Ion Channel Gating

"Ion Channel Gating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The opening and closing of ion channels due to a stimulus. The stimulus can be a change in membrane potential (voltage-gated), drugs or chemical transmitters (ligand-gated), or a mechanical deformation. Gating is thought to involve conformational changes of the ion channel which alters selective permeability.

Descriptor ID	D015640
MeSH Number(s)	G02.111.820.400 G04.835.400 G07.265.625
Concept/Terms	Ion Channel Gating Ion Channel Gating Gating, Ion Channel Gatings, Ion Channel Ion Channel Gatings

Below are MeSH descriptors whose meaning is more general than "Ion Channel Gating".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Signal Transduction [G02.111.820]
Ion Channel Gating [G02.111.820.400]
Cell Physiological Phenomena [G04]
Signal Transduction [G04.835]
Ion Channel Gating [G04.835.400]
Physiological Phenomena [G07]
Electrophysiological Phenomena [G07.265]
Ion Channel Gating [G07.265.625]

Below are MeSH descriptors whose meaning is more specific than "Ion Channel Gating".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ion Channel Gating" by people in this website by year, and whether "Ion Channel Gating" was a major or minor topic of these publications.

Bar chart showing 36 publications over 21 distinct years, with a maximum of 4 publications in 2004

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	0	1	1
1997	1	1	2
1999	1	1	2
2000	0	2	2
2001	1	0	1
2002	1	0	1
2004	1	3	4
2005	0	1	1
2006	0	1	1
2007	1	1	2
2008	2	1	3
2009	1	2	3
2010	1	0	1
2011	1	0	1
2014	1	1	2
2015	1	1	2
2016	0	1	1
2017	0	1	1
2018	3	0	3
2019	1	0	1
2021	0	1	1

Below are the most recent publications written about "Ion Channel Gating" by people in Profiles.

Rish AD, Shen Z, Fu TM. It takes two to Tango: Two gates orchestrate the opening of human TRPM2. Cell Calcium. 2022 01; 101:102523.

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Xia S, Wang L, Fu TM, Wu H. Mechanism of TRPM2 channel gating revealed by cryo-EM. FEBS J. 2019 09; 286(17):3333-3339.

View in: PubMed
Wang L, Fu TM, Zhou Y, Xia S, Greka A, Wu H. Structures and gating mechanism of human TRPM2. Science. 2018 12 21; 362(6421).

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Zhu L, Cui Q, Xiao H, Liao X, Chen X. Gating and inactivation of mechanosensitive channels of small conductance: A continuum mechanics study. J Mech Behav Biomed Mater. 2019 02; 90:502-514.

View in: PubMed
Macri V, Brody JA, Arking DE, Hucker WJ, Yin X, Lin H, Mills RW, Sinner MF, Lubitz SA, Liu CT, Morrison AC, Alonso A, Li N, Fedorov VV, Janssen PM, Bis JC, Heckbert SR, Dolmatova EV, Lumley T, Sitlani CM, Cupples LA, Pulit SL, Newton-Cheh C, Barnard J, Smith JD, Van Wagoner DR, Chung MK, Vlahakes GJ, O'Donnell CJ, Rotter JI, Margulies KB, Morley MP, Cappola TP, Benjamin EJ, Muzny D, Gibbs RA, Jackson RD, Magnani JW, Herndon CN, Rich SS, Psaty BM, Milan DJ, Boerwinkle E, Mohler PJ, Sotoodehnia N, Ellinor PT. Common Coding Variants in SCN10A Are Associated With the Nav1.8 Late Current and Cardiac Conduction. Circ Genom Precis Med. 2018 05; 11(5):e001663.

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Hasegawa Y, Mao W, Saha S, Gunner G, Kolpakova J, Martin GE, Futai K. Luciferase shRNA Presents off-Target Effects on Voltage-Gated Ion Channels in Mouse Hippocampal Pyramidal Neurons. eNeuro. 2017 Sep-Oct; 4(5).

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Tajima N, Karakas E, Grant T, Simorowski N, Diaz-Avalos R, Grigorieff N, Furukawa H. Activation of NMDA receptors and the mechanism of inhibition by ifenprodil. Nature. 2016 06 02; 534(7605):63-8.

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Croisier H, Tan X, Chen J, Sneyd J, Sanderson MJ, Brook BS. Ryanodine receptor sensitization results in abnormal calcium signaling in airway smooth muscle cells. Am J Respir Cell Mol Biol. 2015 Nov; 53(5):703-11.

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Escoffier J, Navarrete F, Haddad D, Santi CM, Darszon A, Visconti PE. Flow cytometry analysis reveals that only a subpopulation of mouse sperm undergoes hyperpolarization during capacitation. Biol Reprod. 2015 May; 92(5):121.

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Mruk K, Kobertz WR. Bioreactive Tethers. Adv Exp Med Biol. 2015; 869:77-100.

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