinct years, with a maximum of 2 publications in 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2006	0	1	1
2011	1	0	1
2012	0	2	2
2016	0	1	1
2017	1	0	1
2019	0	1	1

Below are the most recent publications written about "PAX5 Transcription Factor" by people in Profiles.

Viny AD, Bowman RL, Liu Y, Lavall?e VP, Eisman SE, Xiao W, Durham BH, Navitski A, Park J, Braunstein S, Alija B, Karzai A, Csete IS, Witkin M, Azizi E, Baslan T, Ott CJ, Pe'er D, Dekker J, Koche R, Levine RL. Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation. Cell Stem Cell. 2019 11 07; 25(5):682-696.e8.

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Rozenvald IB, Richardson MD, Brock L, Maiese RL. Immunohistochemical Detection of Hairy Cell Leukemia in Paraffin Sections: The Role of Pax5 and CD103 Double Staining to Improve Specificity and Sensitivity. Arch Pathol Lab Med. 2017 Jun; 141(6):837-840.

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Montefiori L, Wuerffel R, Roqueiro D, Lajoie B, Guo C, Gerasimova T, De S, Wood W, Becker KG, Dekker J, Liang J, Sen R, Kenter AL. Extremely Long-Range Chromatin Loops Link Topological Domains to Facilitate a Diverse Antibody Repertoire. Cell Rep. 2016 Feb 02; 14(4):896-906.

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Morgan EA, Pozdnyakova O, Nascimento AF, Hirsch MS. PAX8 and PAX5 are differentially expressed in B-cell and T-cell lymphomas. Histopathology. 2013 Feb; 62(3):406-13.

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Zhang H, Peng C, Hu Y, Li H, Sheng Z, Chen Y, Sullivan C, Cerny J, Hutchinson L, Higgins A, Miron P, Zhang X, Brehm MA, Li D, Green MR, Li S. The Blk pathway functions as a tumor suppressor in chronic myeloid leukemia stem cells. Nat Genet. 2012 Jul 15; 44(8):861-71.

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Loo SK, Shtir C, Doyle AE, Mick E, McGough JJ, McCracken J, Biederman J, Smalley SL, Cantor RM, Faraone SV, Nelson SF. Genome-wide association study of intelligence: additive effects of novel brain expressed genes. J Am Acad Child Adolesc Psychiatry. 2012 Apr; 51(4):432-440.e2.

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Hure MC, Elco CP, Ward D, Hutchinson L, Meng X, Dorfman DM, Yu H. Histiocytic sarcoma arising from clonally related mantle cell lymphoma. J Clin Oncol. 2012 Feb 10; 30(5):e49-53.

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Bradley SP, Kaminski DA, Peters AH, Jenuwein T, Stavnezer J. The histone methyltransferase Suv39h1 increases class switch recombination specifically to IgA. J Immunol. 2006 Jul 15; 177(2):1179-88.

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Maier H, Colbert J, Fitzsimmons D, Clark DR, Hagman J. Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site. Mol Cell Biol. 2003 Mar; 23(6):1946-60.

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