Mechanotransduction, Cellular

"Mechanotransduction, Cellular" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The process by which cells convert mechanical stimuli into a chemical response. It can occur in both cells specialized for sensing mechanical cues such as MECHANORECEPTORS, and in parenchymal cells whose primary function is not mechanosensory.

Descriptor ID	D040542
MeSH Number(s)	G01.154.090.500 G02.111.820.580 G04.835.580
Concept/Terms	Mechanotransduction, Cellular Mechanotransduction, Cellular Signal Transduction, Mechanical Mechanical Signal Transduction Cellular Mechanotransduction Mechanosensory Transduction Transduction, Mechanosensory

Below are MeSH descriptors whose meaning is more general than "Mechanotransduction, Cellular".

Biological Sciences [G]
Physical Phenomena [G01]
Biophysical Phenomena [G01.154]
Biomechanical Phenomena [G01.154.090]
Mechanotransduction, Cellular [G01.154.090.500]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Signal Transduction [G02.111.820]
Mechanotransduction, Cellular [G02.111.820.580]
Cell Physiological Phenomena [G04]
Signal Transduction [G04.835]
Mechanotransduction, Cellular [G04.835.580]

Below are MeSH descriptors whose meaning is related to "Mechanotransduction, Cellular".

Below are MeSH descriptors whose meaning is more specific than "Mechanotransduction, Cellular".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Mechanotransduction, Cellular" by people in this website by year, and whether "Mechanotransduction, Cellular" was a major or minor topic of these publications.

Bar chart showing 24 publications over 14 distinct years, with a maximum of 4 publications in 2012 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	1	2
2009	2	0	2
2010	1	0	1
2011	1	0	1
2012	2	2	4
2013	0	1	1
2014	0	1	1
2017	1	0	1
2018	2	0	2
2019	3	1	4
2020	1	0	1
2021	2	0	2
2022	0	1	1
2024	0	1	1

Below are the most recent publications written about "Mechanotransduction, Cellular" by people in Profiles.

Vessella T, Xiang S, Xiao C, Stilwell M, Fok J, Shohet J, Rozen E, Zhou HS, Wen Q. DDR2 signaling and mechanosensing orchestrate neuroblastoma cell fate through different transcriptome mechanisms. FEBS Open Bio. 2024 May; 14(5):867-882.

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Gong J, Chen J, Gu P, Shang Y, Ruppell KT, Yang Y, Wang F, Wen Q, Xiang Y. Shear stress activates nociceptors to drive Drosophila mechanical nociception. Neuron. 2022 11 16; 110(22):3727-3742.e8.

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Kant S, Tran KV, Kvandova M, Caliz AD, Yoo HJ, Learnard H, Dolan AC, Craige SM, Hall JD, Jim?nez JM, St Hilaire C, Schulz E, Kr?ller-Sch?n S, Keaney JF. PGC1a Regulates the Endothelial Response to Fluid Shear Stress via Telomerase Reverse Transcriptase Control of Heme Oxygenase-1. Arterioscler Thromb Vasc Biol. 2022 01; 42(1):19-34.

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Holt JR, Tobin M, Elferich J, Gouaux E, Ballesteros A, Yan Z, Ahmed ZM, Nicolson T. Putting the Pieces Together: the Hair Cell Transduction Complex. J Assoc Res Otolaryngol. 2021 12; 22(6):601-608.

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Sato T, Verma S, Andrade CDC, Omeara M, Campbell N, Wang JS, Cetinbas M, Lang A, Ausk BJ, Brooks DJ, Sadreyev RI, Kronenberg HM, Lagares D, Uda Y, Pajevic PD, Bouxsein ML, Gross TS, Wein MN. A FAK/HDAC5 signaling axis controls osteocyte mechanotransduction. Nat Commun. 2020 07 01; 11(1):3282.

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Lele TP, Brock A, Peyton SR. Emerging Concepts and Tools in Cell Mechanomemory. Ann Biomed Eng. 2020 Jul; 48(7):2103-2112.

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Zhu L, Zhao W, Yan Y, Liao X, Bourtsalas A, Dan Y, Xiao H, Chen X. Interaction between mechanosensitive channels embedded in lipid membrane. J Mech Behav Biomed Mater. 2020 03; 103:103543.

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Dasgupta I, McCollum D. Control of cellular responses to mechanical cues through YAP/TAZ regulation. J Biol Chem. 2019 11 15; 294(46):17693-17706.

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Clark S, Elferich J, Gai J, Goehring A, Mitra J, Ha T, Gouaux E. Strategy for Compositional Analysis of the Hair Cell Mechanotransduction Complex Using TIRF Microscopy. Microsc Microanal. 2019 08; 25(Suppl 2):1266-1267.

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Zhu L, Cui Q, Xiao H, Liao X, Chen X. Gating and inactivation of mechanosensitive channels of small conductance: A continuum mechanics study. J Mech Behav Biomed Mater. 2019 02; 90:502-514.

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