Endoplasmic Reticulum

"Endoplasmic Reticulum" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A system of cisternae in the CYTOPLASM of many cells. In places the endoplasmic reticulum is continuous with the plasma membrane (CELL MEMBRANE) or outer membrane of the nuclear envelope. If the outer surfaces of the endoplasmic reticulum membranes are coated with ribosomes, the endoplasmic reticulum is said to be rough-surfaced (ENDOPLASMIC RETICULUM, ROUGH); otherwise it is said to be smooth-surfaced (ENDOPLASMIC RETICULUM, SMOOTH). (King & Stansfield, A Dictionary of Genetics, 4th ed)

Descriptor ID	D004721
MeSH Number(s)	A11.284.430.214.190.875.248
Concept/Terms	Endoplasmic Reticulum Endoplasmic Reticulum Reticulum, Endoplasmic Ergastoplasm

Below are MeSH descriptors whose meaning is more general than "Endoplasmic Reticulum".

Anatomy [A]
Cells [A11]
Cellular Structures [A11.284]
Intracellular Space [A11.284.430]
Cytoplasm [A11.284.430.214]
Cytoplasmic Structures [A11.284.430.214.190]
Organelles [A11.284.430.214.190.875]
Endoplasmic Reticulum [A11.284.430.214.190.875.248]

Below are MeSH descriptors whose meaning is related to "Endoplasmic Reticulum".

Below are MeSH descriptors whose meaning is more specific than "Endoplasmic Reticulum".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Endoplasmic Reticulum" by people in this website by year, and whether "Endoplasmic Reticulum" was a major or minor topic of these publications.

Bar chart showing 135 publications over 28 distinct years, with a maximum of 10 publications in 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
2000	0	1	1
2001	1	2	3
2002	1	2	3
2003	3	3	6
2004	4	2	6
2005	3	5	8
2006	3	5	8
2007	2	1	3
2008	3	6	9
2009	3	4	7
2010	6	3	9
2011	1	4	5
2012	3	4	7
2013	1	6	7
2014	3	3	6
2015	2	1	3
2016	1	3	4
2017	3	3	6
2018	2	3	5
2019	4	6	10
2020	0	1	1
2021	2	3	5
2022	0	3	3
2023	2	0	2
2024	2	1	3
2025	0	1	1
2026	1	2	3

Below are the most recent publications written about "Endoplasmic Reticulum" by people in Profiles.

Wang R, Fortier TM, Sun X, Chai F, Velentzas PD, Baehrecke EH. Cholesterol transfer proteins promote Atg-independent ER clearance by lysosomes. Cell Rep. 2026 Jun 23; 45(6):117537.

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Chacon-Millan P, Delicato A, Mahmood A, Tirozzi A, Monfregola J, Duroure K, Serafini M, Kroll F, El-Hage O, Salah S, Atawneh OM, Atik T, Durmusalioglu EA, Isik E, Almontashiri NAM, Tabarki B, Kanaan M, Rabie G, Torella A, Spampanato C, Battaglia DI, Begemann A, Steindl K, Rauch A, Zweier M, Hajianpour M, Brigatti KW, Alhashem A, Maroofian R, Feigerlova E, Lambert L, Feillet F, Abbott MA, D'Alessio AM, Gonzaga-Jauregui C, Tawk M, De Matteis MA, Del Bene F, Zollino M, Nigro V, Venditti R, Franco B, Morleo M. Bi-allelic loss-of-function variants in JKAMP cause a neurodevelopmental syndrome associated with dysregulation of GPR37 trafficking. Am J Hum Genet. 2026 Mar 05; 113(3):562-581.

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Suthar KP, Hounsell C, Fan Y, Bergmann A. Calcium signaling regulates apoptosis-induced proliferation in Drosophila. PLoS Biol. 2026 Jan; 24(1):e3003607.

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Pham TG, Ajayi O, He J, Sagarbarria I, Hardy JA, Wu J. Orthogonal RNA-regulated destabilization domains for three-color RNA imaging with minimal RNA perturbation. Nat Methods. 2026 Jan; 23(1):165-174.

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Fu Q, Wang Y, Qin J, Xie D, McNally D, Yoon S. Enhanced ER protein processing gene expression increases rAAV yield and full capsid ratio in HEK293 cells. Appl Microbiol Biotechnol. 2024 Sep 04; 108(1):459.

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Williams RV, Guay KP, Hurlbut Lesk OA, Clerico EM, Hebert DN, Gierasch LM. Insights into the interaction between UGGT, the gatekeeper of folding in the ER, and its partner, the selenoprotein SEP15. Proc Natl Acad Sci U S A. 2024 08 20; 121(34):e2315009121.

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Restrepo LJ, Baehrecke EH. Regulation and Functions of Autophagy During Animal Development. J Mol Biol. 2024 08 01; 436(15):168473.

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Wang R, Fortier TM, Chai F, Miao G, Shen JL, Restrepo LJ, DiGiacomo JJ, Velentzas PD, Baehrecke EH. PINK1, Keap1, and Rtnl1 regulate selective clearance of endoplasmic reticulum during development. Cell. 2023 09 14; 186(19):4172-4188.e18.

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Phoomak C, Rinis N, Baro M, Shrimal S, Bennett D, Shaffer SA, Lehrman M, Gilmore R, Contessa JN. Signal recognition particle receptor-? (SR-?) coordinates cotranslational N-glycosylation. Sci Adv. 2023 03 17; 9(11):eade8079.

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Arya R, Maben Z, Rane D, Ali A, Stern LJ. Phenylsulfamoyl Benzoic Acid Inhibitor of ERAP2 with a Novel Mode of Inhibition. ACS Chem Biol. 2022 07 15; 17(7):1756-1768.

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