"Ketoglutaric Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of compounds containing an oxo group with the general structure of 1,5-pentanedioic acid. (From Lehninger, Principles of Biochemistry, 1982, p442)
Descriptor ID |
D007656
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MeSH Number(s) |
D02.241.081.337.351.502 D02.241.755.465
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Ketoglutaric Acids".
Below are MeSH descriptors whose meaning is more specific than "Ketoglutaric Acids".
This graph shows the total number of publications written about "Ketoglutaric Acids" by people in this website by year, and whether "Ketoglutaric Acids" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1998 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2011 | 0 | 2 | 2 |
2015 | 1 | 0 | 1 |
2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ketoglutaric Acids" by people in Profiles.
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Anderson NM, Li D, Peng HL, Laroche FJ, Mansour MR, Gjini E, Aioub M, Helman DJ, Roderick JE, Cheng T, Harrold I, Samaha Y, Meng L, Amsterdam A, Neuberg DS, Denton TT, Sanda T, Kelliher MA, Singh A, Look AT, Feng H. The TCA cycle transferase DLST is important for MYC-mediated leukemogenesis. Leukemia. 2016 06; 30(6):1365-74.
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Wang L, Hou Y, Yi D, Li Y, Ding B, Zhu H, Liu J, Xiao H, Wu G. Dietary supplementation with glutamate precursor ?-ketoglutarate attenuates lipopolysaccharide-induced liver injury in young pigs. Amino Acids. 2015 Jul; 47(7):1309-18.
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Possemato R, Marks KM, Shaul YD, Pacold ME, Kim D, Birsoy K, Sethumadhavan S, Woo HK, Jang HG, Jha AK, Chen WW, Barrett FG, Stransky N, Tsun ZY, Cowley GS, Barretina J, Kalaany NY, Hsu PP, Ottina K, Chan AM, Yuan B, Garraway LA, Root DE, Mino-Kenudson M, Brachtel EF, Driggers EM, Sabatini DM. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer. Nature. 2011 Aug 18; 476(7360):346-50.
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Giri NC, Sun H, Chen H, Costa M, Maroney MJ. X-ray absorption spectroscopy structural investigation of early intermediates in the mechanism of DNA repair by human ABH2. Biochemistry. 2011 Jun 07; 50(22):5067-76.
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Kelley RI, Robinson D, Puffenberger EG, Strauss KA, Morton DH. Amish lethal microcephaly: a new metabolic disorder with severe congenital microcephaly and 2-ketoglutaric aciduria. Am J Med Genet. 2002 Nov 01; 112(4):318-26.
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Cho H, Adrio JL, Luengo JM, Wolfe S, Ocran S, Hintermann G, Piret JM, Demain AL. Elucidation of conditions allowing conversion of penicillin G and other penicillins to deacetoxycephalosporins by resting cells and extracts of Streptomyces clavuligerus NP1. Proc Natl Acad Sci U S A. 1998 Sep 29; 95(20):11544-8.