"Cyclosporins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.
| Descriptor ID |
D003524
|
| MeSH Number(s) |
D04.345.566.235 D12.644.641.235
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cyclosporins".
Below are MeSH descriptors whose meaning is more specific than "Cyclosporins".
This graph shows the total number of publications written about "Cyclosporins" by people in this website by year, and whether "Cyclosporins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclosporins" by people in Profiles.
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Franke EK, Luban J. Inhibition of HIV-1 replication by cyclosporine A or related compounds correlates with the ability to disrupt the Gag-cyclophilin A interaction. Virology. 1996 Aug 01; 222(1):279-82.
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Franke EK, Luban J. Cyclophilin and gag in HIV-1 replication and pathogenesis. Adv Exp Med Biol. 1995; 374:217-28.
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Kniha H, Randzio J, Gold ME, Fudem GM, Cruz HG, Park HH, Furnas DW. Growth of forelimb allografts in young rabbits immunosuppressed with cyclosporine. Ann Plast Surg. 1989 Feb; 22(2):135-41.
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Danielson PE, Forss-Petter S, Brow MA, Calavetta L, Douglass J, Milner RJ, Sutcliffe JG. p1B15: a cDNA clone of the rat mRNA encoding cyclophilin. DNA. 1988 May; 7(4):261-7.
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Kakizaki K, Didlake R, Basadonna G, Kahan BD, Merrell RC. Donor-specific antigen and cyclosporine in rat islet allografts. J Surg Res. 1987 May; 42(5):494-7.
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Kakizaki K, Basadonna G, Merrell RC. Allotransplantation of islet endocrine aggregates. Diabetes. 1987 Mar; 36(3):315-9.
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Basadonna G, Kakizaki K, Merrell RC. Effect of cyclosporine on established islet autografts. J Surg Res. 1986 May; 40(5):450-4.
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Brovall C, Levitz SM, Ellner JJ, Schacter B. Radioresistance of culture-induced augmented natural killer-like activity. Hum Immunol. 1983 Jul; 7(3):151-62.