"Diacylglycerol Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme of the transferase class that uses ATP to catalyze the phosphorylation of diacylglycerol to a phosphatidate. EC 2.7.1.107.
| Descriptor ID |
D019852
|
| MeSH Number(s) |
D08.811.913.696.620.200
|
| Concept/Terms |
Diacylglycerol Kinase- Diacylglycerol Kinase
- Kinase, Diacylglycerol
- 1,2-Diacylglycerol Kinase
- 1,2 Diacylglycerol Kinase
- Kinase, 1,2-Diacylglycerol
- DAG Kinase
- Kinase, DAG
- Diglyceride Kinase
- Kinase, Diglyceride
|
Below are MeSH descriptors whose meaning is more general than "Diacylglycerol Kinase".
Below are MeSH descriptors whose meaning is more specific than "Diacylglycerol Kinase".
This graph shows the total number of publications written about "Diacylglycerol Kinase" by people in this website by year, and whether "Diacylglycerol Kinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 3 | 0 | 3 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Diacylglycerol Kinase" by people in Profiles.
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Massart J, Zierath JR. Role of Diacylglycerol Kinases in Glucose and Energy Homeostasis. Trends Endocrinol Metab. 2019 09; 30(9):603-617.
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Nascimento EBM, Manner?s-Holm L, Chibalin AV, Bj?rnholm M, Zierath JR. Diacylglycerol kinase a deficiency alters inflammation markers in adipose tissue in response to a high-fat diet. J Lipid Res. 2018 02; 59(2):273-282.
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Benziane B, Borg ML, Tom RZ, Riedl I, Massart J, Bj?rnholm M, Gilbert M, Chibalin AV, Zierath JR. DGK? deficiency protects against peripheral insulin resistance and improves energy metabolism. J Lipid Res. 2017 12; 58(12):2324-2333.
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Manner?s-Holm L, Sch?nke M, Brozinick JT, Vetterli L, Bui HH, Sanders P, Nascimento EBM, Bj?rnholm M, Chibalin AV, Zierath JR. Diacylglycerol kinase e deficiency preserves glucose tolerance and modulates lipid metabolism in obese mice. J Lipid Res. 2017 05; 58(5):907-915.
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Jiang LQ, de Castro Barbosa T, Massart J, Deshmukh AS, L?fgren L, Duque-Guimaraes DE, Ozilgen A, Osler ME, Chibalin AV, Zierath JR. Diacylglycerol kinase-d regulates AMPK signaling, lipid metabolism, and skeletal muscle energetics. Am J Physiol Endocrinol Metab. 2016 Jan 01; 310(1):E51-60.
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Dorrell C, Grompe MT, Pan FC, Zhong Y, Canaday PS, Shultz LD, Greiner DL, Wright CV, Streeter PR, Grompe M. Isolation of mouse pancreatic alpha, beta, duct and acinar populations with cell surface markers. Mol Cell Endocrinol. 2011 Jun 06; 339(1-2):144-50.
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Chibalin AV, Leng Y, Vieira E, Krook A, Bj?rnholm M, Long YC, Kotova O, Zhong Z, Sakane F, Steiler T, Nyl?n C, Wang J, Laakso M, Topham MK, Gilbert M, Wallberg-Henriksson H, Zierath JR. Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance. Cell. 2008 Feb 08; 132(3):375-86.
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Fritz T, Kr?mer DK, Karlsson HK, Galuska D, Engfeldt P, Zierath JR, Krook A. Low-intensity exercise increases skeletal muscle protein expression of PPARdelta and UCP3 in type 2 diabetic patients. Diabetes Metab Res Rev. 2006 Nov-Dec; 22(6):492-8.