 Antithrombins
"Antithrombins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Endogenous factors and drugs that directly inhibit the action of THROMBIN, usually by blocking its enzymatic activity. They are distinguished from INDIRECT THROMBIN INHIBITORS, such as HEPARIN, which act by enhancing the inhibitory effects of antithrombins.
| Descriptor ID |
D000991
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| MeSH Number(s) |
D27.505.519.389.745.800.449 D27.505.954.502.119.500
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| Concept/Terms |
Antithrombins- Antithrombins
- Direct Thrombin Inhibitors
- Thrombin Inhibitors, Direct
- Direct Antithrombins
- Antithrombins, Direct
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Below are MeSH descriptors whose meaning is more general than "Antithrombins".
Below are MeSH descriptors whose meaning is more specific than "Antithrombins".
This graph shows the total number of publications written about "Antithrombins" by people in this website by year, and whether "Antithrombins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 | | 2010 | 1 | 0 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Antithrombins" by people in Profiles.
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Schulman S, Carrier M, Lee AY, Shivakumar S, Blostein M, Spencer FA, Solymoss S, Barty R, Wang G, Heddle N, Douketis JD. Perioperative Management of Dabigatran: A Prospective Cohort Study. Circulation. 2015 Jul 21; 132(3):167-73.
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Sylvia LM, Ordway L, Pham DT, DeNofrio D, Kiernan M. Bivalirudin for treatment of LVAD thrombosis: a case series. ASAIO J. 2014 Nov-Dec; 60(6):744-7.
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Ross B, Miller MA, Ditch K, Tran M. Clinical experience of life-threatening dabigatran-related bleeding at a large, tertiary care, academic medical center: a case series. J Med Toxicol. 2014 Jun; 10(2):223-8.
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Blum J, Carreiro S, Hack JB. Intravenous lipid emulsion does not reverse dabigatran-induced anticoagulation in a rat model. Acad Emerg Med. 2013 Oct; 20(10):1022-5.
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Maan A, Padmanabhan R, Shaikh AY, Mansour M, Ruskin JN, Heist EK. Newer anticoagulants in cardiovascular disease: a systematic review of the literature. Cardiol Rev. 2012 Sep-Oct; 20(5):209-21.
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Loke C, Ali SS, Johari V. Pharmacology of anticoagulants. Dis Mon. 2012 Aug; 58(8):424-30.
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Ganetsky M, Babu KM, Salhanick SD, Brown RS, Boyer EW. Dabigatran: review of pharmacology and management of bleeding complications of this novel oral anticoagulant. J Med Toxicol. 2011 Dec; 7(4):281-7.
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Donovan JL, Tran MT, Kanaan AO. An overview of heparin-induced thrombocytopenia. J Pharm Pract. 2010 Jun; 23(3):226-34.
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Tran M, Spencer FA. Thromboepidemiology: identifying patients with heritable risk for thrombin-mediated thromboembolic events. Am Heart J. 2005 Jan; 149(1 Suppl):S9-18.
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Hartman CA, Faria CE, Mago K. Visual compatibility of bivalirudin with selected drugs. Am J Health Syst Pharm. 2004 Sep 1; 61(17):1774, 1776.
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