Epitopes, T-Lymphocyte

"Epitopes, T-Lymphocyte" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Antigenic determinants recognized and bound by the T-cell receptor. Epitopes recognized by the T-cell receptor are often located in the inner, unexposed side of the antigen, and become accessible to the T-cell receptors after proteolytic processing of the antigen.

Descriptor ID	D018984
MeSH Number(s)	D23.050.550.402
Concept/Terms	Epitopes, T-Lymphocyte Epitopes, T-Lymphocyte Epitopes, T Lymphocyte T-Cell Epitopes Epitopes, T-Cell T Cell Epitopes T-Lymphocyte Epitopes T Lymphocyte Epitopes T-Cell Epitope Epitope, T-Cell T Cell Epitope T-Lymphocyte Epitope Epitope, T-Lymphocyte T Lymphocyte Epitope

Below are MeSH descriptors whose meaning is more general than "Epitopes, T-Lymphocyte".

Chemicals and Drugs [D]
Biological Factors [D23]
Antigens [D23.050]
Epitopes [D23.050.550]
Epitopes, T-Lymphocyte [D23.050.550.402]

Below are MeSH descriptors whose meaning is related to "Epitopes, T-Lymphocyte".

Below are MeSH descriptors whose meaning is more specific than "Epitopes, T-Lymphocyte".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Epitopes, T-Lymphocyte" by people in this website by year, and whether "Epitopes, T-Lymphocyte" was a major or minor topic of these publications.

Bar chart showing 137 publications over 27 distinct years, with a maximum of 11 publications in 2002 and 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	1	0	1
1999	4	2	6
2000	0	2	2
2001	2	2	4
2002	8	3	11
2003	2	3	5
2004	2	4	6
2005	4	4	8
2006	5	6	11
2007	4	1	5
2008	4	6	10
2009	2	1	3
2010	2	7	9
2011	0	4	4
2012	4	2	6
2013	5	5	10
2014	4	2	6
2015	0	2	2
2017	2	3	5
2018	3	2	5
2019	2	2	4
2020	2	3	5
2022	0	1	1
2023	0	2	2
2024	1	0	1
2025	1	1	2
2026	2	1	3

Below are the most recent publications written about "Epitopes, T-Lymphocyte" by people in Profiles.

Costa CM, Almeida GG, Lindestam Arlehamn CS, Queiroz-Glauss CP, Gunderman VHG, Pereira MMM, Amaral LRD, Pereira DB, Tada MS, Martins-Filho OA, Gazzinelli RT, Antonelli LRDV. Different clinical forms of Plasmodium vivax infection result in unique T cell epitope-specific immune responses. J Immunol. 2026 Apr 15; 215(4).

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Amdare N, Ali R, Manganaro A, Baker JC, Antal Z, Smith C, Santamaria P, Kent SC, DiLorenzo TP. Islet-derived T cells from both mice and humans recognize conserved insulin A-chain peptides presented by HLA-C*03:04. J Immunol. 2026 Feb 09; 215(2).

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Ramesh KM, Lu L, Stern LJ. T Cell Assay to Track Presentation of an Influenza Hemagglutinin Epitope Presented by the MHC-II Protein HLA-DR1. Methods Mol Biol. 2026; 3007:255-273.

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Becerra-Artiles A, Weaver GC, Oluoch PO, Stern LJ. TCR repertoire of human cytotoxic CD4 T cells responding to betaherpesviruses HHV-6B and HCMV. Front Immunol. 2025; 16:1631558.

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Murata K, Minowa T, Tsukahara T, Yoshida T, Minami A, Nakatsugawa M, Mizue Y, Murai A, Tokita S, Sasaki K, Uhara H, Kubo T, Kanaseki T, Torigoe T, Hirohashi Y. An SNP-dependent cancer-testis antigenic epitope serves as a promising immunotherapeutic target for cancer. Oncoimmunology. 2025 Dec; 14(1):2528110.

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Croce G, Lani R, Tardivon D, Bobisse S, de Tiani M, Bragina M, Perez MAS, Michaux J, Pak HS, Michel A, Gehret T, Schmidt J, Guillame P, Bassani-Sternberg M, Zoete V, Harari A, Rufer N, Hebeisen M, Dunn SM, Gfeller D. Phage display enables machine learning discovery of cancer antigen-specific TCRs. Sci Adv. 2025 Jun 13; 11(24):eads5589.

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Amdare NP, Shultz LD, Greiner DL, DiLorenzo TP. Human insulin as both antigen and protector in type 1 diabetes. Eur J Immunol. 2024 09; 54(9):e2350949.

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Becerra-Artiles A, Nanaware PP, Muneeruddin K, Weaver GC, Shaffer SA, Calvo-Calle JM, Stern LJ. Immunopeptidome profiling of human coronavirus OC43-infected cells identifies CD4 T-cell epitopes specific to seasonal coronaviruses or cross-reactive with SARS-CoV-2. PLoS Pathog. 2023 07; 19(7):e1011032.

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Guyer P, Arribas-Layton D, Manganaro A, Speake C, Lord S, Eizirik DL, Kent SC, Mallone R, James EA. Recognition of mRNA Splice Variant and Secretory Granule Epitopes by CD4+ T Cells in Type 1 Diabetes. Diabetes. 2023 01 01; 72(1):85-96.

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Becerra-Artiles A, Calvo-Calle JM, Co MD, Nanaware PP, Cruz J, Weaver GC, Lu L, Forconi C, Finberg RW, Moormann AM, Stern LJ. Broadly recognized, cross-reactive SARS-CoV-2 CD4 T cell epitopes are highly conserved across human coronaviruses and presented by common HLA alleles. Cell Rep. 2022 06 14; 39(11):110952.

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