Insulin-Like Growth Factor II

"Insulin-Like Growth Factor II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A well-characterized neutral peptide believed to be secreted by the LIVER and to circulate in the BLOOD. It has growth-regulating, insulin-like and mitogenic activities. The growth factor has a major, but not absolute, dependence on SOMATOTROPIN. It is believed to be a major fetal growth factor in contrast to INSULIN-LIKE GROWTH FACTOR I, which is a major growth factor in adults.

Descriptor ID	D007335
MeSH Number(s)	D12.644.276.937.420 D12.776.124.862.425 D12.776.467.937.420 D23.529.937.420
Concept/Terms	Insulin-Like Growth Factor II Insulin-Like Growth Factor II IGF-II Insulin Like Growth Factor II Insulin-Like Somatomedin Peptide II Insulin Like Somatomedin Peptide II Multiplication-Stimulating Factor Factor, Multiplication-Stimulating Multiplication Stimulating Factor Somatomedin A Somatomedin MSA IGF-2 Multiplication-Stimulating Activity Multiplication Stimulating Activity

Below are MeSH descriptors whose meaning is more general than "Insulin-Like Growth Factor II".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Somatomedins [D12.644.276.937]
Insulin-Like Growth Factor II [D12.644.276.937.420]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Somatomedins [D12.776.124.862]
Insulin-Like Growth Factor II [D12.776.124.862.425]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Somatomedins [D12.776.467.937]
Insulin-Like Growth Factor II [D12.776.467.937.420]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Somatomedins [D23.529.937]
Insulin-Like Growth Factor II [D23.529.937.420]

Below are MeSH descriptors whose meaning is related to "Insulin-Like Growth Factor II".

Below are MeSH descriptors whose meaning is more specific than "Insulin-Like Growth Factor II".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Insulin-Like Growth Factor II" by people in this website by year, and whether "Insulin-Like Growth Factor II" was a major or minor topic of these publications.

Bar chart showing 17 publications over 14 distinct years, with a maximum of 2 publications in 2014 and 2015 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	1	0	1
2005	0	1	1
2006	1	0	1
2007	0	1	1
2008	0	1	1
2009	0	1	1
2010	0	1	1
2013	1	0	1
2014	2	0	2
2015	0	2	2
2017	0	1	1
2018	1	1	2
2021	1	0	1
2024	1	0	1

Below are the most recent publications written about "Insulin-Like Growth Factor II" by people in Profiles.

Cannarella R, Rando OJ, Condorelli RA, Chamayou S, Romano S, Guglielmino A, Yin Q, Hans TG, Mancuso F, Arato I, Bellucci C, Luca G, Lundy SD, La Vignera S, Calogero AE. Sperm-carried IGF2: towards the discovery of a spark contributing to embryo growth and development. Mol Hum Reprod. 2024 Sep 12; 30(9).

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Lero MW, Shaw LM. Diversity of insulin and IGF signaling in breast cancer: Implications for therapy. Mol Cell Endocrinol. 2021 05 01; 527:111213.

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Bryzgalov DV, Kuznetsova IL, Rogaev EI. Enhancement of Declarative Memory: From Genetic Regulation to Non-invasive Stimulation. Biochemistry (Mosc). 2018 Sep; 83(9):1124-1138.

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Younis S, Sch?nke M, Massart J, Hjortebjerg R, Sundstr?m E, Gustafson U, Bj?rnholm M, Krook A, Frystyk J, Zierath JR, Andersson L. The ZBED6-IGF2 axis has a major effect on growth of skeletal muscle and internal organs in placental mammals. Proc Natl Acad Sci U S A. 2018 02 27; 115(9):E2048-E2057.

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Xu R, Zhang C, Shin DY, Kim JM, Lalani S, Li N, Yang YS, Liu Y, Eiseman M, Davis RJ, Shim JH, Greenblatt MB. c-Jun N-Terminal Kinases (JNKs) Are Critical Mediators of Osteoblast Activity In Vivo. J Bone Miner Res. 2017 Sep; 32(9):1811-1815.

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Switkowski KM, Jacques PF, Must A, Hivert MF, Fleisch A, Gillman MW, Rifas-Shiman S, Oken E. Higher Maternal Protein Intake during Pregnancy Is Associated with Lower Cord Blood Concentrations of Insulin-like Growth Factor (IGF)-II, IGF Binding Protein 3, and Insulin, but Not IGF-I, in a Cohort of Women with High Protein Intake. J Nutr. 2017 07; 147(7):1392-1400.

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Rojas-Rodriguez R, Lifshitz LM, Bellve KD, Min SY, Pires J, Leung K, Boeras C, Sert A, Draper JT, Corvera S, Moore Simas TA. Human adipose tissue expansion in pregnancy is impaired in gestational diabetes mellitus. Diabetologia. 2015 Sep; 58(9):2106-14.

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Moore GE, Ishida M, Demetriou C, Al-Olabi L, Leon LJ, Thomas AC, Abu-Amero S, Frost JM, Stafford JL, Chaoqun Y, Duncan AJ, Baigel R, Brimioulle M, Iglesias-Platas I, Apostolidou S, Aggarwal R, Whittaker JC, Syngelaki A, Nicolaides KH, Regan L, Monk D, Stanier P. The role and interaction of imprinted genes in human fetal growth. Philos Trans R Soc Lond B Biol Sci. 2015 Mar 05; 370(1663):20140074.

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Demetriou C, Abu-Amero S, Thomas AC, Ishida M, Aggarwal R, Al-Olabi L, Leon LJ, Stafford JL, Syngelaki A, Peebles D, Nicolaides KH, Regan L, Stanier P, Moore GE. Paternally expressed, imprinted insulin-like growth factor-2 in chorionic villi correlates significantly with birth weight. PLoS One. 2014; 9(1):e85454.

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Reyes-Gutierrez P, Ritland Politz JC, Pederson T. A mRNA and cognate microRNAs localize in the nucleolus. Nucleus. 2014; 5(6):636-42.

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