 Insulin-Like Growth Factor I
"Insulin-Like Growth Factor I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.
| Descriptor ID |
D007334
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| MeSH Number(s) |
D12.644.276.937.400 D12.776.124.862.400 D12.776.467.937.400 D23.529.937.400
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| Concept/Terms |
Insulin-Like Growth Factor I- Insulin-Like Growth Factor I
- Insulin-Like Somatomedin Peptide I
- Insulin Like Somatomedin Peptide I
- Somatomedin C
- IGF-I-SmC
- IGF-1
- IGF-I
- Insulin Like Growth Factor I
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Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor I".
Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor I".
This graph shows the total number of publications written about "Insulin-Like Growth Factor I" by people in this website by year, and whether "Insulin-Like Growth Factor I" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1981 | 0 | 1 | 1 | | 1989 | 1 | 0 | 1 | | 1991 | 0 | 2 | 2 | | 1992 | 1 | 1 | 2 | | 1993 | 0 | 1 | 1 | | 1994 | 3 | 2 | 5 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 1 | 2 | | 2000 | 1 | 1 | 2 | | 2001 | 2 | 3 | 5 | | 2003 | 3 | 2 | 5 | | 2004 | 1 | 5 | 6 | | 2005 | 2 | 2 | 4 | | 2006 | 2 | 3 | 5 | | 2007 | 0 | 1 | 1 | | 2008 | 2 | 3 | 5 | | 2009 | 2 | 2 | 4 | | 2010 | 1 | 2 | 3 | | 2011 | 3 | 1 | 4 | | 2012 | 1 | 1 | 2 | | 2013 | 3 | 0 | 3 | | 2014 | 2 | 1 | 3 | | 2015 | 1 | 2 | 3 | | 2016 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Insulin-Like Growth Factor I" by people in Profiles.
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Nuutila K, Sakthivel D, Kruse C, Tran P, Giatsidis G, Sinha I. Gene expression profiling of skeletal muscle after volumetric muscle loss. Wound Repair Regen. 2017 05; 25(3):408-413.
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Riedl I, Osler ME, Björnholm M, Egan B, Nader GA, Chibalin AV, Zierath JR. AMPK?3 is dispensable for skeletal muscle hypertrophy induced by functional overload. Am J Physiol Endocrinol Metab. 2016 Mar 15; 310(6):E461-72.
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Srinivasa S, Suresh C, Mottla J, Hamarneh SR, Irazoqui JE, Frontera W, Torriani M, Stanley T, Makimura H. FNDC5 relates to skeletal muscle IGF-I and mitochondrial function and gene expression in obese men with reduced growth hormone. Growth Horm IGF Res. 2016 Feb; 26:36-41.
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Rojas-Rodriguez R, Lifshitz LM, Bellve KD, Min SY, Pires J, Leung K, Boeras C, Sert A, Draper JT, Corvera S, Moore Simas TA. Human adipose tissue expansion in pregnancy is impaired in gestational diabetes mellitus. Diabetologia. 2015 Sep; 58(9):2106-14.
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Rohatgi RA, Janusis J, Leonard D, Bellvé KD, Fogarty KE, Baehrecke EH, Corvera S, Shaw LM. Beclin 1 regulates growth factor receptor signaling in breast cancer. Oncogene. 2015 Oct 16; 34(42):5352-62.
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Hamarneh SR, Murphy CA, Shih CW, Frontera W, Torriani M, Irazoqui JE, Makimura H. Relationship between serum IGF-1 and skeletal muscle IGF-1 mRNA expression to phosphocreatine recovery after exercise in obese men with reduced GH. J Clin Endocrinol Metab. 2015 Feb; 100(2):617-25.
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Gealekman O, Gurav K, Chouinard M, Straubhaar J, Thompson M, Malkani S, Hartigan C, Corvera S. Control of adipose tissue expandability in response to high fat diet by the insulin-like growth factor-binding protein-4. J Biol Chem. 2014 Jun 27; 289(26):18327-38.
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Byrne AB, Walradt T, Gardner KE, Hubbert A, Reinke V, Hammarlund M. Insulin/IGF1 signaling inhibits age-dependent axon regeneration. Neuron. 2014 Feb 05; 81(3):561-73.
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Yamauchi J, Kumar A, Duarte L, Mehuron T, Girgenrath M. Triggering regeneration and tackling apoptosis: a combinatorial approach to treating congenital muscular dystrophy type 1 A. Hum Mol Genet. 2013 Nov 1; 22(21):4306-17.
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Neacsu O, Cleveland K, Xu H, Tchkonia TT, Kirkland JL, Boney CM. IGF-I attenuates FFA-induced activation of JNK1 phosphorylation and TNFa expression in human subcutaneous preadipocytes. Obesity (Silver Spring). 2013 Sep; 21(9):1843-9.
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