"Receptors, Eph Family" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this family of proteins derives from original protein Eph (now called the EPHA1 RECEPTOR), which was named after the cell line it was first discovered in: Erythropoietin-Producing human Hepatocellular carcinoma cell line. Members of this family have been implicated in regulation of cell-cell interactions involved in nervous system patterning and development.
Descriptor ID |
D036081
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MeSH Number(s) |
D08.811.913.696.620.682.725.400.850 D12.776.543.750.630.500
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Concept/Terms |
Receptors, Eph Family- Receptors, Eph Family
- Eph Family Receptors
- Ephrin Receptors
- Receptors, Ephrin
- Eph Receptor Tyrosine Kinase
- Eph Receptors
- Receptors, Eph
Ephrin B Receptors- Ephrin B Receptors
- EphB Receptors
- Receptors, EphB
- EphB Receptor
- Ephrin B Receptor
- Receptor, Ephrin B
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Below are MeSH descriptors whose meaning is more general than "Receptors, Eph Family".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Eph Family".
- Receptors, Eph Family
- Receptor, EphA1
- Receptor, EphA2
- Receptor, EphA3
- Receptor, EphA4
- Receptor, EphA5
- Receptor, EphA6
- Receptor, EphA7
- Receptor, EphA8
- Receptor, EphB1
- Receptor, EphB2
- Receptor, EphB3
- Receptor, EphB4
- Receptor, EphB5
This graph shows the total number of publications written about "Receptors, Eph Family" by people in this website by year, and whether "Receptors, Eph Family" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2005 | 1 | 1 | 2 |
2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Eph Family" by people in Profiles.
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Margolis SS, Salogiannis J, Lipton DM, Mandel-Brehm C, Wills ZP, Mardinly AR, Hu L, Greer PL, Bikoff JB, Ho HY, Soskis MJ, Sahin M, Greenberg ME. EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation. Cell. 2010 Oct 29; 143(3):442-55.
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Egea J, Nissen UV, Dufour A, Sahin M, Greer P, Kullander K, Mrsic-Flogel TD, Greenberg ME, Kiehn O, Vanderhaeghen P, Klein R. Regulation of EphA 4 kinase activity is required for a subset of axon guidance decisions suggesting a key role for receptor clustering in Eph function. Neuron. 2005 Aug 18; 47(4):515-28.
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Cowan CW, Shao YR, Sahin M, Shamah SM, Lin MZ, Greer PL, Gao S, Griffith EC, Brugge JS, Greenberg ME. Vav family GEFs link activated Ephs to endocytosis and axon guidance. Neuron. 2005 Apr 21; 46(2):205-17.
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Vergara-Silva A, Schaefer KL, Berg LJ. Compartmentalized Eph receptor and ephrin expression in the thymus. Gene Expr Patterns. 2002 Dec; 2(3-4):261-5.
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Vergara-Silva A, Schaefer KL, Berg LJ. Compartmentalized Eph receptor and ephrin expression in the thymus. Mech Dev. 2002 Dec; 119 Suppl 1:S225-9.