"Muscarine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A toxic alkaloid found in Amanita muscaria (fly fungus) and other fungi of the Inocybe species. It is the first parasympathomimetic substance ever studied and causes profound parasympathetic activation that may end in convulsions and death. The specific antidote is atropine.
| Descriptor ID |
D009116
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| MeSH Number(s) |
D02.092.877.883.777 D02.675.276.580 D03.132.545
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Muscarine".
Below are MeSH descriptors whose meaning is more specific than "Muscarine".
This graph shows the total number of publications written about "Muscarine" by people in this website by year, and whether "Muscarine" was a major or minor topic of these publications.
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Below are the most recent publications written about "Muscarine" by people in Profiles.
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Sims SM, Clapp LH, Walsh JV, Singer JJ. Dual regulation of M current in gastric smooth muscle cells: beta-adrenergic-muscarinic antagonism. Pflugers Arch. 1990 Nov; 417(3):291-302.
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Sims SM, Vivaudou MB, Hillemeier C, Biancani P, Walsh JV, Singer JJ. Membrane currents and cholinergic regulation of K+ current in esophageal smooth muscle cells. Am J Physiol. 1990 May; 258(5 Pt 1):G794-802.
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Sims SM, Singer JJ, Walsh JV. Antagonistic adrenergic-muscarinic regulation of M current in smooth muscle cells. Science. 1988 Jan 08; 239(4836):190-3.
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Clapp LH, Vivaudou MB, Walsh JV, Singer JJ. Acetylcholine increases voltage-activated Ca2+ current in freshly dissociated smooth muscle cells. Proc Natl Acad Sci U S A. 1987 Apr; 84(7):2092-6.
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Sims SM, Singer JJ, Walsh JV. Cholinergic agonists suppress a potassium current in freshly dissociated smooth muscle cells of the toad. J Physiol. 1985 Oct; 367:503-29.