"Cyclosporins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.
| Descriptor ID |
D003524
|
| MeSH Number(s) |
D04.345.566.235 D12.644.641.235
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cyclosporins".
Below are MeSH descriptors whose meaning is more specific than "Cyclosporins".
This graph shows the total number of publications written about "Cyclosporins" by people in this website by year, and whether "Cyclosporins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 |
| 1996 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclosporins" by people in Profiles.
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Franke EK, Luban J. Inhibition of HIV-1 replication by cyclosporine A or related compounds correlates with the ability to disrupt the Gag-cyclophilin A interaction. Virology. 1996 Aug 01; 222(1):279-82.
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Franke EK, Luban J. Cyclophilin and gag in HIV-1 replication and pathogenesis. Adv Exp Med Biol. 1995; 374:217-28.
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Shaw LM, Yatscoff RW, Bowers LD, Freeman DJ, Jeffery JR, Keown PA, McGilveray IJ, Rosano TG, Wong PY. Canadian Consensus Meeting on cyclosporine monitoring: report of the consensus panel. Clin Chem. 1990 Oct; 36(10):1841-6.
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Kahan BD, Shaw LM, Holt D, Grevel J, Johnston A. Consensus document: Hawk's Cay meeting on therapeutic drug monitoring of cyclosporine. Clin Chem. 1990 Aug; 36(8 Pt 1):1510-6.
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Shaw LM, Audet PR, Grossman RA, Fields L, Lensmeyer GL, Dafoe DC. Adjustment of cyclosporine dosage in renal transplant patients based on concentration measured specifically in whole blood: clinical outcome results and diagnostic utility. Transplant Proc. 1990 Jun; 22(3):1267-73.
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Cooney GF, Fiel SB, Shaw LM, Cavarocchi NC. Cyclosporine bioavailability in heart-lung transplant candidates with cystic fibrosis. Transplantation. 1990 Apr; 49(4):821-3.
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Shaw LM. Cyclosporine metabolites: are they active? Clin Chem. 1990 Feb; 36(2):187.
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Shaw LM. Advances in cyclosporine pharmacology, measurement, and therapeutic monitoring. Clin Chem. 1989 Jul; 35(7):1299-308.
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Kniha H, Randzio J, Gold ME, Fudem GM, Cruz HG, Park HH, Furnas DW. Growth of forelimb allografts in young rabbits immunosuppressed with cyclosporine. Ann Plast Surg. 1989 Feb; 22(2):135-41.
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Shaw LM. Cyclosporine monitoring. Clin Chem. 1989 Jan; 35(1):5-6.