Peptide Chain Termination, Translational
"Peptide Chain Termination, Translational" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A process of GENETIC TRANSLATION whereby the terminal amino acid is added to a lengthening polypeptide. This termination process is signaled from the MESSENGER RNA, by one of three termination codons (CODON, TERMINATOR) that immediately follows the last amino acid-specifying CODON.
| Descriptor ID |
D010443
|
| MeSH Number(s) |
G02.111.660.871.720 G03.734.871.720
|
| Concept/Terms |
Peptide Chain Termination, Translational- Peptide Chain Termination, Translational
- Chain Termination, Peptide, Translational
- Protein Chain Termination, Translational
- Protein Translation Termination
- Translational Termination, Protein
- Protein Translational Termination
- Termination, Protein Translational
- Translation Termination, Genetic
- Genetic Translation Termination
- Termination, Genetic Translation
- Protein Biosynthesis Termination
- Biosynthesis Termination, Protein
- Termination, Protein Biosynthesis
- Translational Peptide Chain Termination
- Translation Termination, Protein
- Termination, Protein Translation
|
Below are MeSH descriptors whose meaning is more general than "Peptide Chain Termination, Translational".
Below are MeSH descriptors whose meaning is more specific than "Peptide Chain Termination, Translational".
This graph shows the total number of publications written about "Peptide Chain Termination, Translational" by people in this website by year, and whether "Peptide Chain Termination, Translational" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 2 | 3 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Peptide Chain Termination, Translational" by people in Profiles.
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Korostelev AA. Diversity and Similarity of Termination and Ribosome Rescue in Bacterial, Mitochondrial, and Cytoplasmic Translation. Biochemistry (Mosc). 2021 Sep; 86(9):1107-1121.
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Mangkalaphiban K, He F, Ganesan R, Wu C, Baker R, Jacobson A. Transcriptome-wide investigation of stop codon readthrough in Saccharomyces cerevisiae. PLoS Genet. 2021 04; 17(4):e1009538.
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Wu C, Roy B, He F, Yan K, Jacobson A. Poly(A)-Binding Protein Regulates the Efficiency of Translation Termination. Cell Rep. 2020 11 17; 33(7):108399.
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Susorov D, Egri S, Korostelev AA. Termi-Luc: a versatile assay to monitor full-protein release from ribosomes. RNA. 2020 12; 26(12):2044-2050.
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Svidritskiy E, Demo G, Loveland AB, Xu C, Korostelev AA. Extensive ribosome and RF2 rearrangements during translation termination. Elife. 2019 09 12; 8.
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Svidritskiy E, Demo G, Korostelev AA. Mechanism of premature translation termination on a sense codon. J Biol Chem. 2018 08 10; 293(32):12472-12479.
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Svidritskiy E, Korostelev AA. Conformational Control of Translation Termination on the 70S Ribosome. Structure. 2018 06 05; 26(6):821-828.e3.
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Svidritskiy E, Korostelev AA. Mechanism of Inhibition of Translation Termination by Blasticidin S. J Mol Biol. 2018 03 02; 430(5):591-593.
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Svidritskiy E, Madireddy R, Korostelev AA. Structural Basis for Translation Termination on a Pseudouridylated Stop Codon. J Mol Biol. 2016 05 22; 428(10 Pt B):2228-36.
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He F, Jacobson A. Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story. Annu Rev Genet. 2015; 49:339-66.