"Lethal Dose 50" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
Descriptor ID |
D007928
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MeSH Number(s) |
E05.940.402 G07.225.500 G07.690.773.875.750 G07.690.936.500.750
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Lethal Dose 50".
Below are MeSH descriptors whose meaning is more specific than "Lethal Dose 50".
This graph shows the total number of publications written about "Lethal Dose 50" by people in this website by year, and whether "Lethal Dose 50" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2010 | 0 | 1 | 1 |
2011 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lethal Dose 50" by people in Profiles.
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Gao X, Wang Q, Wang J, Wang C, Lu L, Gao R, Huan F, Dixon D, Xiao H. Expression of calmodulin in germ cells is associated with fenvalerate-induced male reproductive toxicity. Arch Toxicol. 2012 Sep; 86(9):1443-51.
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Wang S, Goguen JD, Li F, Lu S. Involvement of CD8+ T cell-mediated immune responses in LcrV DNA vaccine induced protection against lethal Yersinia pestis challenge. Vaccine. 2011 Sep 09; 29(39):6802-9.
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Gresham C, Rosenbaum C, Gaspari RJ, Jackson CJ, Bird SB. Kinetics and efficacy of an organophosphorus hydrolase in a rodent model of methyl-parathion poisoning. Acad Emerg Med. 2010 Jul; 17(7):736-40.
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Bischof LJ, Huffman DL, Aroian RV. Assays for toxicity studies in C. elegans with Bt crystal proteins. Methods Mol Biol. 2006; 351:139-54.
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Gravekamp C, Rosner B, Madoff LC. Deletion of repeats in the alpha C protein enhances the pathogenicity of group B streptococci in immune mice. Infect Immun. 1998 Sep; 66(9):4347-54.
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Dezube BJ, Ahlers CM, Lawrence JP, Teng EI, Silberman SL, Pardee AB, Finberg RW. Tenidap inhibits replication of the human immunodeficiency virus-1 in cultured cells. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Jan 01; 14(1):13-7.
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Timofeev BA, Bolotin IM, Stepanova LP, Bogdanov AA, Georgiu K, Malyshev SN, Petrovsky VV, Klibanov AL, Torchilin VP. Liposomal diamidine (imidocarb): preparation and animal studies. J Microencapsul. 1994 Nov-Dec; 11(6):627-32.
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Moonis M, Ahmad I, Bachhawat BK. Effect of elimination of phagocytic cells by liposomal dichloromethylene diphosphonate on aspergillosis virulence and toxicity of liposomal amphotericin B in mice. J Antimicrob Chemother. 1994 Mar; 33(3):571-83.
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Moonis M, Ahmad I, Bachhawat BK. Liposomal hamycin in the control of experimental aspergillosis in mice: effect of phosphatidic acid with and without cholesterol. J Antimicrob Chemother. 1993 Apr; 31(4):569-79.
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Moonis M, Ahmad I, Bachhawat BK. Mannosylated liposomes as carriers for hamycin in the treatment of experimental aspergillosis in Balb/C mice. J Drug Target. 1993; 1(2):147-55.